Delirium News and Research

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Delirium is a mental state in which a person is confused, disoriented, and not able to think or remember clearly. The person may also be agitated and have hallucinations, and extreme excitement.

New website provides information to help lower anxiety before outpatient surgery in children

A newly developed website provides parents and children with individualized information and support -- based on factors like coping style and levels of worry and fear -- to help lower anxiety before outpatient surgery in children, according to a pair of articles in the April issue of Anesthesia & Analgesia.

6 Apr 2015

Geriatric consultation could improve care for elderly patients admitted for traumatic injuries

Elderly patients who are admitted to the hospital for monitoring and surgical treatment of traumatic injuries could have better geriatric care if medical teams took one extra step—offering geriatric consultation, according to new research findings from surgical and geriatric medicine teams at the Ronald Reagan University of California at Los Angeles Medical Center.

19 Feb 2015

Scientists find eight different types of schizophrenia

Scientists from the universities of Granada (Spain) and Washington in St Louis (US) have found that there is not a single type of schizophrenia, but that it consists of a group made up of eight genetically different types of diseases, each of which presents its own set of symptoms.

4 Feb 2015

Alzheimer's drug Aricept (donepezil) linked to serious side effects

New warnings have been added to the prescribing information for the Alzheimer's drug Aricept (donepezil) advising of the risk of two rare but potentially serious conditions: muscle breakdown (rhabdomyolysis) and a neurological disorder called neuroleptic malignant syndrome (NMS).

21 Jan 2015

FDA approves RYTARY for Parkinson's disease treatment

Impax Pharmaceuticals, a division of Impax Laboratories, Inc., today announced that the U.S. Food and Drug Administration approved RYTARY, an extended-release oral capsule formulation of carbidopa-levodopa, for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication and / or manganese intoxication.

8 Jan 2015

New guideline now available to help prevent, treat delirium in older patients

A new guideline is available to help health care providers prevent and treat one of the most common postoperative complications in older patients, delirium, which is an episode of sudden confusion.

27 Nov 2014

BIDMC investigators develop three-minute assessment that identifies delirium in older hospital patients

Delirium is a state of confusion that develops suddenly, often following an acute medical illness, a surgical procedure or a hospitalization. Although delirium is estimated to complicate hospital stays for over 2.5 million elderly individuals in the U.S. each year, this common condition often goes undetected. The end result can be serious complications with sometimes devastating consequences for vulnerable hospitalized elders.

21 Oct 2014

Research roundup: Malpractice reforms and doctors' practice; Medicaid expansion's effect

Defensive medicine is considered by many to be a major source of wasteful medical spending in the United States.

17 Oct 2014

Study: Nursing home care quality not associated with risk of hospital readmission or death

Nursing home care quality does not impact the likelihood of patients being readmitted to the hospital or dying within 30 days of discharge from hospital to nursing home, according to a new analysis of Medicare data and nursing home performance measures by Penn Medicine researchers.

16 Oct 2014

Nurse-led initiatives reduce length of stay, improve patient outcomes in Philadelphia hospitals

Recent nurse-led initiatives addressing some of critical care's most pressing challenges resulted in shorter average lengths of stay and other positive patient and fiscal outcomes in seven Philadelphia-area hospitals.

16 Oct 2014

Study: Benzodiazepine sedatives may increase death risk in patients receiving mechanical ventilation

Sedation is frequently required for mechanically ventilated intensive care unit (ICU) patients to reduce anxiety, provide comfort, and assist in providing optimal respiratory support.

1 Oct 2014

Survey finds low awareness about risks of cognitive side effects following surgery

Postsurgical cognitive side effects can have major implications for the level of care, length of hospital stay, and the patient's perceived quality of care, especially in elderly and fragile patients. A nationwide survey of Swedish anesthesiologists and nurse anesthetists has found there is low awareness of the risks of cognitive side effects following surgery.

19 Aug 2014

Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Drugs widely prescribed to the elderly could be responsible for a decline in cognitive and physical function according to research from the University of East Anglia and the Regenstrief Institute.

31 Jul 2014

Stimulating specific brain pathway may induce active emergence from anesthesia

Researchers may be one step closer to better understanding how anesthesia works. A study in the August issue of Anesthesiology, the official medical journal of the American Society of Anesthesiologists- (ASA-), found stimulating a major dopamine-producing region in the brain, the ventral tegmental area (VTA), caused rats to wake from general anesthesia, suggesting that this region plays a key role in restoring consciousness after general anesthesia.

23 Jul 2014

DBS improves motor and non motor symptoms of patients with early Parkinson's disease

Deep brain stimulation (DBS) has become a well-recognized non-pharmacologic treatment that improves motor symptoms of patients with early and advanced Parkinson's disease.

26 Jun 2014

Two Regenstrief investigators receives Career Development K23 Awards from NIH

Two Regenstrief Institute investigators and Indiana University Center for Aging Research scientists -- Michael LaMantia, M.D., MPH, and Noll L. Campbell, PharmD -- have each received five-year Mentored Patient-Oriented Research Career Development K23 Awards from the National Institute on Aging at the National Institutes of Health.

13 Jun 2014

Critically ill patients receiving steroids in ICU are more likely to develop delirium

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital’s intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.

28 May 2014

New understanding of toxicity levels of chemotherapy regimens used for early stage breast cancer

Oncologists now have a new understanding of the toxicity levels of specific chemotherapy regimens used for women with early stage breast cancer, according to research from The University of Texas MD Anderson Cancer Center.

28 May 2014

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital's intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.

28 May 2014

Norwegian Accident and Emergency departments not designed for elderly patients

Norwegian Accident and Emergency departments are not designed for elderly patients, and their staff often lack geriatric experience.

20 May 2014

Delirium News and Research

Further Reading

New website provides information to help lower anxiety before outpatient surgery in children

Geriatric consultation could improve care for elderly patients admitted for traumatic injuries

Scientists find eight different types of schizophrenia

Alzheimer's drug Aricept (donepezil) linked to serious side effects

FDA approves RYTARY for Parkinson's disease treatment

New guideline now available to help prevent, treat delirium in older patients

BIDMC investigators develop three-minute assessment that identifies delirium in older hospital patients

Research roundup: Malpractice reforms and doctors' practice; Medicaid expansion's effect

Study: Nursing home care quality not associated with risk of hospital readmission or death

Nurse-led initiatives reduce length of stay, improve patient outcomes in Philadelphia hospitals

Study: Benzodiazepine sedatives may increase death risk in patients receiving mechanical ventilation

Survey finds low awareness about risks of cognitive side effects following surgery

Anti-cholinergic drugs could be responsible for decline in cognitive, physical function in elderly patients

Stimulating specific brain pathway may induce active emergence from anesthesia

DBS improves motor and non motor symptoms of patients with early Parkinson's disease

Two Regenstrief investigators receives Career Development K23 Awards from NIH

Critically ill patients receiving steroids in ICU are more likely to develop delirium

New understanding of toxicity levels of chemotherapy regimens used for early stage breast cancer

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

Norwegian Accident and Emergency departments not designed for elderly patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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