Septic Shock News and Research

RSS

Statins linked to lower death rates in critically ill sepsis patients

Sepsis is when the immune system overshoots its inflammatory reaction to an infection, so strongly that the vital organs begin to shut down.

6 Jun 2025

IL-6 emerges as early sepsis indicator in high risk groups

A pioneering study presented today at ESCMID Global 2025 has uncovered the potential of interleukin-6 (IL-6) as a powerful diagnostic biomarker for the early detection of sepsis in high-risk patient groups, including neonates, children and pregnant women.

11 Apr 2025

New insights into bacterial defense mechanisms could help combat antibiotic resistance

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades.

4 Apr 2025

New approach shows promise for uncovering potential sepsis treatments

The immune system typically can ramp up the body's defenses to clear out an invading threat without issue.

11 Mar 2025

Study uncovers two inhibitors to halt metaplastic breast cancer progression

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

3 Feb 2025

NIH awards $3.96 million to develop combination therapies for superbugs

Gram-negative bacteria pose a serious threat to global health because they can resist multiple antibiotics, making infections difficult to treat, according to the National Institutes of Health.

15 Nov 2024

Research reveals AI's potential to transform hospital reporting processes

A pilot study led by researchers at University of California San Diego School of Medicine found that advanced artificial intelligence (AI) could potentially lead to easier, faster and more efficient hospital quality reporting while retaining high accuracy, which could lead to enhanced health care delivery.

21 Oct 2024

MicrosensDx collaborates with Imperial researchers to develop groundbreaking sepsis test

MicrosensDx is excited to announce that it is working with The Mayr Group at Imperial College London to develop a novel biomarker test for the early recognition of sepsis.

From MicrosensDx 17 Sep 2024

Major surgery complications unaffected by use of renin-angiotensin system inhibitors

There was no difference in major post-operative complications in patients who continued vs. stopped renin-angiotensin system inhibitors (RASIs) before non-cardiac surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

Rare genetic mutation tied to increased risk of tuberculosis

Tuberculosis is a confounding scourge. It's the leading cause of death from infectious disease in the world, and yet it's estimated that those deaths represent perhaps 5% of infections with Mycobacterium tuberculosis (Mtb).

30 Aug 2024

SARS-CoV-2 protein linked to onset of multisystem inflammatory syndrome in children

St. Jude Children's Research Hospital scientists have identified a link between a SARS-CoV-2 protein and the onset of multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

Wearable, non-invasive device can measure activity in human cervical nerves in clinical settings

A research team led by UC San Diego has, for the first time, shown that a wearable, non-invasive device can measure activity in human cervical nerves in clinical settings.

29 Jul 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Kefir shows promise in improving gut health of ICU patients, study finds

The safety, feasibility, and impact of kefir administration on the gut microbiome of critically ill adults.

28 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Updated pediatric sepsis definition could save countless children's lives

An international research team led by Tell Bennett, MD, MS, professor of biomedical informatics and pediatric critical care at the University of Colorado School of Medicine, released new diagnostic criteria for sepsis in children this week, marking the first update to the pediatric sepsis definition in nearly two decades.

22 Jan 2024