Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

TSRI scientists find way to use new DNA-editing technology for DNA sequencing

Scientists at The Scripps Research Institute have found a way to apply a powerful new DNA-editing technology more broadly than ever before.

27 Aug 2013

Researchers uncover how SARS coronavirus uses host cell to reproduce itself

UC Irvine infectious disease researchers have uncovered components of the SARS coronavirus - which triggered a major outbreak of severe acute respiratory syndrome in 2002-03 - that allow it to take over host cells in order to replicate.

23 Aug 2013

Caris Life Sciences to facilitate patient access to tumour profiling service in Middle East and Africa

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of personalized medicine in oncology, has signed a distribution agreement with IPS Genomix to facilitate patient access to its tumour profiling service, Molecular Intelligence, in select Middle Eastern and African markets.

22 Aug 2013

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

A new publication in the top-ranked journal Neuron sheds new light onto the unknown processes on how the brain integrates the inputs from the different senses in the complex circuits formed by molecularly distinct types of nerve cells. The work was led by new Ume- University associate professor Paolo Medini.

21 Aug 2013

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Researchers at McGill University have found that sodium - the main chemical component in table salt - is a unique "on/off" switch for a major neurotransmitter receptor in the brain. This receptor, known as the kainate receptor, is fundamental for normal brain function and is implicated in numerous diseases, such as epilepsy and neuropathic pain.

21 Aug 2013

Pre-doctoral students receive International Student Research Fellowships from HHMI

The Howard Hughes Medical Institute has awarded two doctoral students from the Sackler School of Graduate Biomedical Sciences at Tufts University with 2013 International Student Research Fellowships. Seblewongel Asrat, from Ethiopia, studies the bacterium that causes Legionnaires' disease while Jennifer Nwankwo, from Nigeria, studies red blood cell dehydration in sickle cell disease.

17 Aug 2013

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms

The biological information that makes us unique is encoded in our DNA. DNA damage is a natural biological occurrence that happens every time cells divide and multiply. External factors such as overexposure to sunlight can also damage DNA.

17 Aug 2013

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Scientists at The Scripps Research Institute (TSRI) have discovered the molecular mechanism by which the deadly Ebola virus assembles, providing potential new drug targets.

16 Aug 2013

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Osteoarthritis is an extremely common condition affecting about 8 million people in the UK. The elderly are particularly susceptible, with up to 45% of people over 65 years, having the disease.

14 Aug 2013

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

CHD5 has previously been proposed as a tumour suppressor, acting as a brake that prevents healthy cells from developing into cancer cells. But the part played by the protein in healthy tissue, and whether this role is important for its ability to counter tumour growth, has remained largely uncharted.

14 Aug 2013

Discovery Transformation Program funds four projects for diabetes research

The Minnesota Partnership for Biotechnology and Medical Genomics announced four research projects selected for funding from the 2013 Discovery Transformation Grant Program.

13 Aug 2013

Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Vittorio Cristini, PhD, uses the example of an airplane to explain what he does in cancer research. "Before calculus," he says, "people couldn't really design a plane that would fly. You can do it by trial and error, but it would probably take centuries." Dr. Cristini has a faster way to try to understand cancer treatment. Like airplane designers today, he uses a mathematical model.

13 Aug 2013

Researchers create an efficient technique to target and repair defective genes

Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective genes.

13 Aug 2013

Specialized endocytocis play a crucial role in shaping cells themselves

The process cells use to 'swallow' up nutrients, hormones and other signals from their environment - called endocytosis - can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found.

12 Aug 2013

Study: Immune-regulating molecules can trigger lymphomas

A small group of immune-regulating molecules, when overproduced even moderately, can trigger the blood cancers known as lymphomas, according to a new study led by scientists from The Scripps Research Institute (TSRI).

9 Aug 2013

Children born by Caesarean section more vulnerable to allergies

Children who came into the world by Caesarean section are more often affected by allergies than those born in the natural way. The reason for this may be that they have a less diverse gut microbiota, according to a study by universities in Sweden and Scotland.

9 Aug 2013

Penn State researchers find that protein changes can control gene functions

A Penn State-led research team has found that changes to proteins called histones, which are associated with DNA, can control whether or not a gene is allowed to function. The changes may be important in maintaining the genes' "expression potential" so that future cells behave as their parent cells did.

8 Aug 2013

UCLA researchers invent research maps to help neuroscientists choose what to study next

Before the digital age, neuroscientists got their information in the library like the rest of us. But the field's explosion has created nearly 2 million papers -- more data than any researcher can read and absorb in a lifetime.

8 Aug 2013

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Researchers have discovered a novel mechanism responsible for the loss of a critical tumor-suppressor gene in rhabdomyosarcoma and other soft-tissue sarcomas, rare cancers that strike mainly children and often respond poorly to treatment. Their cause is largely unknown.

8 Aug 2013

Findings may allow lower doses of chemotherapy, limit toxic side effects

In research recently published in Nature Structural & Molecular Biology, Alessandro Vindigni, Ph.D., associate professor of biochemistry and molecular biology at Saint Louis University, discovered how cancer cells respond to the damage caused by an important class of anti-cancer drugs, topoisomerase I inhibitors.

7 Aug 2013

Molecular Biology News and Research

Further Reading

TSRI scientists find way to use new DNA-editing technology for DNA sequencing

Researchers uncover how SARS coronavirus uses host cell to reproduce itself

Caris Life Sciences to facilitate patient access to tumour profiling service in Middle East and Africa

Study shows how brain integrates inputs from different senses in complex circuits of nerve cells

Sodium act as "on/off" switch for major neurotransmitter receptor in brain

Pre-doctoral students receive International Student Research Fellowships from HHMI

Michigan researchers use TACC supercomputers to understand DNA bending, repair mechanisms

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Osteoarthritis research: an interview with Dr Deborah Mason, Cardiff University

Trinity researchers reveal CHD5 protein acts as tumor suppressor in nervous system development

Discovery Transformation Program funds four projects for diabetes research

Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Researchers create an efficient technique to target and repair defective genes

Specialized endocytocis play a crucial role in shaping cells themselves

Study: Immune-regulating molecules can trigger lymphomas

Children born by Caesarean section more vulnerable to allergies

Penn State researchers find that protein changes can control gene functions

UCLA researchers invent research maps to help neuroscientists choose what to study next

Researchers identify mechanism responsible for loss of tumor-suppressor gene in soft-tissue sarcomas

Findings may allow lower doses of chemotherapy, limit toxic side effects

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