Twenty-five million Americans suffer from ulcers. An ulcer is a sore or hole in the lining of the stomach or duodenum (the first part of the small intestine). People of any age can get an ulcer and women are affected just as often as men.
Helicobacter pylori (H. pylori) is a bacterium that lives on the lining of the stomach. Although we used to think that spicy food, acid, and stress were the major causes of ulcers, we now know that nine out of ten ulcers are caused by H. pylori. Medicines that reduce stomach acid may make you feel better, but your ulcer may come back. Here's the good news: Since most ulcers are caused by this bacterial infection, they can be cured with the right antibiotics.
Patients with diseases such as diabetes suffer from painful wounds that take a long time to heal making them more susceptible to infections that could even lead to amputations. A*STAR's discovery paves the way for therapeutics to improve healing of such chronic wounds, which are a significant burden to patients.
Results from a randomized, open-label phase III trial suggest that a combination cream of halometasone and fusidic acid reduces symptoms of eczema to a similar degree to a betamethasone and neomycin sulphate cream, but is more effective at treating infected lesions.
"During my visit to the Médecins Sans Frontières [MSF] Buruli ulcer ward in Cameroon it was wonderful to see the amazing care that the patients receive on a daily basis: antibiotics, state of the art dressings, physiotherapy to help prevent deformities, free food and medicines, and surgery when required," Daniel O'Brien, a specialist adviser with MSF-UK focusing on HIV/AIDS, tuberculosis and Buruli ulcer, writes in the BMJ Group Blogs.
New findings from two double-blind, randomized trials, RE-MEDY and RE-SONATE, show that dabigatran 150 mg twice daily reduces the risk of recurrent venous thromboembolism (VTE).
The first patient has been enrolled in the phase I/II REPARO study, the first international clinical trial evaluating the ophthalmological use of a topical solution of recombinant human Nerve Growth Factor (rhNGF) for the treatment of moderate to severe neurotrophic keratitis (NK).
The federal government invested more than $25 billion in health information technology (IT) as a result of the American Reinvestment and Recovery Act; yet, little is known about how IT applications improve patient safety and protect their privacy. Now, a University of Missouri nursing informatics expert suggests that sophisticated IT leads to more robust and integrated communication strategies among clinical staff, which allows staff to more efficiently coordinate care and better protect patient privacy.
A review of patients with oral eosinophilic ulcers suggests that the lesions should be considered a reactive, local condition rather than a CD30+ lymphoproliferative disorder.
A single nucleotide polymorphism in the cytochrome P450 2C gene cluster influences the risk for peptic ulcer disease in people taking non-steroidal anti-inflammatory drugs, a study reveals.
Researchers report that the addition of Achilles tendon lengthening to procedures for managing diabetic forefoot and midfoot ulceration seems warranted.
Every 30 seconds somebody in the world is amputated as a consequence of foot complication due to diabetes. A new study at Sahlgrenska Academy, University of Gothenburg, Sweden, confirmes that shoe inserts, podiatry, regular checkups and other simple interventions can reduce the number of amputations by more than 50%.
WHO reports unprecedented progress against 17 neglected tropical diseases, thanks to a new global strategy, a regular supply of quality assured, cost-effective medicines and support from global partners.
Tibial artery calcification is a significant risk factor for foot ulcers in patients with Type 2 diabetes, research suggests.
Critically ill patients in hospital intensive care units (ICUs) are routinely prescribed acid-suppressive medications to reduce their risk of developing stress ulcers and gastrointestinal bleeding, both of which can result from being in a stressful environment and from being intubated. Over the years, this routine practice has often been extended to patients outside the ICU, despite a lack of evidence that this population is at significant risk of these complications.
Outcomes among patients with acute upper gastrointestinal bleeding can be improved by employing a restrictive transfusion strategy that raises the threshold for the transfusion of red cells, the results of a Spanish study indicate.
Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. prescribing information for Pradaxa (dabigatran etexilate mesylate) capsules was updated to include a contraindication related to use in patients with mechanical prosthetic heart valve replacement.
Chock-full of Omega-3 fatty acids and antioxidants, fish oil can help lower blood pressure, reduce inflammation in the skin and joints, and promote healthy fetal development. Now a Tel Aviv University researcher has found that it has a positive effect on bedsores, too.
Delayed wound healing is a major complication of diabetes because the physiological changes in tissues and cells impair the wound healing process. This can result in additional disease outcomes such as diabetic foot ulcer, a significant cause of morbidity in the growing population of diabetic patients. A new study has found that topically applied simvastatin accelerates wound healing in diabetic mice, suggesting important implications for humans with diabetes.
The skin is the most versatile of our organs: It protects the body from environmental effects, contributes to the body's immune system and supports metabolic functions such as breathing.
The U.S. Food and Drug Administration (FDA) today announced the results of a Mini-Sentinel assessment that indicates bleeding rates associated with new use of Pradaxa (dabigatran etexilate mesylate) capsules do not appear to be higher than bleeding rates associated with new use of warfarin, which is consistent with observations from the pivotal RE-LY trial.
Researchers report that in the USA, Medicare spending on patients with diabetic foot disease varies significantly between different hospital referral regions.
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