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Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was developed and is being marketed by the pharmaceutical company Pfizer. It acts by inhibiting cGMP specific phosphodiesterase type 5, an enzyme that regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra). It is frequently called the 'blue pill'.

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

Generic version of Viagra could be the long-waited remedy for dogs with megaesophagus

Sildenafil, the generic version of the drug known as Viagra, could be the long-waited remedy for a group of dogs with a rare disorder called megaesophagus.

21 Feb 2022

Study examines whether viagra-like drug may be effective in treating vascular dementia

A new study, published today in Alzheimer's & Dementia, tested whether tadalafil, a drug closely related to Viagra, may be effective in treating people with vascular dementia.

9 Feb 2022

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Researchers at Albert Einstein College of Medicine have developed a topical drug that regenerates and restores the function of erectile nerves damaged by radical prostatectomy, the most common treatment for localized prostate cancer.

19 Apr 2021

Study examines the impact of Viagra drug advertising on birth rates

Many marketing studies have examined the impact of direct-to-consumer advertising of pharmaceuticals on sales and market shares. But in a new study, a researcher from The University of Texas at Dallas wanted to know whether drug advertising might have some unintended, population-level health consequences.

1 Oct 2020

Potency-enhancing drugs show ability to improve prognosis in patients with colorectal cancer

A new study from Lund University and Region Skåne in Sweden indicates that potency-enhancing PDE5 inhibitor drugs have an anti-cancer potential with the ability to improve the prognosis in patients with colorectal cancer.

17 Aug 2020

Study reports a change in why men seek help for sexual problems

Scientists report a change in why men seek help for sexual problems, with fewer men complaining about impotence (erectile dysfunction) and premature ejaculation, and more men, especially younger men, complaining about low sexual desire and curvature of the penis (Peyronie's disease).

19 Jul 2020

Newfound knowledge may prove valuable to understand human nerve cells

Researchers discover what's behind nature's perhaps largest erection - which is not that big PLANT BIOLOGY.

16 Jun 2020

Hormone blocker shocker: Drug costs 8 times more when used for kids

Dr. Sudeep Taksali, an orthopedic surgeon, became worried that his 8-year-old daughter had already grown taller than his 12-year-old son. And sometimes she had an attitude more befitting a teenager. Something seemed wrong.

24 Feb 2020

ED drug labels should inform patients about plant-based diet's ability to fight disease

Package labels for Viagra, Cialis, and other erectile dysfunction drugs should inform patients that ED is a sign of potentially fatal artery disease, according to a petition the Physicians Committee for Responsible Medicine filed with the Food and Drug Administration on Feb. 10. Between 18 and 30 million men in the United States have ED.

10 Feb 2020

Viagra may cause long lasting visual disturbances finds study

In a new study scientists have reported that Sildenafil or Viagra pills used for erectile dysfunction could lead to longer lasting visual disturbances than known before. The study titled, “Ocular Side Effects of Sildenafil That Persist Beyond 24 h—A Case Series,” was published in the latest issue of the journal Frontiers in Neurology.

9 Feb 2020

Scientists urge further caution on use of Viagra for fetal therapy

University of Manchester scientists investigating a possible treatment for fetal growth restriction, a condition in which babies grow poorly in the womb, have urged further caution on the use of Viagra.

17 Jan 2020

Viagra enables rapid and efficient hematopoietic stem cell mobilization in mice

The combination of two clinically approved drugs--Viagra and Plerixafor--rapidly and efficiently mobilizes blood stem cells from the bone marrow into the bloodstream in mice, researchers report October 10th in the journal Stem Cell Reports.

4 Oct 2019

Men with prostate cancer can have healthy sex lives after surgery

There's a perception that surgery to treat prostate cancer will spell the end of a man's sex life.

17 Sep 2019

New study welcomes TGA’s decision to step back from prohibiting poppers

Young gay and bisexual men are frequent users of alkyl nitrites, or poppers, but few show signs of addiction, risky consumption habits or other psychosocial problems, a study shows.

21 Jun 2019

Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Erectile dysfunction can affect a man's quality of life, but treatable

By age 50, nearly half of men experience some degree of erectile dysfunction. Advertisements for medications treating the condition have been all over mainstream media for years.

12 Jun 2019

Is it a feminist right to want more sex? One company thinks a pill is the answer

Studies have never defined a "normal" level of sexual desire. Despite that, there's a website and an online quiz to help you decide if you've got a problem. Called "Right to Desire," it brands libido as a feminist "right," and its home page offers the defiant, in-your-face prompt: "Yes, I want my desire back."

11 May 2019

UCI discovery may lead to mitigation of side effects caused by erectile dysfunction drugs

In a study published in Science Advances magazine, researchers from the University of California, Irvine have captured, for the first time, the full-length structure of the rod photoreceptor phosphodiesterase 6 (PDE6), an enzyme that plays an indispensable role in human vision.

5 Apr 2019