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Feedback loop involving estrogen linked to women's higher propensity to nicotine addiction

A newly discovered feedback loop involving estrogen may explain why women might become dependent on nicotine more quickly and with less nicotine exposure than men.

25 Mar 2024

Vitamin D receptor presence in breast cancer tumors linked to better survival outcomes

Research identifies vitamin D receptors (VDR) in breast cancer tumors as a promising prognostic marker, linking VDR presence to tumor characteristics, survival outcomes, and potentially informing treatment strategies.

25 Mar 2024

New glycan found to play a key role in nasal colonization of whooping cough bacteria

Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.

25 Mar 2024

New method predicts sepsis and organ failure in children

University of Queensland researchers have developed a method to predict if a child is likely to develop sepsis and go into organ failure.

25 Mar 2024

Nucleus Genomics ushers in a new era of personalized medicine to the public

Nucleus Genomics, the next-generation genetic testing and analysis company, today announced the launch of its DNA analysis product to bring the benefits of personalized medicine to everyone.

25 Mar 2024

MUTYH gene mutation linked to increased risk of various solid tumors

A gene associated with colorectal cancer appears to also play a role in the development of other solid tumors, according to a study of over 350,000 patient biopsy samples conducted by researchers at the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health and Foundation Medicine.

25 Mar 2024

Unraveling epigenetic contributions to autoimmune skin diseases

The central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product protein.

25 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

bioXcelerate launches breakthrough AI tool for faster drug discovery

bioXcelerate, a new and innovative health data science division of Optima Partners Limited, has revealed a new groundbreaking AI tool, which is set to accelerate the process for identifying and developing new drugs.

24 Mar 2024

Southern expansion of hemorrhagic fever virus in Sweden linked to bank voles

Researchers have discovered that bank voles in Skåne, southern Sweden, carry a virus that can cause hemorrhagic fever in humans.

22 Mar 2024

Unlocking the mysteries of early human development through blastoid models

It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for all to come.

22 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Researchers create new platform to identify proteins for targeted treatment of disease

Researchers at the University of Toronto and Sinai Health have created a new platform to identify proteins that can be co-opted to control the stability of other proteins - a new but largely unrealized approach to the treatment of disease.

22 Mar 2024

Study shows cellular, molecular overlaps in ALS and FTLD

On the surface, the movement disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and the cognitive disorder frontotemporal lobar degeneration (FTLD), which underlies frontotemporal dementia, manifest in very different ways. In addition, they are known to primarily affect very different regions of the brain.

22 Mar 2024

Boosting mRNA activity and longevity with multi-tailed structures

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

22 Mar 2024

Aging linked to length of genes, study suggests

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Scientists uncover four proteins that govern the identity of anaplastic large cell lymphoma

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma (ALCL), an aggressive form of cancer.

22 Mar 2024

Long genes linked to faster biological aging

What causes our body to age? Four complementary studies, including one from Northwestern Medicine, have come to the same conclusion: long genes.

21 Mar 2024

Researchers devise novel technique for crafting human artificial chromosomes

Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory applications, though serious technical obstacles have hindered their development.

21 Mar 2024

Groundbreaking atlas maps over 80 blood stem cell types

Thanks to an unusual application of game theory and machine learning technology, a large team of scientists led by experts at Cincinnati Children's has published the world's most detailed "atlas" of the many types of stem cells and early progenitors involved in producing human blood from diverse donors.

21 Mar 2024