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Sweetener saccharin revives old antibiotics by breaking bacterial defences

Saccharin destabilizes bacterial membranes and interferes with DNA replication, causing lysis and impairing virulence traits. The sweetener also re-sensitizes multidrug-resistant pathogens to antibiotics and disrupts stubborn biofilms.

3 Apr 2025

Many people with disabilities risk losing their Medicaid if they work too much

Zach Mecham has heard politicians demand that Medicaid recipients work or lose their benefits. He also has run into a jumble of Medicaid rules that effectively prevent many people with disabilities from holding full-time jobs.

25 Mar 2025

Children with complicated appendicitis can safely recover at home after surgery

Almost half of children who require surgery for complicated appendicitis can safely complete their recovery at home, according to a new study.

20 Mar 2025

Checking the facts on Medicaid use by Latinos

Spending cuts, immigration, and Medicaid are at the top of the Washington agenda. That climate provides fertile ground for misinformation and myths to multiply on social networks.

17 Mar 2025

TUM scientists develop new protein purification method using UV light

Proteins play a key role in the life sciences - from basic research and biotechnological applications to the development and manufacturing of pharmaceuticals.

5 Mar 2025

Key research priorities for understanding and treating appendiceal cancer

Appendiceal cancer is a rare cancer without standardized screening guidelines, risk factors or tumor classifications - a situation that often results in late diagnosis and poor prognosis.

21 Feb 2025

Study reveals drastic variations in U.S. health care spending across counties

Researchers present the most comprehensive study on U.S. health care spending and variations across 3,110 counties by four payers, 148 health conditions, 38 age/sex groups, and seven types of care.

14 Feb 2025

Global Commission proposes new framework for obesity diagnosis and treatment

A global Commission, published in The Lancet Diabetes & Endocrinology and endorsed by 75 medical organizations around the world, presents a novel, nuanced approach to diagnose obesity, based on other measures of excess body fat in addition to body mass index (BMI), and objective signs and symptoms of ill health at the individual level.

15 Jan 2025

Global study reports significant decline in diarrheal disease mortality

New global study reports a 60% drop in global mortality from diarrheal diseases, but children and the elderly still have the highest death rates, particularly in sub-Saharan Africa and South Asia.

19 Dec 2024

Removing a splinter? Treating a wart? If a doctor does it, it can be billed as surgery

When George Lai of Portland, Oregon, took his toddler son to a pediatrician last summer for a checkup, the doctor noticed a little splinter in the child's palm.

13 Dec 2024

Study reveals stark life expectancy disparities across the United States

Life expectancy in the USA varies by more than 20 years depending on an individual's race and ethnicity and where they live.

22 Nov 2024

Obesity crisis in the U.S. expected to worsen by 2050

Over the past three decades, there has been a startling increase in the prevalence of obesity across the USA, at least doubling in adult men and women (aged 25 and older) and older female and male adolescents (aged 15-24 years) since 1990, with the number of people living with overweight and obesity reaching over 208 million in 2021 - a trend set to continue in the coming decades without significant reform, according to a major new analysis from the Global Burden of Disease Study Collaborator Network, published in The Lancet.

15 Nov 2024

Advances in the surgical management of gastroschisis

Gastroschisis, a congenital abdominal wall defect, has transformed from a uniformly fatal condition to one with a 95% survival rate through surgical advancements over the past six decades.

8 Nov 2024

New toolkit aims to help U.S. hospitals spot deadly viral hemorrhagic fevers faster and safer

Researchers develop a laboratory toolkit to assist frontline healthcare facilities or the care of patients with suspected viral hemorrhagic fevers.

30 Oct 2024

FDA-approved breast cancer drug shows promise for appendix cancer

Researchers at University of California San Diego School of Medicine found an FDA-approved drug used to treat breast cancer has the potential to be an effective therapeutic for a specific type of appendix cancer.

16 Oct 2024

Creating a tobacco-free generation could prevent 1.2 million lung cancer deaths

Creating a generation of people who never smoke could prevent 1.2 million deaths from lung cancer globally, according to a study led by researchers from the University of Santiago de Compostela, the International Agency for Research on Cancer (IARC), and global collaborators published in The Lancet Public Health journal.

3 Oct 2024

Study highlights disparities in stroke burden across regions

Although stroke is highly preventable and treatable, there has been a rapid rise in the global stroke burden between 1990 and 2021, due to both population growth and the rise of aging populations worldwide, as well as a substantial increase in people's exposure to environmental and behavioral risk factors.

19 Sep 2024

Antibiotic resistance threatens millions of lives worldwide

More than 39 million people around the world could die from antibiotic-resistant infections over the next 25 years, according to a study published in The Lancet.

18 Sep 2024

Evaluating underwater endoscopic mucosal resection for gastrointestinal neuroendocrine tumors

Neuroendocrine tumors (NETs) of the gastrointestinal (GI) tract are a rare and heterogeneous group of malignancies arising from the neuroendocrine cell system.

4 Sep 2024

Research may pave the way for systemic targeted therapy for patients with pseudomyxoma peritonei

Published in Clinical Cancer Research, results of a preclinical study led by investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Stem Cells and Cancer Group, headed by Héctor G. Palmer, pave the way for systemic targeted therapy in patients with pseudomyxoma peritonei, a rare form of cancer with very few therapeutic options available.

19 Jul 2024