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Functional human blood vessels grown in mice using cells from adult human donors

For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors - an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association.

19 Jul 2008

Regular walking protects the Masai against cardiovascular disease

Scientists have long been puzzled by how the Masai can avoid cardiovascular disease despite having a diet rich in animal fats. Researchers at Karolinska Institutet believe that their secret is in their regular walking.

18 Jul 2008

FDA lifts warning on eating certain types of red raw tomatoes

The U.S. Food and Drug Administration is updating its warning to consumers nationwide concerning the outbreak of Salmonella Saintpaul.

17 Jul 2008

Breast cancer researchers call for ethnicity to be taken into account when developing treatments

Breast cancer research needs to investigate how a person's ethnicity influences their response to treatment and its outcome, according to a new Comment piece in today's Lancet by researchers from Imperial College London.

17 Jul 2008

Standards in stem cell research

Standards in stem cell research help both scientists and regulators to manage uncertainty and the unknown, according to new research funded by the Economic and Social Research Council. Efforts to standardise practices across different labs is, however, a balancing act where the autonomy of scientists and fragility of living material need to be weighed against the need for comparable data.

17 Jul 2008

Selective face processing abnormalities in parents of autistic children

Some parents of children with autism evaluate facial expressions differently than the rest of us - and in a way that is strikingly similar to autistic patients themselves, according to new research by psychiatrist Dr. Joe Piven of the University of North Carolina at Chapel Hill and neuroscientist Ralph Adolphs, Ph.D., of the California Institute of Technology.

17 Jul 2008

Gene variation increases risk of elevated triglycerides in Asians

A genetic variant found almost exclusively in individuals of Asian descent increases the risk of elevated triglycerides over four-fold, reports a comprehensive study in the August Journal of Lipid Research.

17 Jul 2008

Fred Hutchinson awarded $7.6 million to research how genetic variations influence risk of common diseases

Researchers at Fred Hutchinson Cancer Research Center have received a $7.6 million, four-year grant from the National Human Genome Research Institute to better understand the genetic and biological roots of common diseases. The Hutchinson Center is one of four U.S. research institutes to receive grants totaling about $31 million toward this effort.

17 Jul 2008

The aorta is torn apart in Marfan syndrome

A severe complication of the Marfan syndrome is that the aorta may split and be torn apart. The patient can be protected if the syndrome is diagnosed and treated in good time.

17 Jul 2008

Genetic resistance to HIV

Some people may be naturally resistant to infection with HIV, the virus that causes AIDS. The results of a study conducted by Dr. Nicole Bernard of the Research Institute of the McGill University Health Centre (MUHC) bring us closer to a genetic explanation. Her study findings were published on July 16 in the journal AIDS.

17 Jul 2008

Using genetics to improve traditional psychiatric diagnoses

Psychiatry has begun the laborious effort of preparing the DSM-V, the new iteration of its diagnostic manual. In so doing, it once again wrestles with the task set by Carl Linnaeus, to "cleave nature at its joints." However, these "joints," the boundaries between psychiatric disorders, such as that between bipolar disorder and schizophrenia, are far from clear. Prior versions of DSM followed the path outlined by Emil Kraeplin in separating these disorders into distinct categories. Yet, we now know that symptoms of bipolar disorder may be seen in patients with schizophrenia and the reverse is true, as well.

17 Jul 2008

Shared gene expression alterations in schizophrenia and bipolar disorder

Both schizophrenia and bipolar disorder can be disabling conditions, and both present clinically with significant mood and psychotic symptoms. These two illnesses also share genetic variants that might be involved in the predisposition to both disorders.

17 Jul 2008

Gene variant increases HIV risk in Africans

A genetic variation which evolved to protect people of African descent against malaria has now been shown to increase their susceptibility to HIV infection by up to 40 per cent, according to new research. Conversely, the same variation also appears to prolong survival of those infected with HIV by approximately two years.

17 Jul 2008

New British consortium to tackle healthcare associated infections

Just over 8% of all hospital inpatients in England develop a healthcare associated infection, with this figure rising to 23% in intensive care units. Preventing and controlling the transmission of infection is a key priority for those involved in healthcare.

16 Jul 2008

Cure for bird flu a step closer

Scientists and researchers have taken a big step closer to a cure for the most common strain of avian influenza, or "bird flu," the potential pandemic that has claimed more than 200 lives and infected nearly 400 people in 14 countries since it was identified in 2003.

15 Jul 2008

Researchers finds further evidence for genetic contribution to autism

Some parents of children with autism evaluate facial expressions differently than the rest of us--and in a way that is strikingly similar to autistic patients themselves, according to new research by neuroscientist Ralph Adolphs of the California Institute of Technology and psychiatrist Joe Piven at the University of North Carolina at Chapel Hill.

15 Jul 2008

Possible link found between X-rays and prostate cancer

Researchers at The University of Nottingham have shown an association between certain past diagnostic radiation procedures and an increased risk of young-onset prostate cancer - a rare form of prostate cancer which affects about 10 per cent of all men diagnosed with the disease.

15 Jul 2008

New understanding of fetal hemoglobin regulation in patients with sickle cell disease

Although sickle cell disease is a single-gene disorder, its symptoms are highly variable. In a study published online July 14 by the Proceedings of the National Academy of Sciences, scientists at Children's Hospital Boston and the Dana Farber Cancer Institute (DFCI), in collaboration with the Broad Institute of MIT and Harvard, report five gene variants that could potentially be helpful in predicting sickle cell disease severity, perhaps even leading to better treatment approaches in the future.

15 Jul 2008

"Smothered" genes combine with mutations to yield poor out come in cancer patients

Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients.

15 Jul 2008