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Scientists discover how Streptococcus pyogenes can obtain nutrition from the skin surface

Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses, such as sepsis and toxic shock.

31 Mar 2021

Early treatment with anti-VEGF injections slows diabetic retinopathy

Early treatment with anti-VEGF injections slowed diabetic retinopathy in a clinical study from the DRCR Retina Network (DRCR.net). However, two years into the four-year study its effect on vision was similar to standard treatment, which usually begins at the onset of late disease.

31 Mar 2021

Widely available drug reduces morbidity, mortality in COVID-19-infected mice

Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.

31 Mar 2021

COVID-19 patients with dementia have higher risk for complications, mortality

Early in the pandemic, neurologists expressed concern that COVID-19 patients with dementia may be at higher risk for complications and mortality.

31 Mar 2021

COVID-19 associated seizures may increase death risk in patients

COVID-19 can have damaging effects on multiple organs in the body, including the brain. A new study led by investigators at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) indicates that some hospitalized patients with COVID-19 experience non-convulsive seizures, which may put them at a higher risk of dying. The findings are published in the Annals of Neurology.

31 Mar 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

NIAID researchers identify key player in the immune response to SARS-CoV-2

When variants of SARS-CoV-2 (the virus that causes COVID-19) emerged in late 2020, concern arose that they might elude protective immune responses generated by prior infection or vaccination, potentially making re-infection more likely or vaccination less effective.

31 Mar 2021

Study finds remarkable differences in the way individuals respond to malaria

Scientists have discovered that tracking malaria as it develops in humans is a powerful way to detect how the malaria parasite causes a range of infection outcomes in its host.

31 Mar 2021

New Columbia University center provides specialized care for Lyme and tick-borne diseases

A new center that will provide specialized care for patients with Lyme disease and other tick-borne diseases will begin seeing patients this summer at Columbia University's Vagelos College of Physicians and Surgeons.

31 Mar 2021

Comparing the transmission routes of two SARS-CoV-2 variants of concern

The research team had previously identified the UK variant as having higher viral RNA shedding than the D614G variant. However here, they wanted to compare the transmission of such variants through different routes of potential infection: direct contact, aerosol (airborne droplets), and fomite (objects which may be contaminated and therefore spread infectious agents).

30 Mar 2021

Study shows how innate valence is encoded

Since the beginning of the pandemic, a loss of smell has emerged as one of the telltale signs of COVID-19. Though most people regain their sense of smell within a matter of weeks, others can find that familiar odors become distorted.

30 Mar 2021

FDA-approved cancer drug blunts SARS-CoV-2 protein's detrimental effects

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2 - the virus that causes COVID-19 – and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects. In their experiments in fruit flies and human cell lines, the team discovered the cell process that the virus hijacks, illuminating new potential candidate drugs that could be tested for treating severe COVID-19 disease patients.

29 Mar 2021

Study: Common medications are often derived from animal byproducts

More physicians and pharmacists are advocating for patients to be made aware of animal byproducts contained in common medications, according to new research in the Journal of Osteopathic Medicine.

29 Mar 2021

UVA-led researchers urge rapid action to better prepare for the next pandemic

An international team of researchers led by a University of Virginia School of Medicine professor is warning that scientists must better prepare for the next pandemic - and has developed a plan to do just that.

29 Mar 2021

UVA scientists identify a potential way to prevent heart attacks and strokes

Scientists at the University of Virginia School of Medicine have identified a potential way to head off heart attacks and strokes by strengthening the fibrous caps overlying atherosclerotic plaques that naturally accumulate inside our arteries.

27 Mar 2021

Researchers identify new drug candidates for treating patients with severe COVID-19

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2--the virus that causes COVID-19 - and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects.

27 Mar 2021

Heidelberg researchers introduce a reproducible division mechanism for synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism for synthetic vesicles.

27 Mar 2021

New study uncovers potential therapeutic target for lupus

A recent study published in JCI found that a neutrophil's endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus.

26 Mar 2021

U-M Depression Center to be renamed in recognition of Eisenbergs' philanthropy toward the center

The University of Michigan Board of Regents today approved the renaming of the U-M Depression Center for Frances and Kenneth Eisenberg and their family, in recognition of their transformational $30 million total giving to depression research and scholarship.

26 Mar 2021

Salk joins a long list of recipients included in The Conrad Prebys Foundation’s inaugural grant cycle

Salk Professor Thomas Albright has been awarded $1 million and Assistant Professor Edward Stites awarded $500,000 by The Conrad Prebys Foundation as part of its inaugural round of grants.

26 Mar 2021