Glycoprotein News and Research

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Using metal nanoparticles to fight SARS-CoV-2

A recent review article looks at the potential of nanotechnology in fighting severe acute respiratory syndrome 2 (SARS-CoV-2), with several possibilities of strategies in therapeutics, vaccines, and prevention.

25 Nov 2021

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Researchers conducted a study on COVID-19 convalescent patients and post-vaccinated populations to identify the minimal levels of antibody required to protect against SARS-CoV-2 infection.

24 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Interferon beta versus the SARS-CoV-2 Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the difference in replication efficiency or IFN sensitivity of the four VOCs.

22 Nov 2021

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

A team of researchers describes the presence of PDCoV strains in plasma samples of three Haitian children with acute undifferentiated febrile illness.

22 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

Structure of SARS-CoV-2 spike protein postfusion

A new study published in PNAS proposes a higher resolution in situ structure of the SARS-CoV-2 spike protein in its postfusion state.

18 Nov 2021

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

In the current study, researchers compare the IFITM sensitivities of major SARS-CoV-2 VOCs.

17 Nov 2021

New atomic-level insight of SARS-CoV-2 within a respiratory aerosol

In a paradigm-shifting paper currently available on the bioRxiv* preprint server, the researchers have dramatically extended the possibilities of computational microscopy in order to better understand both structure and dynamics of respiratory aerosols laden with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Nov 2021

Can COVID-19 vaccination lead to neurological complications?

A new review article discusses the neurological side effects due to SARS-CoV-2 vaccination.

14 Nov 2021

Partial resistance to neutralizing antibodies and enhanced transmissibility of SARS-CoV-2 Delta variant

A new study estimates the efficacy of the immune response induced by vaccination and natural COVID-19 infection against the Kappa and Delta lineages.

14 Nov 2021

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

A new study evaluates the safety, immunogenicity, and efficacy of the BNT162b2 in children who were 5 to 11 years of age.

11 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Studying influenza A virus and peptide interactions with electrically controllable DNA nanoconstructs

German scientists used DNA nanolevers to target the interaction between a peptide known as PeB and influenza A.

3 Nov 2021

Humoral immunity following heterologous and homologous COVID-19 vaccination regimens

Researchers sought to analyze immune responses after homologous vaccinations or after heterologous Vector/mRNA vaccinations, with respect to anti-COVID-19 immune responses and the development of autoantibodies.

3 Nov 2021

SARS-CoV-2 neutralizing antibodies discovered in a 20-year-old human antibody library

In an article published in the open-access journal Advance Engineering, a multinational team of researchers reported the selection and characterization of 3 potent SARS-CoV-2 antibodies - S-E6, S-B8, and S-D4 - from a pre-COVID-19 human combinatorial antibody library that was established 20 years ago.

3 Nov 2021

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

A new study aimed to identify several potent neutralizing RBD-directed and NTD-directed mAbs that used a nanoparticle displaying the S glycoprotein to capture SARS-CoV-2-specific B cells.

2 Nov 2021

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

A recent study published in the journal Cellular & Molecular Immunology shows that a new A.30 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can evade vaccine-induced antibodies and might spread outside the lungs extraordinarily well, with important implications for our public health response.

1 Nov 2021

Structure of human-infecting canine coronavirus HuPn-2018 spike glycoprotein

As CCoV-HuPn-2018 has been recently isolated in a child's respiratory swab, researchers from the University Of Washington have been examining the structure of the virus.

28 Oct 2021

Glycoprotein News and Research

Using metal nanoparticles to fight SARS-CoV-2

Similar antibody responses to spike protein in COVID-19 survivors and vaccine recipients

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Interferon beta versus the SARS-CoV-2 Delta variant

Study shows porcine deltacoronavirus (PDCoV) is capable of zoonotic transfer

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

Structure of SARS-CoV-2 spike protein postfusion

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

New atomic-level insight of SARS-CoV-2 within a respiratory aerosol

Can COVID-19 vaccination lead to neurological complications?

Partial resistance to neutralizing antibodies and enhanced transmissibility of SARS-CoV-2 Delta variant

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Study shows 90.7% efficacy for the BNT162b2 COVID vaccine in 5-11 year-olds

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Studying influenza A virus and peptide interactions with electrically controllable DNA nanoconstructs

Humoral immunity following heterologous and homologous COVID-19 vaccination regimens

SARS-CoV-2 neutralizing antibodies discovered in a 20-year-old human antibody library

Isolation of potent neutralizing monoclonal antibodies using nanoparticles displaying SARS-CoV-2 S glycoprotein

Emerging SARS-CoV-2 variant A.30 efficiently evades vaccine-induced immunity

Structure of human-infecting canine coronavirus HuPn-2018 spike glycoprotein

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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