Perioperative News and Research

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Children face lasting challenges after caustic esophageal injury surgery

Caustic ingestion remains a serious pediatric health problem, especially in domestic settings where corrosive substances may be improperly stored.

7 May 2026

Real-world study examines cangrelor dosing for antiplatelet bridging after PCI

A multi-center retrospective cohort study examined how cangrelor has been used in real-world clinical practice around the time of surgery following percutaneous coronary intervention (PCI) and described differences in outcomes seen with different dosing approaches.

24 Apr 2026

OYE Therapeutics doses first subject in bridging study of intravenous caffeine formulation

OYE Therapeutics Inc., a clinical-stage biotechnology company developing therapies for perioperative and emergency medicine, announced that the first subject has been dosed in its scientific bridging study evaluating OYE-101.

7 Apr 2026

GLP-1 medications show mixed effects on body contouring outcomes

For patients undergoing body contouring surgery to remove excess abdominal skin after massive weight loss, use of GLP-1 weight-loss medications may have mixed effects on complication risks, suggests a study in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

26 Mar 2026

Continuous wearable monitoring improves postoperative oxygen levels and patient safety

Patients continuously monitored after surgery experienced significantly less time with dangerously low oxygen levels compared to those monitored using routine spot checks, a new study from Wake Forest University School of Medicine found.

24 Mar 2026

High-risk patients account for majority of postoperative deaths and readmissions

A major new study, led by Queen Mary University of London and funded by the National Institute for Health and Care Research (NIHR) has been published in The Lancet Public Health.

25 Feb 2026

Rural cancer patients benefit from local surgical care

Adults living in rural communities often travel long distances when seeking treatment for cancer, but distant travel may not always be necessary to receive high-quality surgical care, according to a new analysis published in the Journal of the American College of Surgeons (JACS).

11 Feb 2026

Mindfulness enables unsedated endoscopy with higher patient satisfaction

A new study has shown that mindfulness helps patients to relax during an endoscopy, allowing doctors to carry out detailed examinations without the need for sedation or general anesthesia.

10 Feb 2026

Why cardiologist evaluation matters after non-cardiac surgery

Interdisciplinary collaboration with cardiologists in non-cardiac surgery enhances patient outcomes, reducing cardiac event risks and improving survival rates.

3 Feb 2026

Cardiology consults post-surgery may reduce heart risks and mortality rates

An estimated 4.2 million people die within 30 days of surgery worldwide each year. A new study, published in the European Heart Journal today (Thursday), suggests that deaths and serious heart disease might be prevented if some patients see a specialist heart doctor as part of their post-surgery care.

30 Jan 2026

Oral cancer pain and opioid tolerance share a common EGFR mechanism

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective, according to new research published in Science Signaling.

29 Jan 2026

AI predicts health outcomes for premature newborns from blood samples

An artificial intelligence-based tool can predict the medical trajectories of individual premature newborns from blood samples collected soon after they are born, a Stanford Medicine-led study has shown.

21 Jan 2026

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

14 Jan 2026

More surgical patients on opioid use disorder treatment demand updated pain care

As more Americans receive treatment for opioid use disorder, that progress is increasingly showing up in the operating room, creating an urgent need to modernize how pain is managed during and after major surgery, according to a study in the February 2026 issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

13 Jan 2026

Understanding sevoflurane-induced neurogenesis inhibition and cognitive dysfunction in children

Every year, millions of infants and children undergo surgery under general anesthesia in the world. Sevoflurane is a commonly used pediatric anesthetic. Its exposure during brain development has been shown to inhibit neurogenesis and cause cognitive dysfunction in animal models.

5 Jan 2026

AI model may help make liposuction safer

A newly developed artificial intelligence (AI) model is highly accurate in predicting blood loss in patients undergoing high-volume liposuction, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

26 Dec 2025

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery.

12 Dec 2025