Efficacy News and Research

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What are the efficacy and safety of psilocybin in patients with major depressive disorder?

The safety, timing, magnitude, and durability of the antidepressant psilocybin on patients with major depressive disorders.

4 Sep 2023

Study highlights risks of high-dose naloxone in opioid overdose response

Whether regular distribution of two intranasal or intramuscular administrations of low-dose naloxone was effective and adequate in reversing opioid overdoses.

4 Sep 2023

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.

4 Sep 2023

Big Tuna and automated buffer exchange: An interview with Unchained Labs

In this interview, AZoNetwork speaks with Joe Barco, the Senior Director of Workflow Marketing at Unchained Labs, about the benefits of automated buffer exchange with Big Tuna.

From Unchained Labs 4 Sep 2023

Scientists reclassify 200 rare immune system disorders using network-based approach

Scientists at CeMM, Max Perutz Labs, and St. Anna Children's Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders.

1 Sep 2023

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) cediranib did not make a difference in outcomes for treating patients with an advanced form of thyroid cancer that develops from thyroid follicular cells called differentiated thyroid cancer (DTC).

1 Sep 2023

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

Amgen today announced the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell lung cancer (NSCLC) at a meeting on Oct. 5, 2023.

From AMGEN 1 Sep 2023

The efficacy and safety of anti-androgens in the management of hormonal and clinical features of PCOS

The safety and efficacy of anti-androgens in managing polycystic ovary syndrome (PCOS).

1 Sep 2023

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

A new paper explores the dietary effects of consuming colorful fruits and vegetables (CFV).

1 Sep 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study from Karolinska Institutet published in The Journal of Clinical Investigation shows.

31 Aug 2023

Study finds semaglutide provides benefits for patients with obesity phenotype of heart failure and HFpEF

Researchers evaluated the efficacy of semaglutide in patients with the obesity phenotype of heart failure and preserved ejection fraction.

31 Aug 2023

Study explores the potential of robotic-assisted TMS for depression

In a recent study published in the Scientific Reports, a group of researchers evaluated the efficiency, therapeutic efficacy, and patient perceptions of a custom robotic system for transcranial magnetic stimulation (TMS) coil placement in treating depression compared to traditional manual methods.

31 Aug 2023

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

The study finds that the fourth dose of the COVID-19 mRNA vaccine significantly boosts neutralizing antibody levels in the elderly, providing enhanced protection against new SARS-CoV-2 variants like Omicron. This supports the efficacy of booster shots for older populations in combating COVID-19.

31 Aug 2023

ADHD drug could serve as a cocaine-replacement therapy

Cocaine use continues to be a public health problem, yet despite concerted efforts, no drugs have been approved to resolve cocaine addiction. Research suggests that the attention-deficit/hyperactivity disorder drug methylphenidate (MPH; Ritalin) could serve as a cocaine-replacement therapy, but clinical results have been mixed.

30 Aug 2023

Engineered ACE2 decoy shows promise as COVID-19 treatment

Researchers from Japan demonstrated that an engineered angiotensin-converting enzyme 2 (ACE2) receptor, which showed the potential to remarkably reduce the emergence of resistant virus strains, could successfully exert its therapeutic effect in primates, which may open avenues for the application of the technology for the treatment of humans.

30 Aug 2023

Efficacy News and Research

What are the efficacy and safety of psilocybin in patients with major depressive disorder?

Study highlights risks of high-dose naloxone in opioid overdose response

New cancer therapy shows promise in mouse models, slows or reverses tumor growth

Big Tuna and automated buffer exchange: An interview with Unchained Labs

Scientists reclassify 200 rare immune system disorders using network-based approach

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Amgen to discuss application for LUMAKRAS® (sotorasib) for the treatment of KRAS G12C-positive NSCLC at FDA advisory committee meeting

The efficacy and safety of anti-androgens in the management of hormonal and clinical features of PCOS

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

Universal approach could potentially expand CAR T cell therapy to all blood cancers

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

Study finds semaglutide provides benefits for patients with obesity phenotype of heart failure and HFpEF

Study explores the potential of robotic-assisted TMS for depression

Fourth COVID-19 booster supercharges antibody defense in older adults, study says

ADHD drug could serve as a cocaine-replacement therapy

Engineered ACE2 decoy shows promise as COVID-19 treatment

GADx's BotrytisAlert now detects fungal crop pathogen across several critical points in wine production

Low-carbohydrate diets as strategies for improving glycemic control in diabetic patients

High-fiber diets may help control the adverse effects of antibiotic treatments on beneficial gut microbiota

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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