Cardiometabolic News and Research

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High-fiber diet beats metformin for blood sugar and weight in trial

High-fiber diet improves blood sugar and weight more than metformin in a small diabetes trial.

7 Oct 2026

Study links pregnancy complications to future heart and kidney disease

Women with a complication in the latest pregnancy, or in a previous pregnancy, face an elevated risk of developing cardiometabolic-renal conditions in subsequent years, suggests a UK study published online in the open access journal BMJ Medicine.

6 Oct 2026

Long-term "Food Is Medicine" program improves cardiometabolic health in adults

Providing people with nutritious foods can improve the management of chronic metabolic diseases such as type 2 diabetes and hypertension.

5 Oct 2026

CBL-514 injection reduces visceral and subcutaneous fat in trials

Details of a new injection that targets fat cells will be released at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2).

1 Oct 2026

Sex chromosomes influence immunity, cancer, aging and disease risk

A new review published in Science brings together growing evidence that the X and Y chromosomes do much more than determining biological sex. They also shape how cells function, age and respond to disease.

1 Oct 2026

Overall dietary patterns matter more for heart health than nutrients

A healthy, balanced dietary pattern, rather than one focused on individual nutrients or foods is key to maintaining heart health, according to a Scientific Statement issued by the American College of Cardiology and published in JACC, its flagship journal.

30 Sep 2026

Novo Nordisk Foundation funds genomic research into metabolic diseases

The Novo Nordisk Foundation has committed $53 million to renew and expand the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease at the Broad Institute, led by managing director Kasper Lage.

30 Sep 2026

Petrelintide produces double-digit weight loss with fewer side effects

New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Diabetes & Endocrinology shows that weekly injections with the new amylin-based obesity drug petrelintide can enable those treated to lose more than 10% of their body weight – generally lower than existing incretin-based (GLP-1 RA) drugs, but also with far fewer side effects.

29 Sep 2026

First EU Screening Week urges citizens to know their numbers

At a dedicated press conference at the EASD Annual Meeting in Milan, organized by the European Diabetes Forum (EUDF), three leading European cardiometabolic scientific associations - the European Society of Cardiology (ESC), the European Association for the Study of Diabetes (EASD) and the European Association for the Study of Obesity (EASO) - joined European Commissioner for Health and Animal Welfare Olivér Várhelyi to welcome the launch of the first-ever EU Screening Week.

29 Sep 2026

From espresso to filter coffee, brewing may shape what reaches your gut

A focused narrative review traces how caffeine, chlorogenic acids, and coffee fibers move through the gut and interact with microbes. The authors identify plausible links between the microbiome and liver health, but human studies have not shown that microbiome changes cause coffee’s reported metabolic benefits.

28 Sep 2026

Neurodivergent youth face higher risk of early-onset type 2 diabetes

People with neurodiversity, particularly autism and ADHD (attention-deficit/hyperactivity disorder), may be more likely to be diagnosed with type 2 diabetes (T2D) at younger ages, with particularly high prevalence of neurodiversity observed among individuals diagnosed with T2D before the age of 20, finds an analysis of patient data being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy (September 28–October 2.

27 Sep 2026

Could the Mediterranean diet protect the brain through the gut?

A narrative review finds that the Mediterranean diet may support brain health through gut microbiome, immune, metabolic, and barrier-related pathways, but direct human evidence that microbiome remodeling mediates neuroprotection remains limited. The proposed mechanisms involve microbial metabolites, reduced inflammatory signaling, stronger intestinal and blood-brain barrier function, and possible effects on processes linked to Alzheimer’s and Parkinson’s diseases.

27 Sep 2026

Intuitive eating may be linked to more than a healthier relationship with food

A cross-sectional study of 1,057 U.S. adults examined how intuitive eating relates to stress, sleep, physical activity, substance use, diet, self-rated health, and self-reported cardiometabolic conditions. Higher intuitive eating scores were associated with several favorable health indicators, although the study cannot establish causality or determine the direction of these relationships.

25 Sep 2026

Semaglutide’s heart benefits may extend beyond weight loss

Semaglutide is known to reduce the risk of serious heart disease. However, a new study published in the European Heart Journal today (Thursday) suggests that this effect cannot not be entirely explained by patients losing weight on the drug.

23 Sep 2026

Menopause leaves a blood protein signature linked to brain aging and Alzheimer’s risk

Researchers identified a 16-protein blood signature associated with menopause that tracked more strongly with reproductive hormones than chronological age and was largely replicated in an independent UK Biobank cohort. Higher menopause proteomic scores were also associated with less favorable proteomic aging estimates and poorer cognitive outcomes in older women, including incident Alzheimer’s dementia, although the observational evidence does not establish causality.

23 Sep 2026

Early childhood BMI trajectories predict later cardiometabolic health risks

Childhood obesity predicts later cardiometabolic disease, but single-time weight measures may miss dynamic growth information.

23 Sep 2026

Childhood trauma linked to risky health behaviors in late adolescence

Experiencing childhood trauma appears to increase a young person's likelihood of smoking, substance use and developing unhealthy eating habits by contributing to behavioral problems during adolescence, such as impulsivity and poor self-control.

22 Sep 2026

Siemens Healthineers and Novo join forces to advance care for people living with MASLD and MASH

Siemens Healthineers and Novo have announced a collaboration focused on advancing care for people living with metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH).

From Siemens Healthineers 22 Sep 2026

Children who ate healthier plant foods had slightly lower blood pressure later

Researchers followed 3,990 Dutch children for an average of 1.6 years and found that higher healthful plant-based diet scores were associated with modestly lower blood pressure and total cholesterol. Children with higher unhealthful plant-based diet scores had lower estimated food costs and distinct metabolite profiles, while healthful scores showed no clear cost association.

22 Sep 2026

Regular exercisers show distinct metabolic and immune signatures in blood

Researchers compared blood samples from 40 regular exercisers and 46 sedentary adults and found differences in metabolites, blood chemistry, and immune cell gene activity. The patterns suggested greater fatty acid use and altered immune signaling among exercisers, but the study could not establish that exercise caused these differences.

21 Sep 2026