Two photon Microscopy News and Research

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Two-photon microscopy (also known as two-photon fluorescence light microscopy) was invented in 1990 as a new method of imaging live cells and tissues in three-dimensions. Conventional fluorescence microscopy illuminates a specimen through the processes of excitation and emissions.

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Stem cells in the brain divide over months to create new nerve cells

For the first time, scientists at the University of Zurich have been able to observe stem cells in the adult mouse brain that divide over the course of several months to create new nerve cells. The study shows that brain stem cells are active over a long period, and thus provides new insights for stem cell research.

21 Dec 2020

Penn State engineers find link between nitric oxide expressing neurons and arterial dilation

Neurons control blood flow in tiny vessels in the brain, but researchers know little about this relationship.

16 Dec 2020

UNC scientists find brain cells that help drive arousal responses to strong emotions

Strong emotions such as fear and anxiety tend to be accompanied and reinforced by measurable bodily changes including increased blood pressure, heart rate and respiration, and dilation of the eyes' pupils. These so-called "physiological arousal responses" are often abnormally high or low in psychiatric illnesses such as anxiety disorders and depression.

23 Nov 2020

Researchers develop advanced imaging technique to visualize effects of valencies on B cell responses

Designing a vaccine starts with finding the right ingredients. Every infectious agent has molecules, called antigens, that the immune system could potentially recognize and attack. So scientists must carefully consider which antigens should go into a vaccine.

28 Aug 2020

Researchers discover mechanisms underlying learning and memory formation in the brain

Seeking an answer, researchers at CHU Sainte-Justine Hospital and Université de Montréal have made a major discovery in understanding the mechanisms underlying learning and memory formation.

26 Aug 2020

MIT engineers create a focused approach to imaging neural activity

When neurons fire an electrical impulse, they also experience a surge of calcium ions. By measuring those surges, researchers can indirectly monitor neuron activity, helping them to study the role of individual neurons in many different brain functions.

26 Jun 2020

Mice study sheds light on how the brain links events to form a memory

A woman walking down the street hears a bang. Several moments later she discovers her boyfriend, who had been walking ahead of her, has been shot.

9 May 2020

Pittsburgh professor receives CAREER award to improve clinical applications of brain-computer interfaces

Using electrodes smaller than a human hair, researchers are able to connect mind to machine and interact with the human brain in revolutionary ways.

8 Apr 2020

High-speed microscope records the passage of millisecond electrical pulses through neurons

Electrical and chemical signals flash through our brains constantly as we move through the world, but it would take a high-speed camera and a window into the brain to capture their fleeting paths.

19 Mar 2020

Scientists use blue mushroom dye to develop fluorescent tool for detecting reactive oxygen species

A new fluorescent tool for detecting reactive oxygen species based on a chemical found in mushrooms has been developed by scientists at the University of Bath.

17 Dec 2019

The Acoustics of the Brain: Random-access 3D Microscopy in Neuroscience

Máté Marosi and Zsolt Iván discuss the use of acousto-optic microscopes to study neural networks in the brain, from cell bodies to dendrites, to tiny spines.

From Femtonics Ltd. 17 Dec 2019

Neuroscientists decode how visual cues can reorganize the activity of compass neurons

If you've ever woken up in the middle of the night to go to the bathroom and stumbled around in the dark, banging into walls or dressers in a room you've walked through countless times, you've experienced the effects of inadequately calibrated neurons.

21 Nov 2019

AI-based technique traces the shapes of active neurons faster than a human can

Biomedical engineers at Duke University have developed an automated process that can trace the shapes of active neurons as accurately as human researchers can, but in a fraction of the time.

12 Apr 2019

Mild cognitive impairment may be present in early stages of kidney disease

The link between brain dysfunction and advanced kidney disease was first noted in 1930, so it is not a new finding.

10 Apr 2019

Sounds and vibrations are quite similar for the brain, finds new study

We all know the feeling of a mobile phone vibrating in our hands when announcing an incoming call. If we perceive these vibrations so clearly, it is due to specialized receptors that transduce them into neural signals sent to our brain.

21 Mar 2019

Pitt study delves deeper into how electrical stimulation activates neurons

Electrical stimulation of the brain is common practice in neuroscience research and is an increasingly common and effective clinical therapy for a variety of neurological disorders. However, there is limited understanding of why this treatment works at the neural level.

8 Jan 2019

Montana State doctoral student receives grant for her work to improve neuroscience tool

A Montana State University doctoral student who is working on a way to improve a neuroscience tool that uses fluorescent proteins found in some jellyfish and coral has received a grant that will help fund her work.

17 Dec 2018

New study finds evidence that animals can judge time

Are you taking your time when feeding your pet? Fluffy and Fido are on to you -- and they can tell when you are dawdling.

24 Oct 2018

Neurons in the brain's primary visual cortex can reliably detect straight lines

Single neurons in the brain's primary visual cortex can reliably detect straight lines, even though the cellular makeup of the neurons is constantly changing, according to a new study by Carnegie Mellon University neuroscientists, led by Associate Professor of Biological Sciences Sandra Kuhlman.