Genetic News and Research

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Guidelines to prevent genetic discrimination

A multi-disciplinary group from Stanford University (California, US) has proposed ten principles to guide the use of racial and ethnic categories in genetic research, as reported today in BioMed Central's open access journal Genome Biology.

15 Jul 2008

An inflamed response

Paul Martin, Professor of Cell Biology in the University of Bristol Departments of Physiology and Pharmacology, and Biochemistry, talked to Cherry Lewis about the discovery made in his lab that speeds up wound healing and reduces the size of the wound scar. She was interested not only in the discovery itself, but also in the processes and years of research that led up to it.

15 Jul 2008

Variations in the serotonin transporter gene may determine who responds best to antidepressant

A new Mayo Clinic study shows that variations in the serotonin transporter gene could explain why some people with depression respond better than others to treatment with citalopram (Celexa), an antidepressant medication.

14 Jul 2008

Huntington's disease brain damage linked to overactive immune response in the bloodstream

The damage to brain tissue seen in Huntington's disease may be caused by an overactive immune response in the bloodstream and the brain, according to new findings from two teams of researchers at the University of Washington in Seattle and University College London. The findings will be published online July 14 in the Journal of Experimental Medicine.

14 Jul 2008

Apert's syndrome - new discovery

In a cruel irony, testis cells carrying the mutation that causes Apert's syndrome are fitter than normal cells, even though children born from sperm derived from those cells are weakened by fused fingers, toes and skulls, a new study has found.

14 Jul 2008

Incorrectly cleaved protein leads to schizophrenia

Schizophrenia is a disease that strikes an average of 4,000 Belgians every year. The causes of this psychiatric disorder are not yet clear.

14 Jul 2008

Susceptibility to pain is affected by premature birth and also genetics

Scientists in US and UK laboratories have made key discoveries into the elusive nature of pain in children and adults. The results, presented at the Forum of European Neurosciences Monday will help guide the future management and treatment of pain.

14 Jul 2008

Brain switch provides clues to drug addiction

In the quest to find the biological route of drug addiction, research at Cambridge University, UK, is revealing what makes some people more vulnerable than others. Speaking at Europe's major neuroscience conference in Geneva, Professor Barry Everitt described what they now believe causes the switch from occasional, 'recreational' use to a compulsive habit.

14 Jul 2008

Optimism is good for heart health, at least among men, a new study shows

University of Rochester Medical Center researcher Robert Gramling, M.D., D.Sc., found that men who believed they were at lower-than-average risk for cardiovascular disease actually experienced a three times lower incidence of death from heart attacks and strokes.

14 Jul 2008

Researchers locate and image prostate cancer as it spreads to lymph nodes

Using an engineered common cold virus, UCLA researchers delivered a genetic payload to prostate cancer cells that allowed them, using Positron Emission Tomography (PET), to locate the diseased cells as they spread to the lymph nodes, the first place prostate cancer goes before invading other organs.

13 Jul 2008

Discover of key patterns in gene packaging

Although every cell of our bodies contains the same genetic instructions, specific genes typically act only in specific cells at particular times. Other genes are "silenced" in a variety of ways. One mode of gene silencing depends upon the way DNA, the genetic material, is packed in the nucleus of cells.

13 Jul 2008

Common genetic variations increase risk of life-long nicotine addiction for young smokers

Common genetic variations affecting nicotine receptors in the nervous system can significantly increase the chance that European Americans who begin smoking by age 17 will struggle with life-long nicotine addiction. Published July 11 in the open-access journal PLoS Genetics, this research - led by scientists at the University of Utah together with colleagues from the University of Wisconsin - highlights the importance of preventing early exposure to tobacco through public health policies.

13 Jul 2008

Pandemic mutations in bird flu revealed

Scientists have discovered how bird flu adapts in patients, offering a new way to monitor the disease and prevent a pandemic, according to research published in the August issue of the Journal of General Virology.

13 Jul 2008

URMC, FDA to collaborate on national data repository for heart research

The University of Rochester Medical Center (URMC) will collaborate with the U.S. Food and Drug Administration (FDA) to develop a national repository of data that will aid academic and industry researchers studying the electrical activity of the heart. In addition to helping researchers understand many cardiac problems, the data may aid the development of new tools to detect drugs that can have dangerous effects on the heart.

13 Jul 2008

Researchers find six genes that, when mutated, contribute to autism

The hunt for gene mutations that contribute to autism has proceeded slowly, largely because autism encompasses a spectrum of diseases. Just as its symptoms vary widely among individuals, so do the genetic mutations that cause them.

10 Jul 2008

Common mechanisms may underlie autism's diverse mutations

Many of the seemingly disparate mutations recently discovered in autism may share common underlying mechanisms, say researchers supported in part by the National Institute of Mental Health (NIMH), a part of the National Institutes of Health (NIH). The mutations may disrupt specific genes that are vital to the developing brain, and which are turned on and off by experience-triggered neuronal activity.

10 Jul 2008

Advances in RNA research

RNA, the transporter of genetic information within the cell, has emerged from the shadow of DNA to become one of the hottest research areas of molecular biology, with implications for many diseases as well as understanding of evolution. But the field is complex, requiring access to the latest equipment and techniques of imaging, gene expression analysis and bioinformatics, as well as cross-pollination between multiple scientific disciplines.

10 Jul 2008

Lipid Association responds to new cholesterol guidelines for kids

When the American Academy of Pediatrics (AAP) issued its recommendation on July 7 regarding the treatment of children with high cholesterol, it generated a strong response from the community of medical professionals and patients. The National Lipid Association (NLA), a group of healthcare professionals who specialize in cholesterol and heart disease issues, believes that the AAP has acted in the interests of patient care by raising the issue of lipid abnormalities in children.

10 Jul 2008

A micro-sized sewing machine for DNA

Japanese scientists have made a micro-sized sewing machine to sew long threads of DNA into shape. The work published in the Royal Society of Chemistry journal Lab on a Chip demonstrates a unique way to manipulate delicate DNA chains without breaking them.

10 Jul 2008

Scientists generate the most precise map of genetic recombination ever

Genetic recombination, the process by which sexually reproducing organisms shuffle their genetic material when producing germ cells, leads to offspring with a new genetic make-up and influences the course of evolution.

10 Jul 2008