Cross Linking News and Research

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Human-specific gene variant may hold key to evolution of language

The origins of human language remain mysterious. Are we the only animals truly capable of complex speech? Are Homo sapiens the only hominids who could give detailed directions to a far-off freshwater source or describe the nuanced purples and reds of a dramatic sunset?

18 Feb 2025

New diagnostic device could enable at-home early bladder cancer detection

Innovative fluorescence-based diagnostic system identifies early-stage bladder cancer with 90% accuracy, utilizing untreated urine samples for at-home testing.

23 Jan 2025

Key to LDL clearance uncovered: Structural details of apoB100-LDLR binding emerge

Researchers reveal the structural details of apoB100's interaction with LDL receptors, offering insights into LDL dimerization and potential treatments for familial hypercholesterolemia.

12 Dec 2024

Understanding cardiovascular risks in endometriosis patients

Endometriosis increases the risk of cardiovascular events.

18 Oct 2024

Auburn University researchers develop AI-driven method to target cancer proteins

Researchers at Auburn University, in collaboration with scientists from the University of Basel and ETH Zurich, have made a groundbreaking advance in the fight against cancer.

5 Sep 2024

Understanding gluten's role in autoimmunity and inflammation

The interaction between humans and their environment, mediated by nutrition, plays a crucial role in regulating inflammatory responses.

21 Aug 2024

New discovery unveils key process in DNA repair pathway

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of Molecular Biology (LMB) in Cambridge, has solved a decades-old mystery which could pave the way to better cancer treatments in the future.

31 Jul 2024

Study reveals a key step to help the heart regenerate after myocardial infarction

A new study by investigators at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham (MGB) healthcare system, reveals an important step to help the human heart regenerate after myocardial infarction (MI).

10 Jun 2024

Researchers discover how protein XPD detects and repairs DNA damage

Researchers at the University of Würzburg, led by Caroline Kisker in cooperation with Claudia Höbartner, discovered how the protein XPD detects a severe DNA damage and controls its repair.

28 May 2024

Innovative material swiftly stops kidney bleeding and facilitates wound recovery

Professor Dong-Woo Cho from the Department of Mechanical Engineering along with Jae Yun Kim, a PhD candidate, from the School of Interdisciplinary Bioscience and Bioengineering and Tugce Sen, a PhD student, from Department of Mechanical Engineering at POSTECH, teamed up with Professor Jae Yeon Lee from Daegu Haany University's Department of Companion Animal Health.

2 May 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

19 Feb 2024

Study provides insight into potential mechanisms underlying diabetes-related disc tissue damage

Type 2 diabetes alters the behavior of discs in the vertebral column, making them stiffer, and also causes the discs to change shape earlier than normal.

13 Feb 2024

DZNE neuroscientist awarded 1.5 million euros to investigate biophysical phenomena relevant to brain diseases

Dr. Dragomir Milovanovic, a neuroscientist at DZNE's Berlin site, has been awarded an European Research Council (ERC) "Starting Grant" worth 1.5 million euros to investigate biophysical phenomena relevant to brain diseases in a groundbreaking research project.

7 Nov 2023

Nanoengineered bioink improves tumor model accuracy

Scientists from the Terasaki Institute for Biomedical Innovation have developed a nanoengineered bioink with improved bonding and cross-linking capabilities for 3D bioprinting of tumor models.

3 Aug 2023

BUB1 protein and its kinase activity may regulate EGFR activation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization."

18 Jul 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

RNA regulatory mechanism could be targeted to slow AD progression mediated by stress granules

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

1 Jun 2023

New toolkit enables in-vivo cross-linking of protein complexes in live cells

As the executor of life activities, proteins exert their specific biological functions through interactions such as forming protein complexes.

9 May 2023

Revolutionizing Glycobiology: A Mass Spectrometrist's Perspective

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Professor Albert Heck and gained a mass spectrometrist's perspective on the field of glycobiology.

From Pittcon 24 Apr 2023