Efficacy News and Research

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High-fiber diets may help control the adverse effects of antibiotic treatments on beneficial gut microbiota

The role of diet in controlling the structure and function of the gut via chemical environment modulation.

30 Aug 2023

An array of early psychological therapies in response to traumatic childbirth may buffer PTSD development

Researchers systematically reviewed and quantitatively assessed clinical trials on preventing Childbirth-Related Post-Traumatic Stress Disorder.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

Floatation therapy may be a novel treatment for anorexia nervosa

A trailblazing study conducted by researchers at the Laureate Institute for Brain Research (LIBR) in Tulsa, Okla., has made significant strides with a novel technique for treating anorexia nervosa (AN), an eating disorder characterized by low body weight, body image abnormalities, and anxiety.

29 Aug 2023

Light-driven bacteria could be used to target and kill cancer cells

Targeting malignant tumors with high precision is challenging for biomedical researchers. However, this scenario is likely to witness a paradigm shift in the near future, through the use of specially engineered bacteria, that can eliminate malignant cells efficiently.

29 Aug 2023

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

A University of Massachusetts Amherst biomedical engineer has used a nanogel-based carrier designed in his lab to deliver a drug exclusively to the liver of obese mice, effectively reversing their diet-induced disease.

29 Aug 2023

Anticoagulation after primary PCI does not prevent adverse outcomes in STEMI patients

Anticoagulation after primary percutaneous coronary intervention (PCI) does not prevent adverse outcomes in patients with ST-segment elevation myocardial infarction (STEMI), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Early initiation of dapagliflozin in acute decompensated heart failure does not improve diuretic efficiency

Early initiation of the sodium glucose co-transporter 2 (SGLT2) inhibitor dapagliflozin did not result in a statistically significant improvement in diuretic efficiency relative to structured usual care in hospitalized patients with acute decompensated heart failure (ADHF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Sodium glucose co-transporter-2 (SGLT2) inhibitors do not lead to lower 28-day all-cause mortality compared with usual care or placebo in patients hospitalized with COVID-19, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Inorganic nitrate reduces contrast-induced nephropathy (CIN), improves renal outcomes and reduces cardiac events compared to placebo in patients at risk of renal injury undergoing coronary angiography for acute coronary syndrome, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Analysis reveals limited evidence on use of cannabis products in children with cancer

A recent analysis of all relevant published studies reveals a lack of evidence to determine the dosing, safety, and efficacy of medical marijuana or cannabis-containing products for managing symptoms experienced by children with cancer.

29 Aug 2023

Can the fermentation of foods enhance their antioxidant properties?

In a recent editorial published in Fermentation, researchers highlighted the use of fermentation as a means to increase the antioxidant potential of foods.

29 Aug 2023

Omicron's dominance amidst immune escape sparks debate: should it be classified as a separate serotype?

Distinct serotypes for severe acute respiratory syndrome (SARS)-related coronaviruses (CoVs).

29 Aug 2023

Are we failing to bridge the gap in HPV vaccine coverage globally?

Study reveals stark global inequities in HPV vaccine coverage across 84 countries, finding that nations with the highest burden of cervical cancer often have the lowest vaccination rates. However, new WHO recommendations and an increase in vaccine supply may help narrow this gap and improve equitable access.

29 Aug 2023

OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) leads to a larger minimum stent area but does not reduce the two-year rate of target vessel failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Experts warn of unintended consequences of using GLP-1RAs to treat childhood obesity

A team of clinicians, exercise scientists, pharmaceutical scholars, ethicists and behavioral experts at the University of California, Irvine, outlined their concerns that the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) to treat childhood obesity and type 2 diabetes may have unintended and adverse consequences for children's health.

28 Aug 2023

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Pulsed field ablation (PFA) is as effective and safe as conventional thermal ablation for the treatment of paroxysmal atrial fibrillation (AF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Study shows efficacy and safety of OCT-guided strategy for percutaneous coronary intervention

Optical coherence tomography (OCT) is non-inferior to intravascular ultrasound (IVUS) for guiding percutaneous coronary intervention (PCI), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Acoramidis improves outcomes in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

Atrial fibrillation ablation is associated with lower rates of death, urgent heart transplantation or left ventricular assist device (LVAD) implantation compared with medical therapy in patients with end-stage heart failure, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Efficacy News and Research

High-fiber diets may help control the adverse effects of antibiotic treatments on beneficial gut microbiota

An array of early psychological therapies in response to traumatic childbirth may buffer PTSD development

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Floatation therapy may be a novel treatment for anorexia nervosa

Light-driven bacteria could be used to target and kill cancer cells

Drug-encapsulated nanogels show potential for treating obesity and other liver diseases

Anticoagulation after primary PCI does not prevent adverse outcomes in STEMI patients

Early initiation of dapagliflozin in acute decompensated heart failure does not improve diuretic efficiency

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Inorganic nitrate reduces contrast-induced nephropathy in high-risk patients

Analysis reveals limited evidence on use of cannabis products in children with cancer

Can the fermentation of foods enhance their antioxidant properties?

Omicron's dominance amidst immune escape sparks debate: should it be classified as a separate serotype?

Are we failing to bridge the gap in HPV vaccine coverage globally?

OCT-guided PCI does not reduce target vessel failure in complex patients, but improves safety

Experts warn of unintended consequences of using GLP-1RAs to treat childhood obesity

Pulsed field ablation safe, effective for the treatment of paroxysmal atrial fibrillation

Study shows efficacy and safety of OCT-guided strategy for percutaneous coronary intervention

Acoramidis shows potential to be effective, safe treatment for transthyretin amyloid cardiomyopathy

Ablation more effective than medical therapy in patients with end-stage heart failure, study shows

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Bringing real-time analytics to downstream bioprocess monitoring

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Evaluating new approaches for rare disease genomics

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