Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blood biomarker test improves detection of hidden brain injuries

Clinician-scientists hope to expand the use of blood-based biomarker tests for traumatic brain injury (TBI) to improve identification and escalation of care for patients whose diagnosis otherwise might be missed.

23 Oct 2026

What can 6,000 brain scans tell us about Alzheimer's?

KARI's multimodal imaging dataset reveals critical insights into Alzheimer's disease, linking amyloid, tau, and brain structure to cognitive performance.

23 Oct 2026

Starting survivorship care earlier improves head and neck cancer survival

Beginning survivorship care for head and neck cancer patients earlier is linked to better survival and lower recurrence, according to a new University of Pittsburgh study published today in JAMA Otolaryngology–Head & Neck Surgery.

22 Oct 2026

Maladaptive brain-state locking framework redefines chronic brain disorders

Neurodevelopmental, psychiatric, and neurodegenerative disorders are traditionally studied separately yet show overlapping disturbances in neural regulation and resilience.

21 Oct 2026

Liquid biopsy reliably detects early-stage lung cancer recurrence risk

Despite advances in early-stage lung cancer treatment, a significant number of patients experience disease recurrence after surgery or initial therapy.

20 Oct 2026

New study identifies protein factor linked to chronic liver disease

The mechanisms that cause the world's most common chronic liver disease — Metabolic dysfunction-associated steatotic liver disease (MASLD) — to develop and progress are not still fully understood.

20 Oct 2026

A protective brain enzyme may counteract aging-associated cognitive decline

Cinzia Vicidomini, PhD, and Amar Sahay, PhD, of the Mass General Brigham Department of Psychiatry, the Harvard Stem Cell Institute and the Broad Institute of Harvard and MIT, are the lead and senior authors of a paper published in Nature Neuroscience, "An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilience."

15 Oct 2026

Recurrent brain tumors undergo unique genetic changes after treatment

When patients are diagnosed with certain brain tumors, one of the biggest unanswered questions is what happens when the cancer returns.

14 Oct 2026

$5.8 million study explores gut-brain inflammation in people with HIV

Oregon Health & Science University researchers have secured a $5.8 million, five-year federal award to investigate whether damage to the gastrointestinal tract contributes to neuroinflammation in people living with HIV - raising the potential for new treatments to preserve brain function in people with HIV and older adults.

13 Oct 2026

Pancreatic cancer cells continuously reshape DNA to evade treatment

A new analysis of nearly half a million cells from dozens of pancreatic tumors, led by researchers at UC San Diego Moores Cancer Center and New York University (NYU), reveals how pancreatic cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment.

13 Oct 2026

New AI tool distinguishes Ewing sarcoma with high accuracy

A team from the Universitat Politècnica de València (UPV) and the University of Valencia (UV) has developed and validated an artificial intelligence (AI) system capable of distinguishing Ewing sarcoma from other morphologically similar tumours with high accuracy.

13 Oct 2026

Single-cell analysis reveals how pancreatic cancer evades treatment

An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer.

13 Oct 2026

Buck Institute and Georgetown lead effort mapping harmful protein changes before disease begins

A research "super team" co-led by theBuck Institute for Research on Aging and Georgetown University has received an award of up to $51.7 million from the Advanced Research Projects Agency for Health (ARPA-H) to predict how disease-causing proteins misfold before irreversible damage occurs and use those predictions to develop novel diagnostics and treatments.

12 Oct 2026

A study links a blood protein to memory and brain changes in Down syndrome

Researchers studying 88 adults with Down syndrome and 43 controls estimated that serum β-synuclein increased approximately two decades before expected Alzheimer’s symptoms, preceding changes in other blood biomarkers. Higher levels correlated with poorer memory and brain changes, but the cross-sectional study could not distinguish whether the earliest increase reflected Alzheimer’s-related synaptic dysfunction, trisomy 21-related neurobiology, or both.

11 Oct 2026

New immune aging map helps decode future chronic disease risks

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health.

9 Oct 2026

Study uncovers a protective role for microglia in Parkinson's disease

Researchers at the University of Oxford have uncovered a previously unrecognized protective role for microglia, the brain's resident immune cells, in Parkinson's disease.

7 Oct 2026

Study finds β-synuclein as early blood-based biomarker of Alzheimer's in Down syndrome patients

Decades before the first symptoms of Alzheimer's disease appear, some changes associated with the disease may begin to leave a trace in the blood.

7 Oct 2026

Psychopathic traits linked to distinct patterns in everyday language

Popular culture often depicts people with psychopathy as cold, emotionless and hollow, but a recent University of Mississippi study found that the language associated with psychopathic traits is more complicated than often described.

6 Oct 2026

Global scientific collaboration brings hope to lobular breast cancer patients

Every October, Breast Cancer Awareness Month brings people around the world together under the pink ribbon to raise awareness, encourage early detection, support patients and fund research.

6 Oct 2026

Skin biopsy offers less invasive diagnosis for mitochondrial disease

Researchers at Children's Hospital Colorado (Children's Colorado) and the University of Colorado Anschutz School of Medicine have published one of the largest studies to date evaluating advanced laboratory testing for mitochondrial disease, providing new evidence that a small skin biopsy can often help diagnose these rare and complex conditions without the need for more invasive procedures.

6 Oct 2026