Nucleotides News and Research

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A yeast-derived genetic tool offers hope for mitochondrial disorders and cancer

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division.

17 Feb 2026

Study explores how reversible RNA editing could transform future cardiovascular medicine

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

15 Feb 2026

Metabolic reprogramming drives prostate cancer progression and treatment resistance

Prostate cancer (PCa) is one of the most common malignant tumors among men worldwide. Following androgen deprivation therapy (ADT), the disease often progresses to castration-resistant prostate cancer (CRPC).

24 Jan 2026

Study finds increased rates of DNA mutations in mice pups conceived with IVF

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive technologies suggests.

17 Nov 2025

Ribosomal RNA found to share unique motifs with nervous system genes

Ribosomal RNA (rRNA) is a type of molecule and a key building block of the ribosome, the cell's protein-making machinery. rRNA accounts for much of the RNA in a cell, and it's crucial for life.

14 Oct 2025

Common food additives may trigger childhood asthma

Researchers utilize metabolomics to investigate the mechanisms underlying the association between food additives and childhood asthma.

6 Oct 2025

Study uncovers new associations between gut microbiome and aging process

A new research paper was published in Volume 17, Issue 8 of Aging-US on August 1, 2025, titled "Causal relationships between gut microbiome and hundreds of age-related traits: evidence of a replicable effect on ApoM protein levels."

10 Sep 2025

Mitochondria fight infection by starving parasites of essential nutrients

You've heard that mitochondria are the "powerhouse of the cell." Now get ready for "mitochondria are the infantry of the cell!"

26 Aug 2025

Researchers solve longstanding mystery of protein release in cells

It's known as biology's central dogma: All living organisms' genetic information is stored in DNA, which is transcribed into RNA, which is translated into proteins that perform nearly all essential tasks in a cell.

5 Aug 2025

Study shows how ribose may have become the sugar of choice for RNA development

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes.

22 Jul 2025

Sperm RNA profiles could identify the best embryos for IVF

Findings on sperm RNA suggest new biomarkers for IVF success, potentially improving embryo selection and reducing cycles needed for desired fertility outcomes.

21 Jul 2025

NIST releases first publicly consented pancreatic cancer genome data

In an effort to foster progress in cancer research, the National Institute of Standards and Technology (NIST) is releasing detailed and comprehensive data about the entire genetic content of a pancreatic cancer cell.

16 Jul 2025

New discovery uncovers hidden drivers of DNA transcription errors

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

11 Jul 2025

Smallest known protein-based enzyme HARP reveals dual role in tRNA processing

To build proteins, cells rely on a molecule called transfer RNA, or tRNA. tRNAs act like protein-building couriers, where they read the genetic instructions from messenger RNA, mRNA, and deliver the right amino acids to ribosomes, the cell's protein-making factories.

7 Jul 2025

Improving RNA drug delivery through intracellular traffic control

A recent study involving researchers from the University of Basel reveals that slowing down the intracellular transport of RNA-based drugs can significantly enhance their effectiveness.

1 Jul 2025

LMU researchers uncover mechanism for metabolism without cell membranes

LMU researchers have demonstrated a possible mechanism for metabolic processes without cell membranes in water-filled pores.

27 Jun 2025

Yale researchers triple precision and efficiency in genome editing

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field.

18 Jun 2025

Scientists reveal how RNA could have replicated on early earth

Chemists at UCL and the MRC Laboratory of Molecular Biology have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth – a key process in the origin of life.

28 May 2025

Can folic acid prevent or promote breast cancer? It depends on dose and DNA

Folic acid plays a dual role in breast cancer depending on dose and context. While moderate intake may reduce risk, high levels or genetic variants disrupting metabolism may promote tumor progression via altered DNA methylation.

30 Apr 2025

lncRNAs shape the tumor microenvironment and drive cancer development

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting to influence tumorigenesis, progression, and metastasis.

24 Apr 2025