Azithromycin News and Research

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Azithromycin, also known as Zithromax, belongs to the class of medicines known as antibacterials orantibiotics. These medicines kill bacteria (small organisms that can cause infection in humans) or stopbacteria from growing. Patients with weakened immune systems, includingpeople with HIV, tend to have more frequent andmore serious bacterial infections. Azithromycinwas approved by the FDA on June 14, 1996, formany uses, including the prevention and treatmentof Mycobacterium avium complex (MAC) inpersons with advanced HIV infection. It is alsobeing investigated to see how well it works inpreventing other kinds of bacterial infections inpeople with HIV.

Study identifies how zinc deficiency can make drug-resistant bacteria vulnerable

Researchers at McMaster University have discovered a critical vulnerability in drug-resistant bacteria: zinc - or a lack thereof.

6 Jan 2025

Emergence of FC428 clone and the global spread of ceftriaxone-resistant gonorrhea

Neisseria gonorrhoeae, responsible for the sexually transmitted infection gonorrhea, is becoming increasingly difficult to treat as the pathogen has developed resistance to multiple antibiotics.

30 Dec 2024

Scientists reveal the spread of highly drug-resistant cholera strain

Scientists from the National Reference Center for Vibrios and Cholera at the Institut Pasteur, in collaboration with the Centre hospitalier de Mayotte, have revealed the spread of a highly drug-resistant cholera strain.

14 Dec 2024

Study aims to reduce C-section rates in pregnant women with obesity

Pregnant women with obesity face an increased risk of complications, including the need for a cesarean section, which carries its own set of risks.

6 Nov 2024

WHO confirms elimination of trachoma in South Asia

The world moved closer to eliminating trachoma this month after the World Health Organization (WHO) confirmed India and Pakistan as being free of the disease, a leading cause of blindness.

16 Oct 2024

Study highlights rising rates of tick-borne parasitic disease in the United States

Rates of babesiosis, a tick-borne parasitic disease, increased an average of 9% per year in the United States between 2015 and 2022 and four in 10 patients were found to be co-infected with another tick-borne illness such as Lyme disease, according to a new study led by researchers at Penn State Health Milton S. Hershey Medical Center and Penn State College of Medicine.

8 Oct 2024

New tool spots drug-resistant bacteria before treatment

Penicillin was hailed as "the silver bullet" when it was discovered, as it had the unprecedented quality of being able to kill disease-causing bacteria without harming the human body. Since then, a multitude of other antibiotics have been developed that specifically target a wide range of bacteria; but the more often they are used, the greater the risk that antibiotic-resistant strains will arise.

19 Sep 2024

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Researchers assess the airway microbiome and host immune-inflammatory responses to identify treatable aspects of severe asthma.

17 Sep 2024

Cardiovascular risks of COVID-19 antivirals

Study reviews cardiovascular side effects linked to antiviral therapies for COVID-19, highlighting the need for careful consideration when prescribing these drugs to high-risk patients.

16 Sep 2024

Expanded use of common antibiotic cuts child mortality by 14% in Sub-Saharan Africa

When UC San Francisco research showed that routinely treating children in Sub-Saharan Africa with a common antibiotic could reduce deaths in children under five, the World Health Organization (WHO) moved quickly to recommend the treatment – but only for infants between 1 and 11 months old.

22 Aug 2024

Many children with recurrent wheezing have "silent" lung infections, research reveals

Nearly a quarter of children with recurrent wheezing have "silent" lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals.

8 Aug 2024

Analysis finds significant variations in national COVID-19 treatment recommendations

National clinical guidelines for the treatment of COVID-19 vary significantly around the world, with under-resourced countries the most likely to diverge from gold standard (World Health Organization; WHO) treatment recommendations, finds a comparative analysis published in the open access journal BMJ Global Health.

23 Apr 2024

ChatGPT could be an effective tool to help reduce vaccine hesitancy

New research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, by improving knowledge and access to care.

10 Apr 2024

Rising antimicrobial resistance in STIs: A call for global action

Review delves into the rising challenge of antimicrobial resistance in sexually transmitted infections, underscoring the need for innovative treatments and the critical role of global surveillance in managing diseases like gonorrhea and syphilis.

21 Mar 2024

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

Oral azithromycin reduces maternal sepsis and healthcare costs in low-resource settings

Sepsis, a severe infection that can lead to tissue damage, organ failure, and death, is one of the top three causes of maternal deaths worldwide, according to the World Health Organization.

12 Feb 2024

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

9 Feb 2024

Gonorrhea cases surge 64% post-COVID lockdown in England, highlighting unintended STI suppression

A study analyzing data from the Genitourinary Medicine Clinic Activity Dataset in England shows a 64% increase in gonorrhea diagnoses following the relaxation of COVID-19 restrictions, despite only a 5.6% increase in STI testing, suggesting that social distancing may have suppressed STI transmission.

4 Jan 2024

Alarming rise in antibiotic-resistant urogenital infections in Greece, study shows escalating resistance trends

The trends in antimicrobial resistance in Greece.

1 Dec 2023

Antibiotics that target mitochondria may promote longevity

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 21, entitled, "Antibiotics that target mitochondria extend lifespan in C. elegans."

22 Nov 2023