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Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

Cells use their molecular architecture to regulate their metabolic functions, and repairing diseased cells' architecture to a healthier state can also repair metabolism, according to a study led by Harvard T.H. Chan School of Public Health researchers.

10 Mar 2022

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

Researchers at UNIGE show that the experience of impending cell death within a primary tumor can lead to the development of pro-metastatic cells.

10 Mar 2022

Active compound in Chinese herbs prevents colon cancer in mice

The active compound in Chinese herbs called emodin can prevent colon cancer in mice, according to researchers at the University of South Carolina School of Medicine.

9 Mar 2022

Researchers secure $12 million grant to develop improved therapies for hemophilia

An Indiana University School of Medicine researcher will lead a multi-institute effort toward improved therapies for hemophilia with help from a $12 million grant from the National Heart Lung and Blood Institute.

8 Mar 2022

Rising global temperatures likely to increase the health burden from hyponatremia

Global warming is likely to increase the number of people requiring hospitalization due to critically low sodium levels in the blood, a condition known as hyponatremia.

8 Mar 2022

How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

Some blood cells remain in tissues for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

7 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

New, highly promising strategy to overcome a key cause of cancer deaths

A research team led by scientists at Albert Einstein College of Medicine has devised a novel and highly promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them.

7 Mar 2022

Aldosterone levels undetectably low in hospitalized COVID-19 patients

A new study reports finds very low aldosterone levels in a subset of COVID-19 patients.

6 Mar 2022

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

A high-fat diet is not enough to cause short-term fatty liver disease. However, if this diet is combined with the intake of beverages sweetened with liquid fructose, the accumulation of fats in the liver accelerates and hypertriglyceridemia —a cardiovascular risk factor— can appear.

4 Mar 2022

When teens blow off parents’ pleas to get vaccinated, the consequences can be deadly

Kennedy Stonum, a high school junior, deflected repeated entreaties from her father to please just get vaccinated against covid-19.

4 Mar 2022

Discovery could open new doors in the field of blood pressure research

The research group of internal medicine at the University of Oulu, Finland, has discovered a previously unknown blood pressure-regulating circuit.

4 Mar 2022

Consuming wine with meals linked to lower risk of developing type 2 diabetes

An analysis of health data for nearly 312,400 current drinkers suggests consuming alcohol, most notably wine, with meals is associated with a lower risk of developing type 2 diabetes, according to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022.

4 Mar 2022

Women's diet may play a role in the development of hypertensive disorder of pregnancy

Diet may play a role in the development of dangerous high blood pressure in late pregnancy among some Hispanic/Latina women, according to preliminary research to be presented at the American Heart Association's Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022.

3 Mar 2022

Long or irregular menstrual cycles may be linked with increased risk of NAFLD

Women with long or irregular periods are known to have a higher risk of type 2 diabetes and heart disease, but researchers found these women may also be at risk for nonalcoholic fatty liver disease (NAFLD), according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

3 Mar 2022

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

A new study assesses breakthrough SARS-CoV-2 infections in vaccinated CLD patients with cirrhosis as compared to CLD patients without cirrhosis.

3 Mar 2022

Equine hepatitis viruses help gain new insights into the behavior of hepatitis C virus in humans

Research comparing viruses found in humans and horses provides insights that may aid vaccine development.

2 Mar 2022

Liver News and Research

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Targeting regulation of subcellular architecture may hold opportunities to treat metabolic diseases

'Post-apoptotic pro-metastatic cells' appear to be potential metastasis prevention targets

Active compound in Chinese herbs prevents colon cancer in mice

Researchers secure $12 million grant to develop improved therapies for hemophilia

Rising global temperatures likely to increase the health burden from hyponatremia

How have human organoids been used in research to study SARS-CoV-2?

Some blood cells remain in tissues for years, research finds

NETosis in COVID-19 and MIS-C

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

New, highly promising strategy to overcome a key cause of cancer deaths

Aldosterone levels undetectably low in hospitalized COVID-19 patients

High-fat diet combined with liquid fructose intake accelerates fat accumulation in the liver

When teens blow off parents’ pleas to get vaccinated, the consequences can be deadly

Discovery could open new doors in the field of blood pressure research

Consuming wine with meals linked to lower risk of developing type 2 diabetes

Women's diet may play a role in the development of hypertensive disorder of pregnancy

Long or irregular menstrual cycles may be linked with increased risk of NAFLD

Incidence and outcomes of breakthrough SARS-CoV-2 infections in vaccinated chronic liver disease patients

Equine hepatitis viruses help gain new insights into the behavior of hepatitis C virus in humans

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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