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ESMO updates precision oncology framework to improve targeted therapies

ESMO has published version 2 of the ESMO Scale for Clinical Actionability of molecular Targets (ESCAT), a major update to the internationally recognized precision oncology framework that helps oncologists assess the clinical relevance of molecular alterations and match patients with the most appropriate targeted therapies.

22 Oct 2026

Cell Painting method reveals drug differences in 3D cancer cells

Researchers at Uppsala University have adapted Cell Painting, a widely used imaging method in drug discovery, to look at individual cells inside small 3D clusters of cancer cells.

21 Oct 2026

Oxaloacetate supplement may help reduce chemo brain in breast cancer survivors

A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that a nutritional supplement containing oxaloacetate, a molecule naturally found in the body that helps cells produce energy, may help improve cognitive function and reduce the fatigue experienced by some breast cancer survivors following treatment.

21 Oct 2026

Most frail breast cancer survivors lack Medicare home care

For the increasing number of women that survive breast cancer, many older, long-term survivors remain frail. A new study out today in the Journal of the National Cancer Institute shows that in a given year over half of these highly frail survivors had no Medicare home health care.

20 Oct 2026

Liquid biopsy reliably detects early-stage lung cancer recurrence risk

Despite advances in early-stage lung cancer treatment, a significant number of patients experience disease recurrence after surgery or initial therapy.

20 Oct 2026

Scientists discover immune pathway behind radiation-induced lung damage

Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the country, have uncovered an immune pathway that may contribute to radiation-related lung damage and have identified a potential strategy to block it.

20 Oct 2026

New gene-editing platform gives doctors control over cell therapies

An Australian clinician-led research team has developed a gene-editing platform that could give doctors more control over cell therapies, making them more practical for patients with complex immune conditions.

20 Oct 2026

First patient dosed in Phase 1 clinical trial of new cancer drug

On August 18, 2026, in Japan, the Department of New Experimental Therapeutics and Early-Phase 1 Drug Development Service at Kansai Medical University Hospital, led by Professor Toshio SHIMIZU, administered DS1025 to the first patient worldwide as part of a global, multicenter First-in-Human Phase 1 clinical trial sponsored by Daiichi Sankyo.

19 Oct 2026

Invisible no more: New treatment avenue unlocked for deadliest lung cancer

Researchers have uncovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, the most aggressive form of the disease globally.

16 Oct 2026

Blood Cancer United awards grant to diversify clinical trial access

Blood Cancer United, formerly The Leukemia & Lymphoma Society, has awarded $2.5 million to a research team led by Melissa Beauchemin, Ph.D., Assistant Professor at Columbia University School of Nursing, through its Equity in Access Research Program.

15 Oct 2026

WEHI study reveals a new immune pathway for fighting small cell lung cancer

Researchers have uncovered a previously overlooked immune cell that can recognize and kill small cell lung cancer, the most aggressive form of the disease globally.

14 Oct 2026

Developing biomaterials for soft tissue reconstruction

Explore how biomaterials and additive manufacturing support medical device development for soft tissue reconstruction.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 13 Oct 2026

Childhood leukemia treatment causes rapid, lasting challenges for patient families

New research in the October 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that families of children receiving treatment for B-cell acute lymphoblastic leukemia (B-ALL) experience substantial and lasting challenges beginning early after diagnosis, according to a new multicenter study embedded in a Children's Oncology Group (COG) trial.

13 Oct 2026

Long non-coding RNAs offer new pathways to overcome cancer treatment resistance

Scientists are highlighting long non-coding RNAs (lncRNAs) as promising targets in the effort to overcome one of cancer treatment's most persistent challenges: therapeutic resistance.

12 Oct 2026

RNA modification enzyme FTO shows therapeutic promise in gastrointestinal cancers

A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially important biomarker and therapeutic target across gastrointestinal cancers.

12 Oct 2026

Global survey finds gaps in pediatric cardiac troponin testing

Cardiac troponin, a protein released into the blood when heart muscle is damaged, can be used as a quick measure of heart injury in adults, and testing for it has revolutionized adult cardiology. For children, however, doctors often lack data on normal troponin measurements.

9 Oct 2026

FDA approves atezolizumab combination for stage III colon cancer with deficient DNA mismatch repair

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has approved the immunotherapy drug atezolizumab (Tecentriq) in combination with fluoropyrimidine and oxaliplatin chemotherapy, for the adjuvant treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

9 Oct 2026

NCCN collaborates with global organizations to launch tailored cancer guidelines for Philippines

The National Comprehensive Cancer Network (NCCN)-an alliance of leading academic cancer centers in the United States-is collaborating with several global organizations to publish new International Adaptations of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for the Philippines.

8 Oct 2026

Universal germline genetic testing catches missed cancer risks in older patients

Universal germline genetic testing of nearly 40,000 patients with solid tumors detected a substantial proportion of inherited gene variants that would have been missed by the standard germline testing approach that excludes those over age 50.

8 Oct 2026

A New Approach to Preventing Bladder Cancer Recurrence

Innovative techniques using electrical energy to treat bladder cancer may lower recurrence rates and minimize the need for radical surgical interventions.

8 Oct 2026