Chest Pain News and Research

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Patient intuition leads to urgent open-heart surgery at NYU Langone Hospital—Brooklyn

Shana Hale, a Brooklyn mother of two and a technology executive, noticed a mild burning sensation in her chest during her daily walks last summer.

20 May 2026

Silent heart attacks may speed cognitive decline

Research shows hidden heart attacks accelerate cognitive decline, highlighting the need for better identification of cardiovascular risks to brain health.

18 May 2026

Study improves prediction of dangerous outcomed from hypertrophic cardiomyopathy

A sweeping international study has identified ways to detect patients who are at serious risk of sudden death, heart failure or other dangerous outcomes from heart thickening known as hypertrophic cardiomyopathy.

13 May 2026

Drug-coated balloons reduce the need for permanent heart stents

A new sub-study suggests that using a sirolimus-eluting balloon (SEB), a drug-coated balloon, can reduce the number of stents a patient may need, making it a safe and effective way to treat certain heart attacks or unstable chest pain.

23 Apr 2026

Early treatment helps patient recover from rare kidney disorder

When Bradley Lawrence gained 25 pounds in two weeks and started experiencing chest pain and shortness of breath, he quickly sought care at NYU Langone Hospital—Brooklyn.

31 Mar 2026

Deferring PCI before TAVR shows comparable outcomes in elderly patients

Older patients with coronary artery disease scheduled for transcatheter aortic valve replacement (TAVR) had comparable outcomes regardless of whether they underwent percutaneous coronary intervention (PCI) before TAVR, according to findings from the PRO-TAVI study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Trial shows mavacamten benefits adolescents with obstructive heart condition

Adolescent patients with obstructive hypertrophic cardiomyopathy (HCM) who received the drug mavacamten saw a significant improvement in left ventricular outflow tract (LVOT) gradient, a measure of blood flow obstruction in the heart, compared with those who received a placebo, according to a small study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Left-ventricular unloading during angioplasty fails to improve patient outcomes

The first randomized trial to compare standard percutaneous coronary intervention (PCI), also known as coronary angioplasty, with PCI accompanied by the use of a temporary, miniaturized pump to support the heart in patients with both severe coronary heart disease and moderate to severe heart failure found no significant difference between the two approaches.

29 Mar 2026

Novel vFFR method performs similar to invasive coronary assessment

A novel, minimally invasive method of determining whether fatty deposits in a coronary artery are restricting blood flow to a patient's heart performed similarly to the standard, more-invasive procedure in a large multi-country European randomized trial presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

29 Mar 2026

Angioplasty improves symptoms in chronic total coronary occlusion patients

In what is believed to be the first randomized placebo-controlled trial of its kind, patients with a chronic total blockage of a coronary artery who received a nonsurgical procedure to reopen the artery showed statistically significant reductions in chest pain and improvements in quality of life compared with patients who received a placebo procedure.

29 Mar 2026

Intensive LDL cholesterol-lowering shows major benefits for heart disease patients

Using cholesterol-lowering medications more intensively to achieve a more aggressive target for low-density lipoprotein cholesterol (LDL-C) reduced the rate of major cardiovascular events by one-third among patients with atherosclerotic cardiovascular disease (ASCVD), according to a study presented at the American College of Cardiology's Annual Scientific Session (ACC.26).

28 Mar 2026

Medicare reforms improve medication adherence among older adults with heart disease

Medicare beneficiaries with heart disease or major cardiovascular risk factors reported less cost-related medication non-adherence-skipping or reducing doses, delaying prescription fills or foregoing medications due to cost-after new provisions went into effect limiting out-of-pocket drug costs for Medicare beneficiaries, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.26) and simultaneously published in JACC, the flagship journal of the ACC.

24 Mar 2026

AI-based ECG interpretation outperforms standard diagnosis of occlusive myocardial infarction

Artificial intelligence (AI)-based ECG interpretation outperformed standard pathways for the detection of occlusive myocardial infarction (MI), according to a study presented today at ESC Acute CardioVascular Care 2026,1 the annual congress of the Association for Acute CardioVascular Care (ACVC), a branch of the European Society of Cardiology (ESC).

23 Mar 2026

Scientists identify common symptom patterns in post-COVID-19 vaccination syndrome

A registry study across 14 Japanese clinics analyzed 179 cases of post-COVID-19 vaccination syndrome (PCVS) and identified 493 adverse events affecting multiple organ systems. Most symptoms appeared within 90 days, but some occurred much later, highlighting the need for continued vaccine safety monitoring and better clinical frameworks for persistent post-vaccination symptoms.

16 Mar 2026

ChatGPT Health fails critical emergency and suicide safety tests

ChatGPT Health, a widely used consumer artificial intelligence (AI) tool that provides health guidance directly to the public-including advice about how urgently to seek medical care-may fail to direct users appropriately to emergency care in a significant number of serious cases, according to researchers at the Icahn School of Medicine at Mount Sinai.

24 Feb 2026