Pharmaceuticals News and Research

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Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

Methane is the world's most abundant hydrocarbon. It's the major component of natural gas and shale gas and, when burned, is an effective fuel. But it's also a major contributor to climate change, with 24 times greater potency as a greenhouse gas than carbon dioxide.

25 Mar 2016

CRPS rank higher on pain scales than childbirth, cancer, amputation

Imagine pain in an arm or leg so intense that the sufferer would rather undergo an amputation than put up with it any longer. For those with complex regional pain syndrome (CRPS), this is not just a hypothetical nightmare—it is reality.

25 Mar 2016

TSRI scientists develop new process to synthesize naturally occurring compound phorbol

In a landmark feat of chemical synthesis, scientists at The Scripps Research Institute have developed a 19-step process for making the naturally occurring compound phorbol in the laboratory, in quantities that are useful for pharmaceutical research.

24 Mar 2016

Researchers develop versatile building blocks that could be useful in pharmaceutical research

Researchers in the Doyle lab at Princeton have developed a direct cross-coupling reaction to produce nitrogen-containing compounds called 1,2-dihydropyridines, versatile building blocks that are highly useful in pharmaceutical research.

24 Mar 2016

Chinese medicines may contain hazardous chemicals

Chinese medicines are manufactured and distributed all over the world. Many people perceive them as natural, even benign and with few side effects, but regulation of human medicines fluctuates widely in different countries.

24 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

FEI, NovAliX to jointly provide cryo-EM-based structural analysis services for pharmaceutical and biotech industry

FEI and NovAliX, a contract research organization (CRO), announced today a strategic partnership to enable NovAliX to provide commercial cryo-electron microscopy (EM)-based structural analysis services to its customers in the pharmaceutical and biotech industry.

From Thermo Fisher Scientific – Electron Microscopy Solutions 23 Mar 2016

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Takeda Pharmaceutical Company Limited, (“Takeda”) today announced that the interim findings from the GEMINI Long-Term Safety (LTS) study were presented during the 2016 European Crohn's and Colitis Organisation (ECCO) Annual Scientific Meeting in Amsterdam, The Netherlands.

22 Mar 2016

Advanced genomic sequencing tracks deadly blood infection in cancer patients

The Translational Genomics Research Institute, working with international investigators, have discovered the source of a potential deadly blood infection in more than 50 South American cancer patients.

21 Mar 2016

KORs could be potential drug target for treatment of addiction, anxiety disorders

University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that regulates emotion.

21 Mar 2016

Trimeprazine improves β cell function, slows progression of diabetes

β cells in pancreatic islets are responsible for producing insulin, which is essential to regulate blood glucose homeostasis. In type 1 diabetes, pancreatic β cells are destroyed due to an autoimmune attack, whereas in type 2 diabetes, pancreatic β cells may have deficiencies in secreting insulin or insulin-responding tissues can become insulin resistant.

21 Mar 2016

Innovative treatment may help prevent brain swelling, death in stroke patients

New research has provided more evidence that an innovative treatment strategy may help prevent brain swelling and death in stroke patients. J. Marc Simard, professor of neurosurgery at the University of Maryland School of Medicine, along with colleagues at Yale University and Massachusetts General Hospital, found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who had suffered a type of large stroke called malignant infarction, which normally carries a high mortality rate.

19 Mar 2016

Breckenridge Pharmaceutical announces final FDA approval for Gabapentin Oral Solution

Breckenridge Pharmaceutical, Inc. announces the final approval by the U.S. Food and Drug Administration of the Abbreviated New Drug Application for Gabapentin Oral Solution 250 mg per 5 mL, which is AA rated to Neurontin, a drug marketed by Pfizer.

18 Mar 2016

Automated techniques could dramatically accelerate antimicrobial discovery

The antimicrobial arsenal that we count on to save millions of lives each year is alarmingly thin--and these microbes are rapidly evolving resistance to our weapons. But help may be on the way: In a study posted in the AMB Express, researchers from the National Institute of Standards and Technology show that automated techniques commonly used to screen new drugs for mammalian cell toxicity could also dramatically speed up the challenging task of antimicrobial discovery.

17 Mar 2016

Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

Panasonic’s new MCO-170M multi gas incubators provide outstanding quality and performance alongside advanced O2 and CO2 control to maximise cell culture efficiency and optimise results and reproducibility.

From PHC Europe B.V. 17 Mar 2016

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Seldom can one say $3.8 million is just the tip of the iceberg, but a newly awarded grant from Gilead Sciences, Inc. is just that. MUSC transplant surgeon Kenneth Chavin, M.D., Ph.D., says the true value of the multi-center drug trial is closer to $26 million, including $22 million in free drugs provided by the pharmaceutical company.

17 Mar 2016

Scientists outline strategies that could help curb global water scarcity

Millions of people around the world lack access to clean drinking water, and experts predict the situation could get worse unless new solutions are implemented. A panel of scientists addressing the issue outlines strategies that could help curb this humanitarian crisis in a new white paper, "Chemistry and Water: Challenges and Solutions in a Changing World."

16 Mar 2016

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

In global clinical trials, patients with advanced metastatic lung cancer who were treated with a targeted immunotherapy drug lived significantly longer and with fewer side effects than those who received standard second-line chemotherapy, according to a new Kaiser Permanente study published today in the journal The Lancet.

15 Mar 2016

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

DelMar Pharmaceuticals, Inc., announced today that the FDA Office of Orphan Products Development (OOPD) has granted orphan drug designation for its lead product candidate, VAL-083, in the treatment of medulloblastoma.

15 Mar 2016

Bruker expands capabilities of NMR-based Assure-RMS solution with launch of Chemometrics Module

Bruker Corporation introduces the Chemometrics Module, further expanding the capabilities of its proven Assure-RMS solution. Fully automated, quantitative and qualitative Nuclear Magnetic Resonance (NMR) analysis enables material screening in the polymer, pharmaceutical and dietary supplement industries.

From Bruker BioSpin Division 15 Mar 2016

Pharmaceuticals News and Research

Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

CRPS rank higher on pain scales than childbirth, cancer, amputation

TSRI scientists develop new process to synthesize naturally occurring compound phorbol

Researchers develop versatile building blocks that could be useful in pharmaceutical research

Chinese medicines may contain hazardous chemicals

Cinqair (reslizumab) approved for treatment of severe asthma

FEI, NovAliX to jointly provide cryo-EM-based structural analysis services for pharmaceutical and biotech industry

GEMINI LTS study: Patients with active ulcerative colitis report clinical improvements with vedolizumab treatment

Advanced genomic sequencing tracks deadly blood infection in cancer patients

KORs could be potential drug target for treatment of addiction, anxiety disorders

Trimeprazine improves β cell function, slows progression of diabetes

Innovative treatment may help prevent brain swelling, death in stroke patients

Breckenridge Pharmaceutical announces final FDA approval for Gabapentin Oral Solution

Automated techniques could dramatically accelerate antimicrobial discovery

Panasonic introduces new MCO-170M multi gas incubators to optimise cell culture efficiency and productivity

MUSC surgeon awarded $3.8 million grant to evaluate transplant drug

Scientists outline strategies that could help curb global water scarcity

Experimental drug improves survival rate of majority of lung cancer patients compared to standard chemotherapy

DelMar's VAL-083 receives FDA orphan drug designation for treatment of medulloblastoma

Bruker expands capabilities of NMR-based Assure-RMS solution with launch of Chemometrics Module

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