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Study reveals why some germinal centers persist for months rather than weeks

If B cells are the munitions factories of the immune system, manufacturing antibodies to neutralize harmful pathogens, then the tiny biological structures known as germinal centers are its weapons-development facilities.

23 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Researchers evaluated plasma and nasal antibody titers responses induced by natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) vaccinations among United Kingdom (UK) residents.

23 Dec 2022

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.

23 Dec 2022

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

A new study evaluated the effectiveness of coronavirus disease 2019 (COVID-19) vaccines in Argentinian children when severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron were predominant.

23 Dec 2022

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

A new paper presents preliminary evidence that a new vaccine candidate, designed to boost immunity in already immunized individuals, and containing the adjuvanted Beta spike variant protein antigen, can induce a potent cross-neutralizing antibody response in non-human primate models that is detectable for up to three months.

23 Dec 2022

Children less likely to transmit infectious particles, study finds

Infectious diseases are often transmitted via particles exhaled from infected persons. Yet, the size of such aerosol particles varies greatly, depending on its origin in the respiratory tract.

22 Dec 2022

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

A recent Nature Cancer study documented that individuals with B cell lymphomas (LY) and multiple myeloma (MM) developed potent infection neutralization capabilities against several SARS-CoV-2 variants of concern (VoCs).

22 Dec 2022

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Researchers assesses the real-world efficacy of the novel bivalent COVID-19 vaccine.

22 Dec 2022

Using the gut microbiome to understand and treat respiratory diseases

Researchers review the role of the gut microbiome in certain respiratory diseases.

22 Dec 2022

Cystic fibrosis drug shows promise to treat pneumonia

Pathogens such as SARS-CoV-2 and pneumococcus can cause severe pneumonia. If the airways then fill with fluid, the patient risks developing acute respiratory distress syndrome.

22 Dec 2022

KHN’s ‘What the Health?’: The covid response coordinator speaks

Dr. Ashish Jha, the White House covid-19 response coordinator, is the guest for a wide-ranging interview on this week's "What the Health?" podcast.

22 Dec 2022

ER doctors call private equity staffing practices illegal and seek to ban them

A group of emergency physicians and consumer advocates in multiple states are pushing for stiffer enforcement of decades-old statutes that prohibit the ownership of medical practices by corporations not owned by licensed doctors.

22 Dec 2022

UK government strikes a deal with Moderna to boost mRNA research and development

Patients in the UK will be protected against potential future global health threats, including potential pandemics, thanks to a deal struck between the government and Moderna.

22 Dec 2022

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Omicron subvariants effectively escape B-cell immune responses by modifying neutralizing antibody epitopes.

21 Dec 2022

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

The study, which is currently available in the medRxiv* preprint server, reveals that the COVID-19 vaccination has prevented a large number of hospitalizations during the pandemic.

21 Dec 2022

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Researchers observe that COVID-19 patients were at an increased risk of developing certain conditions.

21 Dec 2022

Study: Long COVID has four major subtypes defined by different clusters of symptoms

The post-COVID syndrome known as long COVID has four major subtypes defined by different clusters of symptoms, according to a study led by researchers at Weill Cornell Medicine.

21 Dec 2022

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

A recent draft released by the World Health Organization discussed the new global strategy to address the gaps in infection prevention and control (IPC) programs that became apparent after the coronavirus disease 2019 (COVID-19) pandemic.

21 Dec 2022

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Researchers investigated the mechanisms through which the human common cold Betacoronavirus OC43 (HCoV-OC43) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit the formation of stress granules.

21 Dec 2022

Respiratory News and Research

Study reveals why some germinal centers persist for months rather than weeks

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Exploring plasma and nasal antibody responses to SARS-CoV-2 infection and vaccination

Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

High efficacy of SARS-CoV-2 vaccines in preventing COVID-19 deaths in children and adolescents

Beta-containing COVID-19 booster vaccine found to cross-neutralize variants in non-human primates

Children less likely to transmit infectious particles, study finds

COVID-19 vaccination protects people with B cell lymphoma and multiple myeloma

Bivalent mRNA vaccine is moderately effective in preventing COVID-19

Using the gut microbiome to understand and treat respiratory diseases

Cystic fibrosis drug shows promise to treat pneumonia

KHN’s ‘What the Health?’: The covid response coordinator speaks

ER doctors call private equity staffing practices illegal and seek to ban them

UK government strikes a deal with Moderna to boost mRNA research and development

T-cell immunity remains effective against SARS-CoV-2 Omicron subvariants

Dutch study shows the effectiveness of COVID vaccination in reducing hospitalizations

History of COVID-19 increases risk of fatigue and other long COVID symptoms in adults and children

Study: Long COVID has four major subtypes defined by different clusters of symptoms

WHO releases a global strategy for infection prevention and control at the 75th World Health Assembly

SARS-CoV-2 and human cold coronavirus OC43 inhibit stress granule formation through Nsp15 protein

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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