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Study explains why current BET inhibitors fail in cancer treatment

For over a decade, a class of drugs called BET inhibitors has been tested in cancer trials with high expectations.

9 Apr 2026

Heart failure and atrial fibrillation share underlying genetic and molecular mechanisms

New research published in Nature Cardiovascular Research reveals that heart failure and atrial fibrillation share underlying genetic and molecular mechanisms, suggesting that the two cardiovascular conditions may be less distinct than previously thought.

26 Mar 2026

Scientists win awards for the discovery of genomic imprinting and tumor’s power grid

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

13 Mar 2026

Study reveals poxvirus's unique DNA clamp for gene activation

A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation.

18 Feb 2026

Herpes virus infection softens cell nuclei through internal mechanical changes

A recent international research project has used advanced microscopy techniques and computational modeling to discover why virus infection changes the nuclear structures and biomechanical forces affecting the nucleus.

3 Feb 2026

DNA repair enzyme failure triggers inflammation and accelerates aging in cells

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic.

30 Jan 2026

Physical behavior reveals aggressive cancer cells in a simple new approach

New study shows that aggressive cancer cells can be identified in a simple, new way; by how they physically behave, not just by their genes.

26 Jan 2026

MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors

The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system.

23 Jan 2026

Researchers decipher a key mechanism that controls pancreatic cancer growth

Could this mark a shift in how we think about cancer therapy? At least in the laboratory, evidence suggests it may be.

22 Jan 2026

Atypical mutation offers clues to personalized pancreatic cancer treatment

A new study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene mutation behaves differently from other variants.

20 Jan 2026

Giant amoeba-infecting viruses offer new clues to the origin of eukaryotic life

The origin of life on Earth becomes even more fascinating and complex as we peer into the mysterious world of viruses.

8 Jan 2026

DNA twisting controls how cells respond to estrogen

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the body changes so much during menopause. This is because estrogens regulate hundreds of genes.

19 Dec 2025

Researchers discover the enzyme responsible for chromothripsis in cancer

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer cells to rapidly evolve and become resistant to treatment.

11 Dec 2025