immunity News and Research

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Hybrid immunity and booster vaccination provides best protection against SARS-CoV-2 BA.1 and BA.2

Researchers analyze the effect of prior infection, vaccination, and hybrid immunity against SARS-CoV-2 BA.1 and BA.2 Omicron subvariant infections.

28 Mar 2022

Evaluating severity of influenza infection in ferrets with COVID-19 history

In a new study, researchers investigated the effect of SARS-CoV-2 exposure on the severity of influenza in ferrets.

28 Mar 2022

Dynamics of SARS-CoV-2 viral load in vaccinated and recovered individuals

A new study assessed the dynamics of viral load of SARS-CoV-2 Omicron and Delta variants of concern post-vaccination and previous infection.

28 Mar 2022

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Researchers applied a previously developed thermostable self-amplifying ribonucleic acid vaccine to COVID-19.

28 Mar 2022

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

A recent study investigated the potency and functionality of T-cell and humoral responses against the SARS-CoV-2 wild-type strain and its variants.

28 Mar 2022

Study estimates protection against reinfection following primary SARS-CoV-2 infection

A recent study investigated the protection provided by the primary SARS-CoV-2 infection against reinfection.

28 Mar 2022

Climate change may push the US toward the ‘goldilocks zone’ for West Nile virus

Michael Keasling of Lakewood, Colorado, was an electrician who loved big trucks, fast cars, and Harley-Davidsons. He'd struggled with diabetes since he was a teenager, needing a kidney transplant from his sister to stay alive.

28 Mar 2022

Benefits of heterotypic vaccination against variants of SARS-CoV-2

A new study evaluated the antibody responses against the newly emerged SARS-CoV-2 Omicron variant upon heterotypic vaccination in animal models.

28 Mar 2022

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Researchers designed a dynamic mathematical model to simulate the transmission of the SARS-CoV-2 Omicron variant in China and project its associated burden on healthcare facilities, should the zero-COVID-19 policy be lifted.

28 Mar 2022

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

A recent study investigated the disease severity of SARS-CoV-2 Omicron BA.2 infection among Hong Kong children.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

Tuberculosis infection protects mice against COVID-19

To study if prior Mtb infection affects the response to CoV2 infection, K18-hACE2 (ACE2) and C57BL/6 (B6) mice were infected with Mtb, and post thirty days, were exposed to CoV2.

27 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

Novel SARS-CoV-2 strains found to have low impact on CD8 T lymphocytes

Researchers investigated the impact of mutations in the SARS-CoV-2 variants of interest and variants of concern on the properties of the cluster of differentiation 8 T lymphocytes.

25 Mar 2022

New insights into SARS-CoV-2 immunity gained from natural infection

Antibody-secreting cells (ASCs) peaked at 3-4 weeks and were still being produced at 3-4 months in patients hospitalized with COVID-19, according to a study published in the peer-reviewed journal Viral Immunology.

25 Mar 2022

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Researchers determined the impact of vitamin D status in preventing all-cause acute respiratory infection and SARS-CoV-2 infection.

25 Mar 2022

Effectiveness of social distancing on COVID-19 infections and fatalities

Researchers evaluated the effectiveness of social distancing measures adopted to curb the spread of COVID-19.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

A new study identified unique truncated open reading frame 8 proteins among SARS-CoV-2 sequences.

25 Mar 2022

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection incites adaptive cellular immune responses. In many SARS-CoV-2 studies, peripheral blood is analyzed to study the immune responses. Now, a new study under consideration at the Nature Portfolio Journal analyzes the peripheral blood, tonsils, and adenoids of children to understand local and systemic immune responses to SARS-CoV-2.

25 Mar 2022

immunity News and Research

Hybrid immunity and booster vaccination provides best protection against SARS-CoV-2 BA.1 and BA.2

Evaluating severity of influenza infection in ferrets with COVID-19 history

Dynamics of SARS-CoV-2 viral load in vaccinated and recovered individuals

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Study estimates protection against reinfection following primary SARS-CoV-2 infection

Climate change may push the US toward the ‘goldilocks zone’ for West Nile virus

Benefits of heterotypic vaccination against variants of SARS-CoV-2

Mathematical model of SARS-CoV-2 transmission tailored to the unique situation of China

Severe outcomes in hospitalized children during the Omicron BA.2-dominated fifth wave in Hong Kong

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

Tuberculosis infection protects mice against COVID-19

CDK6: a potential drug target for severe COVID-19

Novel SARS-CoV-2 strains found to have low impact on CD8 T lymphocytes

New insights into SARS-CoV-2 immunity gained from natural infection

Effectiveness of a 'test-and-treat' approach for identification and treatment of vitamin D insufficiency for prevention of COVID-19

Effectiveness of social distancing on COVID-19 infections and fatalities

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

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