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Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Researchers compared the immunogenicity of or and reactogenicity to the BNT162b2 vaccine in Japanese adults and elders.

16 May 2022

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

A study conducted at the University of São Paulo's Medical School (FM-USP) in Brazil, with results reported in an article published in the journal Immunity & Ageing, shows that chronic obstructive pulmonary disease (COPD) leads to premature senescence (age-related impairment) of the immune system.

13 May 2022

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

A new study has longitudinally traced and profiled the CD8+ T cell responses after COVID-19 mRNA booster vaccination.

13 May 2022

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

In a recent study posted to the bioRxiv* preprint server, researchers characterized the development of multiple adenovirus-vectored and subunit recombinant protein severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine candidates.

12 May 2022

T-cell responses after COVID-19 and vaccinations

A new study published in the journal Frontiers in immunology examines the cell-mediated immunity in BNT162b2 COVID-19 mRNA vaccinated health care workers and COVID-19 patients.

12 May 2022

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

A new study has focussed on determining the clonality and levels of SARS-CoV-2-reactive CD4+ T cells in CCPs post-vaccination.

12 May 2022

Study shows reduced respiratory syncytial virus antibody levels in women of childbearing age and infants during the COVID-19 pandemic

A study demonstrated that the humoral immunity against the respiratory syncytial virus (RSV) has significantly reduced.

12 May 2022

Exploring simultaneous and sequential COVID-19 vaccine candidate

Researchers developed novel lipid nanoparticle (LNP)-based messenger ribonucleic acid vaccine formulations against three pathogenic coronaviruses.

10 May 2022

Scientists explore immunopathology of COVID-19

Researchers explored the interactions between severe acute respiratory syndrome coronavirus 2 and the host in the development of COVID-19.

6 May 2022

Effects of diet on COVID-19 outcomes

A new study explores the effects of diet on COVID-19 outcomes.

5 May 2022

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

In a recent study posted to the Research Square* preprint server, researchers tested the safety and immunogenicity of a third dose of coronavirus disease 2019 (COVID-19) prototype messenger ribonucleic acid (mRNA)-1273 versus a variant vaccine and a bivalent vaccine formulation.

5 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

SARS-CoV-2-specific T cells are broader after vaccination than after infection

In a recent study published in the Nature Microbiology journal, researchers investigated the characteristics of coronavirus disease 2019 (COVID-19) infection in convalescent and vaccinated individuals.

1 May 2022

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to SARS-CoV-2.

29 Apr 2022

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

Superior T-cell immunity in COVID vaccinated

A recent study published in the journal Public Library of Science (PLOS) ONE presented the T cell and humoral immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infection against the SARS-CoV-2 original and mutant strains.

27 Apr 2022

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

A new study examined the protective effect of the mRNA booster vaccine against the SARS-CoV-2 Omicron variant in 21-month-old mice.

26 Apr 2022

Study explores SARS-CoV-2 antibody responses in mild COVID-19 cases

In a new study, researchers evaluated antibody responses in mild cases of coronavirus disease 2019.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

T cell responses were measured to three SARS-CoV-2-associated antigens, as well as the endemic coronaviruses HCoV-OC43 and HCoV-NL63.

25 Apr 2022

CD4 News and Research

Exploring age-associated differences in T lymphocyte immune responses after BNT162b2 vaccination

Chronic obstructive pulmonary disease leads to premature senescence of the immune system

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

An Ad5 vectored COVID vaccine expressing an S1-N fusion protein

T-cell responses after COVID-19 and vaccinations

Clonality and magnitude of SARS-CoV-2-reactive CD4+ T cells in COVID-19 convalescent patients after vaccination

Study shows reduced respiratory syncytial virus antibody levels in women of childbearing age and infants during the COVID-19 pandemic

Exploring simultaneous and sequential COVID-19 vaccine candidate

Scientists explore immunopathology of COVID-19

Effects of diet on COVID-19 outcomes

Efficacy and safety of a 3rd dose of mRNA-1273 SARS-CoV-2 vaccine

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

SARS-CoV-2-specific T cells are broader after vaccination than after infection

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

How do mosquito bites affect immunity?

Superior T-cell immunity in COVID vaccinated

mRNA booster vaccination found to protect aged mice against the Omicron variant of SARS-CoV-2

Study explores SARS-CoV-2 antibody responses in mild COVID-19 cases

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

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