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Ensuring raw material quality in drug production and manufacturing

In this interview, Thermo Fisher Scientific discusses how to ensure the high quality of raw material in the drug production and manufacturing pipeline.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 12 Oct 2023

Accelerating drug discovery with analytical R&D solutions

In this interview, Thermo Fisher Scientific discusses how to accelerate drug discovery through analytical R&D.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 12 Oct 2023

Is your DNA steering you towards a vegetarian diet?

Researchers using the UK Biobank identified genetic markers linked to strict vegetarianism, revealing potential connections between vegetarianism, lipid metabolism, and brain activity. The study highlighted genes, particularly those active in the brain and related to cholesterol movement, as influential in an individual's inclination towards a vegetarian lifestyle.

9 Oct 2023

Researchers explore immunomodulating targets for improving glioblastoma therapies

Researchers have delved into the intricate heterogeneity of glioblastoma, a notoriously aggressive brain tumor, using advanced single-cell RNA sequencing and innovative zebrafish avatars. Their findings spotlighted the LGALS1 gene's role in immunosuppression and suggested potential therapeutic avenues for personalized GBM treatment.

8 Oct 2023

Trump misplaced blame when he said drug shortages were Biden’s fault

"Under 'Crooked Joe' Biden, there has been a catastrophic increase in shortages of essential medicines."

6 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Sphere Fluidics’ Cyto-Mine system selected by FairJourney Biologics to advance cell line development workflows

Sphere Fluidics, a company developing single cell analysis systems underpinned by its patented picodroplet technology, today announced the Cyto-Mine® platform has been selected by FairJourney Biologics, a world leading end-to-end antibody partner, providing integrated services across antibody discovery, engineering, and production, to expand its cell line development capabilities.

From Fluidic Sciences and Sphere Bio 4 Oct 2023

Stereotactic radiation therapy offers new hope for older adults with inoperable kidney cancer

Older adults diagnosed with kidney tumors that are not suitable for surgery may benefit from targeted, high-dose radiation, a new study from Australian and Dutch researchers suggests.

3 Oct 2023

Panacol’s Special Adhesives for Medical Wearables

Wearable patient monitoring devices are worn directly on the body and are being used in increasing numbers

From Panacol-Elosol GmbH 27 Sep 2023

Innovations in baculovirus–insect cell expression systems

The baculovirus–insect cell expression system—insect cells used in conjunction with the baculovirus expression vector system (BEVS)— remains a crucial technology for manufacturing large and complex proteins. This eukaryotic expression system offers inherent safety, ease of scale-up, flexible product design, and versatility for a broad range of proteins.

From Sino Biological Inc. 20 Sep 2023

Mitochondrial GTP metabolism acts through mitochondrial dynamics factors to regulate reproductive aging

Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.

18 Sep 2023

Researchers discover backup protein quality control mechanism

Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail.

14 Sep 2023

Autobio's Autof MS Series has obtained the EU IVDR Class C registration certificate

Autobio’s Autof MS Series has obtained the EU IVDR Class C registration certificate.

From Autobio 11 Sep 2023

‘Like a Russian roulette’: US military firefighters grapple with unknowns of PFAS exposure

A U.S. military firefighter for 32 years, Kurt Rhodes trained and performed his duties with aqueous film forming foam, or AFFF — a highly effective fire suppressant that he never knew contained PFAS chemicals, now known to be harmful to human health.

7 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

CN Bio and LifeNet Health LifeSciences partner to supply validated primary human cells for microphysiological systems

Partnership to provide customers with direct access to portfolio of highly characterized hepatic cells to recreate advanced Liver-on-a-Chip assays.

From CN Bio 6 Sep 2023

Outbreak of piercing infections in Australia traced to contaminated aftercare solution

Researchers in New South Wales, Australia, used genomic sequencing to trace an outbreak of Pseudomonas aeruginosa infections following ear piercings to a specific batch of aftercare solution. The study led to a recall of the product and improvements in manufacturing standards, successfully reducing the number of infections.

4 Sep 2023

Intellegens and CPI awarded £1.6m Innovate UK grant to advance manufacture of oligonucleotide therapeutics with machine learning

Intellegens, a company applying machine learning (ML) to accelerate innovation in R&D, today announced that it has secured a £1.6m grant from Innovate UK, part of UK Research and Innovation (UKRI), to apply ML in the emerging field of oligonucleotide therapies.

30 Aug 2023

Same cellular mechanism implicated in cystic fibrosis and rare disease cystinosis

University of Michigan researchers have discovered that the same cellular mechanism involved in a form of cystic fibrosis is also implicated in a form of a rare disease called cystinosis.

28 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.