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Computers used to create predictive models of human disease

Increased use of computers to create predictive models of human disease is likely following a workshop organised by the European Science Foundation (ESF), which urged for a collaborative effort between specialists in the field.

12 Nov 2008

A large waistline doubles your risk of premature death

Having a large waistline can almost double your risk of dying prematurely even if your body mass index is within the 'normal' range, according to a new study of over 350,000 people across Europe, published in the New England Journal of Medicine.

12 Nov 2008

Breakthrough in rheumatoid arthritis research

Rheumatoid arthritis is a painful, inflammatory type of arthritis that occurs when the body's immune system attacks itself.

12 Nov 2008

Researchers uncover beneficial mechanism of the helpful "Dr. Jekyll" side of the Cdk5 protein

Researchers at UT Southwestern Medical Center have uncovered new insights into the "Dr. Jekyll and Mr. Hyde" nature of a protein that stimulates stem-cell maturation in the brain but, paradoxically, can also lead to nerve-cell damage.

12 Nov 2008

New study focuses on adolescents and young adults at risk for psychosis

Emory University in Atlanta is playing a key role in the largest, most comprehensive study ever funded by the National Institute of Mental Health (NIMH) of adolescents and young adults at risk for developing a psychotic disorder.

12 Nov 2008

Newborn neurons in the adult brain can settle in the wrong neighborhood

A new study published in this week's PLoS Biology could have significant consequences for neural tissue transplantation to treat brain injuries or neural degeneration.

11 Nov 2008

Genetics for personalized coronary heart disease treatment

Identifying a single, common variation in a person's genetic information improves prediction of his or her risk of a heart attack or other heart disease events and thus, choice of the best treatment accordingly, said researchers at Baylor College of Medicine in Houston.

11 Nov 2008

Does HBV infection induce acute cellular DNA damage?

Eukaryotic cells employ multiple strategies of checkpoint signaling and DNA repair mechanisms to monitor and repair damaged DNA.

11 Nov 2008

Taking calcium and vitamin D supplements does not reduce breast cancer risk

Taking calcium and vitamin D supplements does not reduce breast cancer incidence in postmenopausal women, according to data from a randomized, doubled-blind, placebo-controlled trial published online November 11 in the Journal of the National Cancer Institute.

11 Nov 2008

All stem cells are not created equal, explains expert

During the course of the Presidential campaign, Obama signaled his intention to reverse Bush's controversial limit on federal funding of embryonic stem cell research.

11 Nov 2008

New technique to study the genetics of breast cancer

A new technique to study genetic changes that can lead to breast cancer could be one step closer.

11 Nov 2008

Raptor Pharmaceuticals announces positive results for Convivia program

Raptor Pharmaceuticals Corp. has announced positive results in its Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

11 Nov 2008

Folic acid does not offer any cardiovascular benefits

Folic acid is safe - but it lacks any cardiovascular benefits - according to researchers presenting at the American Heart Association's Scientific Sessions 2008. The results from the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH), a 12,064-person, randomized study, were presented as a late-breaking clinical trial.

11 Nov 2008

New genetic kidney atlas will explain kidney disease

An international team of researchers, which included scientists from the University of Queensland, have generated an atlas of genes involved in kidney formation.

11 Nov 2008

Protein can nurture or devastate brain cells, depending on its 'friends,' UT Southwestern researchers find

11 Nov 2008

Signaling between protein, growth factor is critical for coordinated cell migration

The mysterious process that orchestrates cells to move in unison to form human and animal embryos, heal wounds, and even spread cancer depends on interaction between two well-known genetic signaling pathways, two University of Utah medical school researchers have discovered.

11 Nov 2008

Astragalus root plant chemical used to fight HIV

Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division.

11 Nov 2008

Newborn neurons in the adult brain can settle in the wrong neighborhood

In a study that could have significant consequences for neural tissue transplantation strategies, researchers at the Salk Institute for Biological Studies report that inactivating a specific gene in adult neural stem cells makes nerve cells emerging from those precursors form connections in the wrong part of the adult brain.

11 Nov 2008

First comprehensive genetic blueprint of a forming mammalian organ

Part of an international consortium sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a research team led by Cincinnati Children's Hospital Medical Center reports the creation of a detailed genome-based atlas for understanding healthy and abnormal kidney development and disease.

11 Nov 2008

New analysis of the mechanisms that drive evolution in viruses and bacteria

It sounds like a science fiction movie: A killer contagion threatens the Earth, but scientists save the day with a designer drug that forces the virus to mutate itself out of existence.

11 Nov 2008