Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

New understanding of Sly Syndrome

The scientist who discovered “Sly Syndrome” nearly four decades ago and a team of colleagues at Saint Louis University are a step closer to finding an approach to treat the rare genetic disease.

26 Jul 2007

ZARS starts phase 3 trial of ThermoProfen

ZARS, Inc., has announced that it commenced the first of two Phase 3 clinical trials of ThermoProfen in patients with mild to moderate osteoarthritis (OA) of the knee on June 26, 2007.

26 Jul 2007

Nastech Pharmaceutical Co. issued patents for parathyroid hormone nasal spray for treatment of osteoporosis

Nastech Pharmaceutical Company Inc. has announced the issuance of two U.S. patents by the U.S. Patent and Trademark Office.

18 Jul 2007

FDA approves Extina for seborrheic dermatitis

Stiefel Laboratories, Inc. has announced that the U.S. Food and Drug Administration (FDA) has approved its new drug application for Extina (ketoconazole) Foam, 2% for the treatment of seborrheic dermatitis.

18 Jul 2007

Phosphatidylglycerol holds promise for psoriasis, age-related skin damage

The body may hold a secret to normalizing skin cell growth that is over zealous in psoriasis and non-melanoma skin cancers and too slow in aging and sun-damaged skin, researchers say.

29 Jun 2007

Researchers increase in vivo lifetime of nanoparticles

Researchers at the University of California, Santa Barbara have discovered that attaching polymeric nanoparticles to the surface of red blood cells dramatically increases the in vivo lifetime of the nanoparticles.

29 Jun 2007

Scientists create sheets of protein-gold arrays

In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays.

28 Jun 2007

Polymeric nanoparticles show potential as new method for drug delivery

28 Jun 2007

Substance from lapacho tree could lead to new lung-cancer treatment

Researchers at UT Southwestern Medical Center have determined how a substance derived from the bark of the South American lapacho tree kills certain kinds of cancer cells, findings that also suggest a novel treatment for the most common type of lung cancer.

26 Jun 2007

Boston Scientific to acquire Remon Medical Technologies

Boston Scientific Corporation has announced it has signed a definitive agreement to acquire Remon Medical Technologies Inc., a privately held company based in Caesarea, Israel.

26 Jun 2007

Ranbaxy receives tentative FDA approval for Tamsulosin capsules

Ranbaxy Pharmaceuticals has announced that RLL has received tentative approval from the U.S. Food and Drug Administration to manufacture and market Tamsulosin Hydrochloride Capsules, 0.4 mg.

23 Jun 2007

Novel method of drug delivery to inhibit the growth of prostate cancer cells

Prostate cancer is the second leading cause of cancer-related death for men in the U.S. Present treatments for metastatic prostate cancer (cancer cells that spread to other parts of the body) include hormonal therapy, chemotherapy and radiotherapy, which frequently have serious side effects.

23 Jun 2007

BSD Medical files patent for 'smart bomb' delivery of chemotherapy in breast tumors

BSD Medical Corp. has filed a patent for a new non-invasive phased array breast treatment applicator developed to selectively heat breast cancer tumors.

19 Jun 2007

Focus on motor neurone disease

Motor neurone disease (MND), also known as amyotrophic lateral sclerosis, is a degenerative disease of unknown cause which causes patients to lose basic motor functions and has a devastating effect on them and their families.

17 Jun 2007

In vivo imaging of siRNA delivery and silencing in tumors

Using magnetic nanoparticles labeled with dye molecules, a team of investigators at the Massachusetts General Hospital has developed a delivery vehicle capable of transporting antitumor small interfering RNA (siRNA) molecules into cells.

14 Jun 2007

Hybrid gold-dendrimer nanoparticles target and image tumors

Dendrimer nanoparticles, made of spherical, highly branched polymers, have shown promise as drug delivery vehicles capable of targeting tumors with large doses of anticancer drugs.

14 Jun 2007

New drug-delivery system using nanomaterials

Researchers at UCLA have successfully manipulated nanomaterials to create a new drug-delivery system that promises to solve the challenge of the poor water solubility of today's most promising anticancer drugs and thereby increase their effectiveness.

8 Jun 2007

Designer lipid-like peptides to play a key role in improving drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants in the May 30th issue of the online, open-access journal PLoS ONE.

30 May 2007

Evaluation of leading combination regimens for treating malaria

Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA , a theme issue on malaria.

24 May 2007