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Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

A combination of two drugs could improve outcomes and reduce the need for toxic chemotherapy for B-cell acute lymphoblastic leukemia (B-ALL), the commonest cancer in childhood and one that can be particularly difficult to treat in older patients, according to Cambridge scientists.

20 May 2025

Physical function before treatment predicts response to daratumumab in multiple myeloma

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti- multiple myeloma (MM) drug, according to a new study published in the European Journal of Haematology.

14 May 2025

Study shows strong COVID immunity from infection and vaccination

A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it.

9 May 2025

New QR4 model identifies hidden risk factors in cardiovascular disease

Collaborative research, led from the University of Oxford and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.

9 May 2025

Oxford study reveals how COVID-19 vaccines prevent severe illness

A landmark study by scientists at the University of Oxford, has unveiled crucial insights into the way that COVID-19 vaccines mitigate severe illness in those who have been vaccinated.

9 May 2025

Sequential cancer therapies improve survival in rare lymphomas

Study data reveal how a specific sequence of cancer therapies can improve outcomes for patients with hard-to-treat lymphomas.

2 May 2025

Clusterin identified as key marker for aging in blood stem cells

In recent years, there has been a growing trend of an aging patient population and an increasing prevalence of age-associated diseases, underscoring the need for advancing research into the biological mechanisms of aging.

30 Apr 2025

$Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma$

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Researchers from the Sant Pau Research Institute (IR Sant Pau), in collaboration with Sant Pau Hospital and the Josep Carreras Leukaemia Research Institute, have developed an innovative CAR-T cell therapy targeting the CD30 protein (HSP-CAR30), which has shown high efficacy in patients with refractory CD30+ lymphoma.

29 Apr 2025

Routine molecular monitoring doubles survival in high-risk AML subtypes

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with Acute Myeloid Leukemia (AML) by helping doctors identify if they might relapse up to three months earlier.

29 Apr 2025

Blood cancer patients should continue BTKi therapy during COVID-19 vaccination

Blood cancer patients who receive a type of anti-cancer therapy should continue to take the drug while having COVID-19 vaccinations, a new study suggests.

2 Apr 2025

Novel insights into tumor microenvironment and gastric cancer therapy

A team of Singapore scientists has made a significant discovery in understanding stomach cancer, a disease that remains one of the deadliest cancers worldwide. By using advanced mapping technologies, they created a detailed "atlas" of stomach tumors, revealing hidden patterns in how cancer cells behave, evolve and interact with their environment. These insights could lead to more precise, targeted treatments that improve survival rates and reduce side effects.

27 Mar 2025

Experts release new guidelines on JAK inhibitors for chronic inflammatory diseases

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis.

17 Mar 2025

NUS researchers enhance chemotherapy with magnetic field pulses

Researchers at the National University of Singapore (NUS) have developed a non-invasive method to improve the effectiveness of chemotherapy while reducing its harmful side effects.

6 Jan 2025

New guidelines developed to assist with the management of blood cancers in pregnancy

A new set of guidelines has been developed to assist with the diagnosis and expert management of serious blood cancers in pregnancy.

3 Jan 2025

New formula predicts oxygen delivery ability of red blood cells

SCIENTISTS have developed a way of assessing the ability of red blood cells to deliver oxygen by measuring their shape. This test could improve specialist transplant and transfusion practice as well as blood banking.

22 Dec 2024

Modified chemotherapy regimen for Hodgkin lymphoma reduces long-term side effects

A simple change to the chemotherapy regimen for people with Hodgkin lymphoma could reduce the long-term health impacts that can result from treatment, according to researchers in Cambridge.

11 Dec 2024

Antibody trials show encouraging results in patients with high-risk forms of two blood cancers

Two clinical trials testing the antibody loncastuximab tesirine (Zynlonta) showed encouraging results in patients with high-risk forms of two blood cancers – follicular lymphoma and marginal zone lymphoma.

9 Dec 2024

Concizumab shows promising results for hemophilia patients

For people with the bleeding disorder hemophilia, life can seem like one continuous state of alertness. If they accidentally cut their finger while chopping vegetables, they have to immediately administer the clotting factor protein that their body either lacks or does not produce enough of.

2 Dec 2024

New discovery could lead to better treatments for drug-resistant leukemia

Scientists from Duke-NUS Medical School and their collaborators have identified an inherited genetic variation prevalent among East Asians that contributes to drug resistance, driving the aggressive growth of cancer cells in patients with chronic myeloid leukemia.

8 Nov 2024

Advances in neutropenia research could pave the way for better treatments

Neutropenia is a condition in which there are not enough neutrophils, a type of white blood cell, in the blood.

5 Nov 2024

Haematology News and Research

Combination of two drugs shows promise in treating B-cell acute lymphoblastic leukemia

Physical function before treatment predicts response to daratumumab in multiple myeloma

Study shows strong COVID immunity from infection and vaccination

New QR4 model identifies hidden risk factors in cardiovascular disease

Oxford study reveals how COVID-19 vaccines prevent severe illness

Sequential cancer therapies improve survival in rare lymphomas

Clusterin identified as key marker for aging in blood stem cells

Innovative CAR-T cell therapy achieves remarkable results in patients with refractory CD30+ lymphoma

Routine molecular monitoring doubles survival in high-risk AML subtypes

Blood cancer patients should continue BTKi therapy during COVID-19 vaccination

Novel insights into tumor microenvironment and gastric cancer therapy

Experts release new guidelines on JAK inhibitors for chronic inflammatory diseases

NUS researchers enhance chemotherapy with magnetic field pulses

New guidelines developed to assist with the management of blood cancers in pregnancy

New formula predicts oxygen delivery ability of red blood cells

Modified chemotherapy regimen for Hodgkin lymphoma reduces long-term side effects

Antibody trials show encouraging results in patients with high-risk forms of two blood cancers

Concizumab shows promising results for hemophilia patients

New discovery could lead to better treatments for drug-resistant leukemia

Advances in neutropenia research could pave the way for better treatments

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