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Newly developed fusion protein could improve COVID-19 research

Researchers at the Paul Scherrer Institute in Switzerland have developed a high-quality recombinant virus protein that could be applied in the development of vaccines against the 2019 novel coronavirus (2019-nCoV) and in the detection of novel viruses or antibodies.

30 Sep 2020

A map of SARS-CoV-2 escape mutations enables the development of therapeutic antibody cocktails

A recent tour-de-force study by the US researchers describes a comprehensive approach to completely map mutations to the SARS-CoV-2 receptor-binding domain (RBD) that escape antibody binding – enabling, in turn, rational design of antibody therapeutics and appraisal of the antigenic consequences of viral evolution. The results are currently available in a bioRxiv preprint paper.

13 Sep 2020

Next-Generation Microscopy Image Analysis with Deep-Learning Technology

Image analysis is a critical part of many life science applications. Analyses that rely on segmentation to extract targets, such as cells and organelles, from the rest of the image are commonplace.

From Evident Corporation - Life Sciences 8 Apr 2020

Microglia play a dual role in regulating the permeability of blood-brain barrier, study shows

The blood-brain barrier is a layer of cells that covers the blood vessels in the brain and regulates the entry of molecules from the blood into the brain.

28 Feb 2020

Simple blood test could be used by GPs to aid in earlier brain tumor diagnosis

A new simple blood test for brain tumors that could be used by GPs in primary care is being developed thanks to funding of nearly £500,000 by Cancer Research UK.

24 Feb 2020

Johns Hopkins engineers create new lens-free ultra-miniaturized endoscope

Johns Hopkins engineers have created a new lens-free ultra-miniaturized endoscope, the size of a few human hairs in width, that is less bulky and can produce higher quality images.

8 Dec 2019

High-speed imaging technology reveals previously unseen details of living creatures

The Columbia team behind the revolutionary 3D SCAPE microscope announces today a new version of this high-speed imaging technology.

27 Sep 2019

Study: Single protein regulates network of genes essential for sperm development

A single protein regulates a battery of key genes inside developing sperm, according to a new study out of Case Western Reserve University School of Medicine.

31 Oct 2018

Using stem cells extracted from baby teeth to regrow dental tissues

Sometimes kids trip and fall, and their teeth take the hit. Nearly half of children suffer some injury to a tooth during childhood. When that trauma affects an immature permanent tooth, it can hinder blood supply and root development, resulting in what is essentially a "dead" tooth.

12 Sep 2018

Stem cell secretions appear to protect retinal ganglion cells in rats, study shows

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye.

27 Jan 2017

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire.

7 Nov 2016

New study unravels cause of cognitive loss in tauopathy disorders

Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells.

13 Oct 2016

NIPS researchers reveal new mechanisms by which microglia sculpt neural circuits

Microglia are cells that combat various brain diseases and injuries by swallowing foreign or disruptive objects and releasing molecules that activate repair mechanisms.

26 Aug 2016

Texas Biomed scientists receive $23 million NIH grant to develop AIDS vaccine

To support a coordinated, innovative approach to the development of an AIDS vaccine, Texas Biomedical Research Institute scientists, together with a multi-institutional coalition of experts from the United States and Europe, have received a grant for $23 million from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health.

22 Jul 2016

Scientists detect first cell from which tumour grows in skin cancers

Scientists have identified for the first time the 'cell of origin' - in other words, the first cell from which the cancer grows - in basal cell carcinoma, the most common form of skin cancer, and followed the chain of events that lead to the growth of these invasive tumours.

11 Jul 2016

Researchers reveal how bile component taurine attracts Vibrio cholera

A group of researchers from Osaka University, Hosei University, and Nagoya University have revealed the molecular mechanism that Vibrio cholerae, the etiological agent of cholera, is attracted by bile. This group has also successfully detected the ligand binding to the bacteria chemoreceptor in vivo for the first time. These results may significantly advance research on mechanism and control of V. cholerae.

26 Apr 2016

Researchers demonstrate novel method for imaging engineered nanoparticles in tissues

As a testament to Governor Andrew Cuomo’s leadership in developing an unparalleled research and development ecosystem in New York State, Sara Brenner, MD, MPH and her colleagues at SUNY Polytechnic Institute (SUNY Poly), the George Washington School of Medicine and Health Sciences, and Stony Brook University have demonstrated a novel method for the rapid visualization and identification of engineered nanoparticles in tissues.

28 Mar 2016

Neurons in hypothalamus help maintain blood glucose levels, study finds

To learn what different cells do, scientists switch them on and off and observe what the effects are. There are many methods that do this, but they all have problems: too invasive, or too slow, or not precise enough. Now, a new method to control the activity of neurons in mice, devised by scientists at Rockefeller University and Rensselaer Polytechnic Institute, avoids these downfalls by using magnetic forces to remotely control the flow of ions into specifically targeted cells.

24 Mar 2016

New imaging approach could aid earlier diagnosis of diseases

Scientists have devised a technique for visualising tissues that could aid diagnosis and treatment of diseases including cancer.

10 Mar 2016

Using centrifugal elutriation and flow cytometry to answer biological questions: an interview with Peter Lopez

Flow Cytometry, the measurement of various cellular characteristics as they flow through a measuring apparatus, has so many applications.

From Beckman Coulter Life Sciences - Centrifugation 27 Jan 2016