Immune System News and Research

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Cell proliferation gene plays a distinct role in cells that no longer proliferate

In a tale of identities as divergent as "The Prince and the Pauper," a well-known cancer-causing gene also influences cells in a zombie-like state meant to prevent cancer.

28 Aug 2026

Machine learning maps changing immune response over time in sepsis

Researchers have mapped how the immune response in people with sepsis changes over time.

28 Aug 2026

New research questions decades-old assumptions about brain cancer treatment

Australian researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumors, while reducing damage to healthy tissue.

28 Aug 2026

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Leading African biopharmaceutical company Minapharm Group, headquartered in Egypt with subsidiaries in Berlin, will receive up to US$16.5 million from the Coalition for Epidemic Preparedness Innovations (CEPI) to advance the development of a Bundibugyo ebolavirus vaccine candidate, strengthening efforts to develop vaccines to combat the fastest-growing and second-largest Ebola outbreak on record affecting the Democratic Republic of the Congo (DRC).

28 Aug 2026

Newly identified cells protect lung tumors from immune attacks

Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system.

27 Aug 2026

Researchers tested dozens of clues for long COVID. One finding stood out

A nationwide study of 218 people in the Faroe Islands examined clinical, neurological, and blood-based markers associated with persistent symptoms around six months after SARS-CoV-2 infection. Despite extensive testing, researchers found no convincing biomarker for long COVID, while a statistical association with lower INR remained within the normal clinical range and requires replication.

27 Aug 2026

Mayo Clinic joins multi-million dollar gene-editing project for children

Mayo Clinic is a clinical collaborator on an award of up to $27.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to help develop affordable, scalable gene-editing therapies for children with rare inherited immune disorders.

27 Aug 2026

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

Immunotherapies such as CAR T-cell therapy are used primarily to treat cancer. In the future, these patient-specific therapies, manufactured from patients' own immune cells, could also help cure autoimmune diseases.

27 Aug 2026

UMass Amherst researcher wins $2.5 million to expand nanoparticle cancer vaccine study

Having established the effectiveness of her nanoparticle drug-delivery system for cancer immunotherapy, University of Massachusetts Amherst researcher Prabhani Atukorale, has been awarded $2.5 million from the National Institutes of Health to broaden the scope of her vaccine research to include treating those with active cancer.

27 Aug 2026

New funding backs pioneering research to make brain cancer treatment more effective

Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumors, while reducing damage to healthy tissue.

27 Aug 2026

Research improves understanding of biological mechanisms behind cluster headaches

Inflammation, altered gene regulation, and exposure to substances in tobacco smoke may all contribute to the development of cluster headache.

26 Aug 2026

Experimental vaccine protects against Zika virus through T cells alone

Zika virus has been spreading for decades, but it first grabbed worldwide headlines in 2016. That February, with an outbreak sweeping the Americas, the World Health Organization (WHO) declared the surge in Zika-linked birth defects a "public health emergency of international concern"-a designation which lasted until that November.

26 Aug 2026

Protecting the thymus may improve lung cancer treatment outcomes

Building on recent discoveries about the adult thymus, Mass General Brigham investigators used artificial intelligence to show that incidental radiation exposure to the thymus may influence outcomes in patients with lung cancer.

25 Aug 2026

Study links thymus radiation to worse lung cancer outcomes

Until recently, the thymus was thought to be of little use beyond puberty, but new research has shown that radiation to the organ is associated with worse outcomes in patients being treated for non-small cell lung cancer (NSCLC).

25 Aug 2026

Researchers traced lifelong obesity resistance in mice back to an early microbial encounter

Natural wild-derived microbiota protected mice against diet-induced obesity across sexes, genetic backgrounds, and age by increasing energy expenditure and promoting a thermogenic program in brown adipose tissue. The effect depended on the immune system’s initial encounter with the microbiota and required CCR2-associated myeloid activity, revealing a long-lasting microbiota-immune-brown fat pathway.

25 Aug 2026

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

UMass Chan Medical School scientist Beth McCormick, PhD, and her team collaborated with researchers at the University of Bath to discover how neutrophils, the body's most abundant type of white blood cells, travel to infection sites without damaging healthy tissue.

25 Aug 2026

Gene removal makes engineered immune cells more effective against osteosarcoma

Scientists at St. Jude Children's Research Hospital have discovered that removing the gene for Regnase-1 from engineered immune cells makes them more effective at treating relapsed osteosarcoma.

25 Aug 2026

Martha's Vineyard Hospital launches study to better understand alpha-gal syndrome

Martha's Vineyard Hospital, a member of Mass General Brigham, has begun recruiting participants for a research study designed to better understand alpha-gal syndrome (AGS), a potentially serious allergic condition associated with lone star tick exposure.

25 Aug 2026

Study finds distinct patterns of innate immune activity in mental disorders

The immune system may also play a role in mental disorders. Scientists are investigating these links with brain function in greater detail, and new findings show that immune changes may differ by disorder type.

25 Aug 2026

Yeast-based nanoparticle vaccine could make annual flu shots obsolete

The world mostly relies on an 80-year-old method for producing flu vaccines from chicken eggs - a slow, costly process that struggles to quickly adapt to new, mutant strains.

24 Aug 2026

Immune System News and Research

Cell proliferation gene plays a distinct role in cells that no longer proliferate

Machine learning maps changing immune response over time in sepsis

New research questions decades-old assumptions about brain cancer treatment

African Bundibugyo ebolavirus vaccine candidate to be advanced to clinical trials

Newly identified cells protect lung tumors from immune attacks

Researchers tested dozens of clues for long COVID. One finding stood out

Mayo Clinic joins multi-million dollar gene-editing project for children

CAR T-cell therapy successfully reverses severe rheumatoid arthritis

UMass Amherst researcher wins $2.5 million to expand nanoparticle cancer vaccine study

New funding backs pioneering research to make brain cancer treatment more effective

Research improves understanding of biological mechanisms behind cluster headaches

Experimental vaccine protects against Zika virus through T cells alone

Protecting the thymus may improve lung cancer treatment outcomes

Study links thymus radiation to worse lung cancer outcomes

Researchers traced lifelong obesity resistance in mice back to an early microbial encounter

Scientists discover how neutrophils travel to infection sites without damaging healthy tissue

Gene removal makes engineered immune cells more effective against osteosarcoma

Martha's Vineyard Hospital launches study to better understand alpha-gal syndrome

Study finds distinct patterns of innate immune activity in mental disorders

Yeast-based nanoparticle vaccine could make annual flu shots obsolete

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