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Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

An off-the-shelf dietary supplement available for pennies per dose demonstrated the ability to reverse cellular damage linked to specific genetic mutations in transgenic fruit flies, an experimental model of genetic mutation-induced renal cell injury that features striking similarities to humans, a Children's National Health System research team reports April 20 in Journal of the American Society of Nephrology.

21 Apr 2017

Latest advances in antibody delivery mediated by rAAV for treatment of chronic and infectious diseases

Monoclonal antibody-based therapies have revolutionized treatments of cancer and autoimmune diseases because of their specificity and limited toxicity.

21 Apr 2017

Strawberry extract can inhibit spread of breast cancer cells, mice study shows

A study by European and Latin American researchers has shown that strawberry extract can inhibit the spread of laboratory-grown breast cancer cells, even when they are inoculated in female mice to induce tumours.

19 Apr 2017

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new treatments, according to a study led by Georgia State University.

18 Apr 2017

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.

18 Apr 2017

Discovery of additional viral reservoir reveals new target for HIV cure research

HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system.

17 Apr 2017

Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients

Parkinson disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

12 Apr 2017

New nanowire technology may serve as platform to screen drugs for neurological diseases

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail.

11 Apr 2017

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Marc Symons, PhD, professor in The Feinstein Institute for Medical Research's Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers.

11 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

Researchers in Germany have developed a transgenic mouse that could help scientists identify new influenza virus strains with the potential to cause a global pandemic.

10 Apr 2017

New research sheds light on movement of white blood cells to sites of infection

One of the mysteries of the living body is the movement of cells - not just in the blood, but through cellular and other barriers.

10 Apr 2017

Using nanodiamonds to see smaller

Many of the most fundamental, life governing biological processes take place at size and time scales that remain invisible with current imaging technologies. Understanding how the molecules that underlie these processes move, interact and change could pave the way for new treatments, cures and the development of novel drug therapies.

7 Apr 2017

MSU and Venn Therapeutics develop promising therapy to delay B16 melanoma tumor growth

Michigan State University researchers presented promising cancer therapy results at the American Association for Cancer Research International Meeting in Washington, DC.

5 Apr 2017

Researchers develop stable brain implant based on anti-inflammatory coating

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull's interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over time.

5 Apr 2017

Scientists find new drug target to improve cardiac output in heart failure patients

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients.

4 Apr 2017

Could light from LED screens cause irreversible eye damage?

The study carried out by the Complutense University of Madrid (Spain) –UCM – is the first to evaluate retinal damage using tablets with LED screens available in the market with living animals.

30 Mar 2017

Researchers show how dopamine falls and fluctuates during migraine headache

Using PET scans of the brain, University of Michigan researchers showed that dopamine falls and fluctuates at different times during a migraine headache.

29 Mar 2017

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

All causes of the most common form of liver cancer, hepatocellular carcinoma, are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.

29 Mar 2017

Phase-contrast X-ray imaging could identify tumors earlier

Phase-contrast X-ray imaging differs from conventional X-rays because it uses a different physical principle.

29 Mar 2017

in vivo News and Research

Transgenic fruit flies can shed light on genetic mutations that underlie kidney disease in humans

Latest advances in antibody delivery mediated by rAAV for treatment of chronic and infectious diseases

Strawberry extract can inhibit spread of breast cancer cells, mice study shows

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

Researchers find new way to prevent graft-versus-host disease after stem cell transplants

Discovery of additional viral reservoir reveals new target for HIV cure research

Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients

New nanowire technology may serve as platform to screen drugs for neurological diseases

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Researchers design first light-activated drug for treatment of pain

New transgenic mouse could help monitor potential dangers of emerging influenza viruses

New research sheds light on movement of white blood cells to sites of infection

Using nanodiamonds to see smaller

MSU and Venn Therapeutics develop promising therapy to delay B16 melanoma tumor growth

Researchers develop stable brain implant based on anti-inflammatory coating

Scientists find new drug target to improve cardiac output in heart failure patients

Could light from LED screens cause irreversible eye damage?

Researchers show how dopamine falls and fluctuates during migraine headache

Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer

Phase-contrast X-ray imaging could identify tumors earlier

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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