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KRISS develops ultra-sensitive platform to detect Alzheimer’s biomarkers in body fluids

The Korea Research Institute of Standards and Science (KRISS, President Lee Ho Seong) has developed a diagnostic platform that amplifies the unique optical signals of molecules by more than a hundred million times, enabling the precise detection and quantification of trace amounts of Alzheimer's disease biomarkers in body fluids.

1 Sep 2025

Gecko-inspired nanoparticles deliver targeted chemotherapy to tumors

As far back as the 4th Century B.C., Aristotle marveled at the nimble gecko's ability to "run up and down a tree in any way, even with the head downwards."

21 Jul 2025

NUS researchers develop breakthrough gene delivery technology for immune cells

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells.

26 May 2025

Peptide nanostructures block amyloid buildup and boost neuron survival in lab tests

Researchers developed trehalose-functionalized peptide amphiphiles (TPAs) that self-assemble into supramolecular nanostructures and demonstrated these TPAs can inhibit amyloid beta aggregation. In vitro, TPAs significantly improved survival of human neurons exposed to amyloid-induced neurotoxicity, suggesting therapeutic potential for neurodegenerative diseases.

15 May 2025

New era of medicine emerges through structural control of nanotherapeutics

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

25 Apr 2025

Researchers develop magnetic nanoparticles for precise cancer treatment

Traditionally, radiation, chemotherapy, and surgery have been the most common ways to remove and destroy malignant cells.

6 Mar 2025

Takumi-shaped DNA hydrogels show promise for targeted therapies

Hydrogels are polymeric materials with three-dimensional network structures containing large amounts of water. They serve as sustained-release drug delivery systems as they can encapsulate various bioactive substances, including drugs, antigens, and even cells.

13 Feb 2025

University of Oulu advances biosensor technology for disease detection

The University of Oulu is at the forefront of developing cutting-edge biosensor technology that could revolutionize the early diagnosis and treatment of diseases.

10 Feb 2025

The science of silk fibroin and chitosan: Techniques for biomaterials analysis

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 21 Jan 2025

Graphene breakthrough offers hope against antibiotic-resistant infections

With strong bactericidal properties, graphene has the potential to become a game changer in the fight against antibiotic-resistant bacteria.

24 Sep 2024

Breakthrough technology detects cancer mutant genes with unprecedented sensitivity

Dr. Min-young Lee and Dr. Sung-gyu Park of the Advanced Bio and Healthcare Materials Research Division at KIMS have developed a technology that can detect cancer mutant genes in blood with the world's highest sensitivity of 0.000000001% based on plasmonic nanomaterials for optical signal amplification.

6 Sep 2024

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

New strategy for mRNA nanocarriers using triphenyl phosphonium

Among the vastly different ways of tackling a disease, controlling the genetic expression of cells is undoubtedly one of the most powerful. Over the past few decades, scientists have come up with dozens of innovative strategies that involve using messenger RNA (mRNA) to 'force' cells to build specific proteins. These mRNA-based therapies have recently gained prominence as vaccines against infectious diseases like COVID-19. Additionally, they hold significant potential for treating cancer and genetic disorders.

23 Jul 2024

New microscopy technique unveils dynamic structure of amyloid-beta

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's.

19 Jul 2024

New 3D model sheds light on amyloid-beta's impact

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have unveiled a pioneering study shedding light on the intricate mechanisms underlying Alzheimer's disease (AD). The study, titled "Effects of amyloid-β-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype," represents a significant leap forward in understanding the interplay between amyloid-like structures and neuronal cells.

13 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Rice and MD Anderson collaborative harnesses engineering expertise for cancer solutions

Led by Rice's Gang Bao and MD Anderson's Dr. Jeffrey Molldrem, the initiative aims to foster collaboration between the two institutions on fundamental and translational cancer research, to develop new technologies for cancer detection and therapy and to secure external funding in support of further research and training.

27 Jun 2024