Genetic Information News and Research

RSS

New project investigates gut microbiome for personalized bowel disease therapies

The gut microbiome plays an important role in inflammatory bowel disease. In the research project MikrobiomProCheck, researchers are investigating how microbiome data can in future be used for diagnostics, disease monitoring and personalized therapies.

26 Jun 2026

Discovery of karyoptosis opens new therapeutic targets for Alzheimer's and frontotemporal dementia

Markers of a new mechanism for cell death, called karyoptosis, have been found in brains of patients with Alzheimer's disease and frontotemporal dementia (FTD).

25 Jun 2026

Study outlines legal challenges for fetal tissue research in Japan

Human fetal tissue research has contributed to advances in developmental biology, the study of congenital diseases, regenerative medicine, and vaccine development.

24 Jun 2026

MSU researchers develop tool to observe complex molecular choreography in real time

A lot of things need to go right on a molecular level for immune cells to launch an adaptive response to an infection.

23 Jun 2026

Mount Sinai study connects social determinants of health to disease risks

A new study from the Icahn School of Medicine at Mount Sinai shows that social determinants of health-including environmental conditions, health behaviors, access to resources, and social well-being-can play an equally important or even greater role than genetics in predicting a person's risk of developing common diseases.

22 Jun 2026

New biological age tools could reveal health risks before symptoms appear

A JCI review traces biological age measurement from functional tests and blood biomarkers to epigenetic, proteomic, imaging, wearable, and AI-based clocks. It finds that these tools can improve risk prediction beyond chronological age, but standardization, interpretability, and prospective validation are needed before routine clinical use.

18 Jun 2026

Genetic data may predict steroid side effect risk

Oral corticosteroids (OCSs) are widely used and effective in the treatment of chronic inflammatory conditions such as arthritis, asthma, and autoimmune diseases. They work by reducing inflammation, relieving pain, and calming the immune system.

14 Jun 2026

Noninvasive sequencing expands prenatal genetic screening capabilities

While non-invasive prenatal testing (NIPT) has revolutionised prenatal diagnostics by allowing the detection of a number of genetic problems in a fetus, it is currently limited and thus misses many genetic causes of abnormalities.

12 Jun 2026

Immune cell defects may drive celiac disease development

New research from the Snow Centre for Immune Health is challenging long-held assumptions about autoimmune disease, revealing that coeliac disease may be driven not just by an overactive immune system, but by subtle defects in how immune cells function.

9 Jun 2026

Ancient dental calculus reveals centuries of oral microbiome change

Researchers characterized the oral microbiomes of the Japanese population across time by analyzing the DNA preserved in dental calculus of human skeletal remains.

8 Jun 2026

Extreme trait values often have simpler genetic explanations than thought

Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.

27 May 2026

Study links fathers’ preconception stress to altered offspring development

Research from the University of Colorado Anschutz suggests that stress experienced by a father before conception may influence an offspring's growth by altering small molecular signals in sperm.

26 May 2026

Specific gene fusion patterns tied to solitary fibrous tumor outcomes

Specific genetic fusion patterns in solitary fibrous tumors may help identify which patients face a higher risk of metastasis, recurrence and more aggressive disease behavior, according to new research that could improve how physicians assess and eventually treat this rare cancer.

21 May 2026

Epigenetic research links genetics and environment to mental disorders

Mental disorders, such as obsessive-compulsive disorder (OCD) and bipolar disorder, can strongly affect daily life.

18 May 2026

New mechanism to enhance precision in cancer drug development

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from breaking when cells copy damaged genetic material, a discovery that could affect how certain cancer drugs are developed.

15 May 2026

Genetic schizophrenia risk linked to neurodevelopmental changes during early adolescence

Research has found that children with higher genetic susceptibility to schizophrenia show decreases in frontal cortical surface area during early adolescence, in contrast to the regional expansion observed in children with low genetic susceptibility.

13 May 2026

Loss of X chromosome linked to female infertility risk

Chromosomes carry genetic information for biological sex, which generally assigns women two X chromosomes and men XY chromosomes.

12 May 2026

Child abuse linked to disrupted biological development and body regulation

Children who experienced abuse or neglect displayed disrupted development and decreased ability to maintain stable function of internal bodily systems, according to a new study led by researchers in the Penn State Department of Biobehavioral Health.

8 May 2026

Reverse ecology approach reveals hidden complexity in gut microbiome

The human gut harbors a complex ecosystem of trillions of microorganisms (the microbiome), which influences digestion, the immune system and metabolism.

7 May 2026

Genetic background shapes outcomes in chromosome 16 deletion disorders

Individuals that share the same deletion of a portion of chromosome 16 are at risk of developing neurodevelopmental disorders, but some experience severe intellectual disability or developmental delay, while others may only exhibit milder psychiatric features like depression or anxiety.

5 May 2026