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Researchers make progress towards a new diagnostic test for schistosomiasis

Researchers have made important progress towards a new diagnostic test for schistosomiasis, which could help the World Health Organization achieve its goal of interrupting transmission of the disease, and eventually eliminating it.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

Monitoring cellular metabolism for NAFLD/NASH liver disease research

In this interview, Jolanta Vidugiriene, a Senior Research Scientist at Promega Corporation, talks to News-Medical about tools for studying metabolism in NAFLD/NASH research.

From Promega Corporation 22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

In this interview, News-Medical speaks to Professor Weibke Arlt about her recent research into how the contraceptive pill affects type 2 diabetes in women with PCOS.

22 Nov 2021

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

A new study published in the journal mBio investigates different antibodies from convalescent donors that bind three separate domains of the SARS-CoV-2 spike. The results of this study suggest that the individuals exposed to the SARS-CoV-2 from the first wave have neutralizing antibodies against current variants.

21 Nov 2021

UC researchers engineer new probiotic to target and break down cancer cell defenses

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways.

21 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Researchers identified a subset of species in which the threat of spillback infection appears the most significant due to location and increased contact with humans in areas with a high prevalence of SARS-CoV-2.

19 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

Study reveals complex interplay between diet, gut microbiota, and immune function

The cliché "you are what you eat" has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome.

17 Nov 2021

SARS-CoV-2 reinfection associated with housing instability

Researchers examine the impact of demographic factors and antibody responses following SARS-CoV-2 reinfection.

17 Nov 2021

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

A recent study sed PBPK modeling to demonstrate the use of DEX PKs for the treatment of COVID-19 in patients with liver impairment.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

Ensemble cryo-electron microscopy uncovers conformational states of the nsp13 helicase of SARS-CoV-2

With this background, the goal of a new study published on the bioRxiv* preprint server was to use cryo-electron microscopy to investigate the nsp13 helicase conformational states in order to gain insights of how nsp13 functions during viral transcription/replication.

16 Nov 2021

Enzyme News and Research

Researchers make progress towards a new diagnostic test for schistosomiasis

Paper-based innovations for COVID-19 diagnosis

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Monitoring cellular metabolism for NAFLD/NASH liver disease research

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

Importance of cross-neutralizing antibodies against SARS-CoV-2 variants

UC researchers engineer new probiotic to target and break down cancer cell defenses

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

The antiviral function of BET protein against SARS-CoV-2 infection

Scientists use advanced microscopes to delve deeper into protein degradation process

Study reveals complex interplay between diet, gut microbiota, and immune function

SARS-CoV-2 reinfection associated with housing instability

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Ensemble cryo-electron microscopy uncovers conformational states of the nsp13 helicase of SARS-CoV-2

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo