Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

A striking immune cell pattern emerges around a person’s 100th birthday

Single-cell immune profiling found that CD4 cytotoxic T lymphocytes become more abundant around age 100, showing stepwise differentiation and substantial clonal expansion. Ex vivo experiments also revealed cytokine plasticity within individual clones, supporting the hypothesis that these cells adapt to persistent antigens during healthy aging, although their direct role in longevity remains unproven.

23 Aug 2026

Computational pipeline uncovers subtype specific targets for cervical cancer

A new study presents a multi-layered strategy for identifying cell-surface targets that could help guide more precise antibody-drug conjugate (ADC) development for cervical cancer, with different targets showing distinct potential across tumor subtypes.

17 Aug 2026

AI model predicts cancer subtype, genetic mutations, and survival outcomes across 32 solid tumors

Researchers have developed a novel AI model that can analyze a routine whole histopathology image and simultaneously predict cancer subtype, specific genetic mutations, and survival outcomes across 32 different solid cancers rather than focusing on a single cancer type.

13 Aug 2026

AI-based methods help uncover hidden roots of tumor metastasis

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways.

12 Aug 2026

Researchers develop noninvasive chairside test to detect oral cancer

A Case Western Reserve University–led research team is developing a noninvasive oral cancer test to help clinicians decide-chairside and within minutes- whether a suspicious lesion in the mouth needs a biopsy.

12 Aug 2026

Combination therapy overcomes ferroptosis resistance in β-catenin-mutant hepatocellular carcinoma

The aberrant activation of the mTOR pathway and its crosstalk with other signaling cascades represent key drivers of hepatocellular carcinoma (HCC) progression. mTOR-mediated ferroptosis suppression has been implicated in HCC resistance to chemotherapy.

7 Aug 2026

Piezo ion channels: Key regulators of digestive health and disease

Mechanosensitive Piezo ion channels, particularly Piezo1 and Piezo2, are gaining recognition as central regulators of digestive system physiology and disease.

7 Aug 2026

Tuft cell-like cancers exhibit unique biological characteristics across multiple organs

A growing body of evidence suggests that a rare epithelial cell type known as the tuft cell may play a far more significant role in cancer than previously recognized.

6 Aug 2026

Scalable education program protects transplant survivors from elevated skin cancer risk

Experts at City of Hope, one of the nation's largest and most advanced cancer research and treatment organizations, are shining a spotlight on the risk of skin cancer faced by hematopoietic cell transplant (HCT) survivors, as well as the need for early detection.

6 Aug 2026

Study identifies a novel direct drug target for head and neck squamous cell carcinoma

Chemotherapy remains a cornerstone of treatment for head and neck cancers, the seventh-most common cancer type worldwide.

6 Aug 2026

Experimental drug CS18 shows promise for overcoming cancer treatment resistance

Researchers at Baylor College of Medicine have developed a drug called CS18 that disrupts the ability of cancer cells to survive therapy. The findings, published in Science Advances, support exploring the possibility of using CS18 to treat human cancer in the future.

5 Aug 2026

Obscure X chromosome protein emerges as key driver in several cancers

A little-known protein encoded on the X chromosome is attracting growing attention for its potential role in cancer development and treatment.

5 Aug 2026

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the publication of a collaborative study in the journal npj Precision Oncology.

4 Aug 2026

Daily tomatoes lowered a key marker of liver fat in MASLD trial

An exploratory randomized trial found that 200 g of raw tomatoes plus 50 g of tomato sauce daily for six weeks produced a greater reduction in CAP-defined hepatic steatosis than a tomato-free diet in adults with MASLD. The improvement occurred without major weight or metabolic changes, but larger and longer trials are needed to confirm its clinical significance.

2 Aug 2026

AI-powered blood test detects liver cancer across distinct populations

Researchers at the Johns Hopkins Kimmel Cancer Center validated an artificial intelligence (AI)-powered blood test that accurately detected liver cancer in people from two geographically and biologically distinct populations and also uncovered the underlying biological signals that make the test effective.

31 Jul 2026