Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

The recent emergence of immunotherapy has marked a sea change in research and care for many forms of cancer, bringing new hope to patients and families around the world. For those who respond to treatment, the results can be dramatic.

10 Apr 2019

Study finds disparities in lung cancer treatments among Asian communities

study from the University of Southern California, Keck School of Medicine, sought to examine possible health disparities in the treatment of lung cancer within the Asian community in the U.S.

9 Apr 2019

High-dose standard radiation treatment well-tolerated by patients with centrally located NSCLC

Stereotactic Body Radiotherapy, a high-dose, precisely delivered radiotherapy, is considered the standard treatment for patients with medically inoperable, node-negative, non-small cell lung cancer.

5 Apr 2019

New combination therapy found to be well tolerated in patients with aggressive brain tumor

A phase I clinical trial that set out to assess the safety of a new combination therapy for a type of aggressive brain tumour has found the treatment to be well tolerated in patients.

30 Mar 2019

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

While non-small cell lung cancer is the more common form of lung cancer and attracts the lion's share of the research funding, recent developments in small cell lung cancer may be shifting that slightly.

29 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Study provides new pathway for controlling inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

22 Mar 2019

Lung cancer survivor recounts her lifetime struggles

By any measure, lung cancer patients have it rough. But Maryland resident and special education teacher Montessa Lee has been through a particularly arduous ordeal.

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Prophylactic cranial irradiation used as standard approach for patients with NSCLC

Prophylactic cranial irradiation, a technique used to prevent the clinical development of brain metastases, is established as a standard approach for many patients with small cell lung cancer after initial therapy.

19 Mar 2019

Precision cancer drugs spark powerful immune response and boost effects of immunotherapy

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals.

11 Mar 2019

Increased muscle mass could save your life

As far back as Ancient Greece, a sculptured physique has been heralded as the pinnacle of physical perfection. But now, researchers from Japan have found that increased muscle mass doesn't just make you look good, it could literally save your life.

4 Mar 2019

New microfluidic device can isolate individual cancer cells from blood samples

Researchers at the University of Illinois at Chicago and Queensland University of Technology of Australia, have developed a device that can isolate individual cancer cells from patient blood samples. The microfluidic device works by separating the various cell types found in blood by their size.

26 Feb 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Harnessing the evolutionary games played by cancer cells to advance therapies

Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression.

19 Feb 2019

Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models

Researchers at The University of Texas MD Anderson Cancer Center have discovered that a combination of immune checkpoint blockade and targeted therapies that block normal DNA damage repair achieved significant tumor regression in mouse models of small cell lung cancer, suggesting a promising new approach for treating patients with this aggressive cancer.

18 Feb 2019

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer.

14 Feb 2019

Trojan Horse approach to cancer therapy shows promise

A new form of cancer fighting drug has been developed using the principles of the “Trojan Horse”.

11 Feb 2019

New model sheds light on how small cell lung cancer is initiated

Scientists from Weill Cornell Medicine have developed a stem-cell-based model of small cell lung cancer that will help them understand how the disease is initiated and how it progresses.

11 Feb 2019

Drug treating breast cancer may be effective in treating lung and ovarian cancer

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare and one common form.

5 Feb 2019

Small Cell Lung Cancer News and Research

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

Study finds disparities in lung cancer treatments among Asian communities

High-dose standard radiation treatment well-tolerated by patients with centrally located NSCLC

New combination therapy found to be well tolerated in patients with aggressive brain tumor

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Study provides new pathway for controlling inflammation

Lung cancer survivor recounts her lifetime struggles

City of Hope exhibits current studies and data on cancer therapies at AACR

Prophylactic cranial irradiation used as standard approach for patients with NSCLC

Precision cancer drugs spark powerful immune response and boost effects of immunotherapy

Increased muscle mass could save your life

New microfluidic device can isolate individual cancer cells from blood samples

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Harnessing the evolutionary games played by cancer cells to advance therapies

Combination of PARP inhibitor and immunotherapy results in tumor regression in SCLC mouse models

Novel approach uses small amounts of tissue to quantify PD-L1 expression levels in tumors

Trojan Horse approach to cancer therapy shows promise

New model sheds light on how small cell lung cancer is initiated

Drug treating breast cancer may be effective in treating lung and ovarian cancer

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