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UAlberta chemistry professor develops revolutionary neuroscience tools

UAlberta chemistry professor Robert Campbell is developing new ways to see and manipulate the activity of neurons in the brain, which could revolutionize the way we understand the organ that controls most of the activities of the body.

11 Sep 2017

G:BOX Chemi XX6 imaging system used to analyze how bacteria react to stressors

Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at the University of Warwick to rapidly and accurately analyze how Gram positive bacteria react to stressors.

From Syngene 8 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Researchers explore causal link between perirhinal neurons and mnemonic judgment of objects

Cognitive neuroscience research on non-human primates demonstrated that judgments of whether humans have previously seen or not seen an object are causally determined by neuronal signals generated in the temporal cortex of the brain. The findings are published in Science (August 2017).

1 Sep 2017

Scientists succeed in teaching robots to perform challenging brain technique

Whole-cell patch clamp electrophysiology, or whole-cell recording (WCR), is the gold-standard technique for studying the behaviour of brain cells called neurons under different brain states such as stress or learning.

31 Aug 2017

MIT engineers devise automated approach to monitor neurons

Recording electrical signals from inside a neuron in the living brain can reveal a great deal of information about that neuron's function and how it coordinates with other cells in the brain.

30 Aug 2017

Genetics of digestion stayed remarkably the same from fishes to humans, research shows

Scientists have discovered a network of genes and genetic regulatory elements in the lining of the intestines that has stayed remarkably the same from fishes to humans. Many of these genes are linked to human illnesses, such as inflammatory bowel diseases, diabetes and obesity.

30 Aug 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Research findings potentially open door to new treatments for eye trauma and retinal disease

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease.

28 Aug 2017

Nanomaterial wrap for improved tissue imaging

Researchers at Tokai University describe in Advanced Materials how wrapping biological tissue in a nanosheet of a particular organic material results in high-quality microscopy images. Application of the wrap prevents the sample from drying out, and hence from shrinking, enabling larger image-recording times.

20 Aug 2017

Researchers develop set of tools to trace path of proteins linked to Parkinson's disease

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease progress, misfolded proteins clump together in neurons, recruiting normal proteins in the cell to also misfold and aggregate.

4 Aug 2017

Research suggests novel approach for encouraging regeneration in mouse retina

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows.

27 Jul 2017

Fluorescent proteins found in jellyfish shed new light on DNA copying

Using these proteins, originally found in jellyfish to make them glow, the team where able to focus laser beams on the brightly lit proteins and track them inside a bacteria that normally lives inside the human gut.

28 Jun 2017

Researchers develop new technique to capture neuron activity

Many cognitive processes, such as decision-making, take place within seconds or minutes. Neuroscientists have longed to capture neuron activity during such tasks, but that dream has remained elusive -- until now.

27 Jun 2017

Japanese scientists show how male pheromone enhances female sexual behavior in mice

A study by a group of Japanese scientists showed how a male pheromone in mice enhances sexual behaviors in females--and how it may enhance a different behavior, aggression, in males -- by identifying distinct neural circuits and neurons that generate a particular behavioral response to specific chemical signals.

22 Jun 2017

Researchers identify brain cells that drive fruit flies’ food choices based on nutrition needs

Using fruit flies, Johns Hopkins researchers say they have identified a specific and very small set of brain cells -- dubbed dopamine wedge neurons -- responsible for driving the insects' food preferences toward what they need, rather than what they like.

10 May 2017

Research findings reveal new approach to prevent age-related obesity

The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves - fatty deposits - by generating heat in a process known as thermogenesis.

4 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

Synchronized voltage rhythms in SCN could play role in maintaining the body’s circadian clock

Cells in the brain's master circadian clock synchronize voltage rhythms despite asynchronous calcium rhythms, which might explain how a tissue-wide rhythm is maintained.

24 Apr 2017

Environmental 'memory' can be passed on in genes for many generations

Led by Dr Ben Lehner, group leader at the EMBL-CRG Systems Biology Unit and ICREA and AXA Professor, together with Dr Tanya Vavouri from the Josep Carreras Leukaemia Research Institute and the Institute for Health Science Research Germans Trias i Pujol, the researchers noticed that the impact of environmental change can be passed on in the genes for many generations while studying C. elegans worms carrying a transgene array - a long string of repeated copies of a gene for a fluorescent protein that had been added into the worm genome using genetic engineering techniques.

20 Apr 2017