Hypotension News and Research

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In-hospital start of dapagliflozin shows no significant short-term benefit in heart failure patients

In-hospital initiation of dapagliflozin did not significantly reduce the short-term risk of cardiovascular death or worsening heart failure (HF) in patients admitted for HF, although positive effects were seen when combining trial data, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Ivabradine did not reduce the occurrence of myocardial injury after noncardiac surgery (MINS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Among individuals with cardiovascular disease or high cardiovascular risk and uncontrolled hypertension on multiple anti-hypertensive agents, a single subcutaneous dose of zilebesiran 300 mg led to a 5-mmHg reduction in systolic blood pressure at Month 3 compared with placebo, a difference that did not reach statistical significance.

1 Sep 2025

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

Aggressive blood pressure management offers greater health benefits

Research led by investigators at Mass General Brigham suggests that the health benefits of more aggressive blood pressure control outweigh concerns about overtreating people with high blood pressure readings. Results of the simulation study are published in Annals of Internal Medicine.

19 Aug 2025

Addressing avoidable hospitalizations in terminally ill nursing home residents

Hospitalizations and emergency department (ED) visits can be distressing and costly for nursing home residents – especially those who are severely impaired or terminally ill. Despite their vulnerability, these individuals are frequently transferred to hospitals, even though up to 40% of such transfers over the past 25 years are considered potentially avoidable by health care professionals.

25 Jul 2025

New guidance helps GPs manage patients using weight loss drugs

Academics at King's College London and the University of East Anglia have released guidance for GPs on how to manage patients who may be privately accessing weight loss drugs.

25 Jun 2025

ADC189 shows promise as a single-dose treatment for influenza

Influenza continues to pose a significant global health burden, with seasonal outbreaks causing substantial morbidity and mortality.

24 Jun 2025

PDE3 inhibitors show promise in promoting bone growth

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone.

17 Jun 2025

Two blood pressure management strategies yield similar cognitive outcomes after non-cardiac surgery

A large international study has found that two different approaches to managing blood pressure in older adults undergoing non-cardiac surgery, one avoiding low blood pressure (hypotension) and the other high blood pressure (hypertension), lead to similar outcomes in terms of in-hospital delirium and cognitive changes one year after surgery.

4 Jun 2025

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Researchers have found that prescribing guideline-directed medical treatment (GDMT), regardless of the number of medications, can improve survival rates in patients 90 years of age and older following their first heart attack, with the greatest benefit observed in patients who received all four recommended post-acute myocardial infarction (AMI) therapies.

22 May 2025

Study: One in four early cardiogenic shock patients experience worse outcomes

In one of the largest studies of early cardiogenic shock (CS) patients, where blood flow is still functioning to vital organs, researchers demonstrated that 26% experienced worse outcomes, including care escalation, CS deterioration, or in-hospital mortality.

2 May 2025

Researchers create an atlas of health associations for GLP-1 receptor agonists

Insights from a study on GLP-1 receptor agonists reveal benefits for cardiometabolic health, with notable risks for gastrointestinal and musculoskeletal issues.

20 Jan 2025

New advisory offers evidence-based strategies to prevent postoperative delirium in older adults

Delirium and cognitive decline are common complications of anesthesia and surgery in older adults.

10 Dec 2024

Adults with egg white allergy face significant quality of life challenges

Study reveals significant impairments in the quality of life for adults with hen's egg white allergy, highlighting the need for accurate food labeling and further research into effective treatments.

27 Nov 2024

Wearable ultrasound sensor revolutionizes continuous blood pressure monitoring

Researchers validated a novel wearable ultrasound blood pressure (BP) sensor, confirming its accuracy and safety across diverse clinical settings.

24 Nov 2024

Intensive blood pressure treatment reduces cardiovascular risk in people with Type 2 diabetes

An intensive treatment approach to lowering high systolic blood pressure in people with Type 2 diabetes led to a reduced risk of heart attack, stroke, heart failure and death due to cardiovascular disease when compared to a standard treatment approach, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2024.

18 Nov 2024

Hypotension News and Research

In-hospital start of dapagliflozin shows no significant short-term benefit in heart failure patients

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Phase II trial finds zilebesiran lowers systolic blood pressure in patients with uncontrolled hypertension

Rethinking chronic disease management in older adults

Aggressive blood pressure management offers greater health benefits

Addressing avoidable hospitalizations in terminally ill nursing home residents

New guidance helps GPs manage patients using weight loss drugs

ADC189 shows promise as a single-dose treatment for influenza

PDE3 inhibitors show promise in promoting bone growth

Two blood pressure management strategies yield similar cognitive outcomes after non-cardiac surgery

Guideline-directed medical therapy boosts survival in the oldest heart attack patients

Study: One in four early cardiogenic shock patients experience worse outcomes

Researchers create an atlas of health associations for GLP-1 receptor agonists

New advisory offers evidence-based strategies to prevent postoperative delirium in older adults

Adults with egg white allergy face significant quality of life challenges

Wearable ultrasound sensor revolutionizes continuous blood pressure monitoring

Intensive blood pressure treatment reduces cardiovascular risk in people with Type 2 diabetes

Study suggests beta-blockers may elevate depression symptoms in post-MI patients

Advances in neutropenia research could pave the way for better treatments

Study warns of increasing Rocky Mountain spotted fever cases among children in California

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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