Omicron News and Research

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New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Have a cough, sore throat and congestion? Any number of respiratory viruses could be responsible. Conventional tests can identify certain likely culprits by relying on chemical reactions, but some researchers want to swap chemistry for electrical changes sensed by nanomaterials.

28 Mar 2023

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

Researchers in the US examined the neutralization evasion and receptor affinity properties of SARS-CoV-2 Omicron BA.2.75 sub-variants.

28 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Researchers investigated the effects of the booster coronavirus disease 2019 (COVID-19) vaccine during pregnancy on COVID-19-related hospitalization rates among infants.

27 Mar 2023

Chronological and biological age may be important determinants of vaccine-preventable outcomes

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Parsing chronological and biological age effects on vaccine responses."

27 Mar 2023

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

In a recent study published in Nature's Communications Biology journal, researchers in the United States of America (USA) employed next-generation sequencing (NGS) data to assess the rise in reinfections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

23 Mar 2023

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers in France compared the efficacy of Pfizer-BioNTech Original/BA.4-5 bivalent vaccine compared to messenger ribonucleic acid (mRNA) Original (ancestral) monovalent vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

In a recent study published in the JAMA Health Forum, researchers in the United States estimated the reduction in coronavirus disease 2019 (COVID-19) mortality rates after the Paxlovid rollout.

22 Mar 2023

Emergence and persistency of SARS-CoV-2 Omicron BA.2.3.7 in Taiwan

Researchers utilize whole-genome surveillance to monitor community transmission and evolution of SARS-CoV-2 in Taiwan.

22 Mar 2023

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Researchers assess SARS-CoV-2 spike protein-specific immunological memory among unvaccinated and vaccinated convalescents.

22 Mar 2023

Study reveals why COVID-19 subvariants spread rapidly among previously infected people

The COVID-19 pandemic has killed nearly 7 million people worldwide (1.1 million in the United States) and severely harmed many millions more, though vaccines and antiviral treatments measurably reduced the potential loss of life and health.

22 Mar 2023

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2.

22 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Prior COVID and vaccination generate superior hybrid immunity

In a recent article published in the journal Science Translational Medicine, researchers in France performed a long-term longitudinal analysis to demonstrate the benefits of hybrid immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), i.e., induced by viral infection followed by vaccination.

21 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Researchers evaluate vaccine effectiveness for two, three, and four doses of COVID-19 mRNA first-generation vaccines.

21 Mar 2023

Study provides insights on stability of SARS-CoV-2 in biological fluids of animals

In a recent study published in the Viruses journal, researchers assessed the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among biological fluids found in animals.

21 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

COVID-19 has caused significant global panic after its rapid emergence more than 3 years ago. Although we now have highly effective vaccines against the SARS-CoV-2 virus, which causes COVID-19, scientists continue to study emerging SARS-CoV-2 variants in order to safeguard public health and devise global preventive strategies against emerging variants.

20 Mar 2023

Omicron News and Research

New nanomaterials-based sensor detects flu and COVID-19 in just 10 seconds

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

New study suggests broad neutralizing antibody could provide three years of COVID protection

COVID-19 infant hospitalizations reduced by a 3rd maternal vaccine dose during pregnancy

Chronological and biological age may be important determinants of vaccine-preventable outcomes

Reinfections with Omicron VOCs occur more frequently and over shorter intervals

Monovalent vs. bivalent vaccines – Which is more effective against SARS-CoV-2?

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

Higher Paxlovid uptake in winter 2022 could have prevented nearly 5,000 deaths

Emergence and persistency of SARS-CoV-2 Omicron BA.2.3.7 in Taiwan

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Study reveals why COVID-19 subvariants spread rapidly among previously infected people

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Prior COVID and vaccination generate superior hybrid immunity

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Study provides insights on stability of SARS-CoV-2 in biological fluids of animals

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

New SARS-CoV-2 Omicron XBB.1.5 variant has high transmissibility and infectivity, study finds

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