Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Real-world study shows Oregon psilocybin services relieve mental health symptoms

People participating in an Oregon Health & Science University-led study of state-regulated psilocybin services reported relief from symptoms of anxiety, depression and post-traumatic stress disorder - with almost two-thirds declaring the experience to be among the most meaningful of their life.

19 Aug 2026

Shifting expectations of unpredictability could help treat schizophrenia delusions

New research has found that improvements to the severity of delusions in patients with schizophrenia-spectrum disorder recovering from an acute psychotic episode were significantly associated with reductions in volatility priors—someone's expectations about the unpredictability of their environment.

18 Aug 2026

Better sleep may boost academic and social success in adolescents

A new UC Davis Health study published in Psychological Medicine suggests that when it comes to helping adolescents succeed in school and maintain healthy friendships, sleep may matter more than screen time, exercise or diet.

4 Aug 2026

Study connects late-life psychosis to abnormal tau protein buildup

Hallucinations and delusions that appear for the first time in midlife or later are often treated as psychiatric symptoms whose biological cause is unclear.

4 Aug 2026

Motor abnormalities may predict multiple mental health disorders

Motor issues-such as coordination problems, motor slowing, or sudden, uncontrolled movements-have been recognized as signs of psychological disorders since the 1800s. How they map to mental health conditions, however, remains unknown.

22 Jul 2026

AI-powered digital twins help train future mental health clinicians

Researchers from the University of Pennsylvania, New York University and Penn's Linguistic Data Consortium have received a two-year, $4 million grant from the Wellcome Trust to develop a scalable, AI-powered platform for training mental health clinicians.

9 Jul 2026

Trial shows potential benefit of ketogenic diet for treating psychotic disorders

Published today in Schizophrenia Bulletin, a first-of-its-kind randomized controlled trial (RCT) from researchers at the University of California, San Francisco (UCSF), and funded in part by the National Institute of Mental Health (NIMH), adds to growing literature on the potential benefit of a ketogenic diet for treating psychotic disorders.

8 Jul 2026

Reduced sunshine linked to higher demand for mental health care

The study highlights the relationship between weather and mental health care use, suggesting routine weather patterns could forecast service demand effectively.

3 Jul 2026

Scientists urge caution over psychedelics as ADHD treatment

In recent years, there has been growing interest among adults with ADHD in the practice of microdosing classic psychedelics such as psilocybin and LSD.

1 Jul 2026

Global review reveals persistent discrimination against people with psychosis

People with psychosis continue to face abuse, discrimination and early death, despite global reform efforts to protect their human rights, according to La Trobe University researchers.

30 Jun 2026

Trauma-focused therapy safely improves PTSD symptoms in psychosis patients

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London and published in The Lancet Psychiatry has found that people with psychosis experiencing Post Traumatic Stress Disorder (PTSD) can benefit from a Trauma-Focused therapy integrated with Cognitive Behavior Therapy for psychosis (CBTp).

17 Jun 2026

Study links commercial cannabis markets to increased addiction

Removing criminal penalties for possessing cannabis for personal use, or introducing tightly controlled legalisation of cannabis, does not appear to increase levels of cannabis use.

17 Jun 2026

Adverse life experiences alter brain structure linked to schizophrenia

Carnegie Mellon University and University of California, San Francisco researchers found that childhood trauma, poverty, social isolation and other adverse life experiences are associated with brain changes linked to schizophrenia-spectrum disorders - findings that could help researchers identify people at risk earlier and develop interventions before severe symptoms emerge.

17 Jun 2026

FutureNeuro launches proteomics study to personalize psychosis treatment

FutureNeuro, the Research Ireland Centre for Translational Brain Science hosted by RCSI University of Medicine and Health Sciences, has launched a new proteomics study aimed at identifying biological markers that could support more personalized treatment for people experiencing first‑episode psychosis.

16 Jun 2026

Large study uncovers brain network differences in bipolar disorder

New research from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has discovered subtle but widespread differences in the brain's communication networks in people with bipolar disorder, offering new insight into how illness severity and treatment may relate to brain wiring.

9 Jun 2026

Cannabis and tobacco co-use lowers cognitive performance in at-risk youth

New research shows that among people at clinical high risk for psychosis, cannabis and tobacco co-use was associated with lower cognitive performance compared to healthy controls.

2 Jun 2026

Most college students with psychosis lack recommended combination treatment

Although the majority of students sought and received therapy or counseling in the past 12 months, less than 40 percent received the recommended combination of therapy/counseling and antipsychotic medication, suggesting potential barriers to accessing this medication.

20 May 2026

Blood protein biomarkers predict psychosis risk in Asian youth

A new study by researchers from NHG Health's Institute of Mental Health (IMH) and Nanyang Technological University, Singapore's (NTU Singapore) Lee Kong Chian School of Medicine (LKCMedicine) has identified blood-based proteomic biomarkers that may help predict who among the at-risk group is at increased risk of developing psychosis.

20 May 2026

Study identifies genetic pathways linking cannabis use and psychosis

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has highlighted the distinct and shared molecular pathways linking cannabis use disorder (CUD) and psychosis, offering the potential for identifying those at risk, as well as targeted interventions for cannabis related psychosis.

13 May 2026

Cannabis and tobacco co-use may increase psychosis risk

A new multisite study published in Nature Mental Health found that using cannabis and tobacco together increases the risk of developing psychotic disorders like schizophrenia among those considered high risk.

12 May 2026