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A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

Research examines possibility of monkeypox transmission in domestic settings

In a recent article posted to the medRxiv* preprint server, researchers conducted environmental sampling for an imported monkeypox virus (MPXV) case in the United Kingdom (UK).

30 Jun 2022

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

A research team from the LKS Faculty of Medicine, The University of Hong Kong discovered more efficient CRISPR-Cas9 variants that could be useful for gene therapy applications.

30 Jun 2022

How to develop an "all-variant" COVID vaccine

In a recent study published in Nature Immunology, researchers summarized their observations of humoral immune responses elicited in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infected people. Additionally, they discussed all the types of SARS-CoV-2 infection- and vaccine-induced neutralizing antibodies (nAbs).

30 Jun 2022

Antibiotic-resistant strains of typhoid bacteria continue to spread out of South Asia

Antibiotic-resistant strains of Salmonella Typhi, the typhoid bacteria, have spread from South Asia to other countries nearly 200 times since 1990, new research suggests.

29 Jun 2022

NUS researchers discover a new way to interpret unsolved Mendelian diseases

The development of an embryo is a well-orchestrated string of processes, ensuring correct formation and positioning of vital organs of the growing organism.

29 Jun 2022

Study finds Omicron variant could break through vaccine protection more effectively than the Delta variant

Researchers assessed the efficacy of vaccinations against SARS-CoV-2 Delta and Omicron variants of concern.

29 Jun 2022

Drug-resistant typhoid needs to be treated as a global problem

The bacteria that causes typhoid fever is becoming increasingly resistant to common antibiotics used to treat the disease, with resistant strains spreading to hundreds of countries in the past three decades, new analysis shows.

29 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

New machine learning method may improve the identification of genes that cause diseases

A new machine learning method to model gene expression levels might improve the identification of genes that cause human diseases, according to a new study by Penn State College of Medicine researchers.

28 Jun 2022

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and the IrsiCaixa AIDS Research Institute, a center jointly promoted by the "la Caixa" Foundation and the Department of Health of the Generalitat de Catalunya.

28 Jun 2022

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.

28 Jun 2022

New technique offers higher-precision scRNA-seq data than current technologies

The advent of single-cell RNA sequencing (scRNA-seq) has revolutionized the fields of medicine and biology by providing the ability to study the inner workings of thousands of cells at one go.

28 Jun 2022

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Researchers performed genomic comparisons between alphacoronaviruses (αCoVs) and betacoronaviruses (βCoVs) originating from South Korean Bats.

28 Jun 2022

Evolution of SARS-CoV-2 genomes based on continuing positive selection

Researchers hypothesized that ongoing positive selection strongly influences SARS-CoV-2 genomes, which plays an important role in shaping the dynamics of the COVID-19 pandemic.

28 Jun 2022

A data commons to accelerate research in COVID and long-COVID

In a recent study posted to the medRxiv* pre-print server, researchers in the United States developed a pandemic response commons (PRC) called the Chicagoland coronavirus disease 2019 (COVID-19) commons (CCC). The CCC served Chicago, the state of Illinois, and surrounding regions in the United States (US).

28 Jun 2022

A cancer patient who had SARS-CoV-2 for over eight months

In a recent study posted to the medRxiv* pre-print server, researchers in Israel described the case of a severely immunocompromised cancer patient who developed a chronic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

More than 62,000 people in the United States will be diagnosed with pancreatic cancer by the end of this year, with the vast majority having a deadly and aggressive subtype known as pancreatic ductal adenocarcinoma (PDA).

27 Jun 2022

Genome News and Research

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Research examines possibility of monkeypox transmission in domestic settings

HKUMed researchers discover more efficient CRISPR-Cas9 variants for gene therapy applications

How to develop an "all-variant" COVID vaccine

Antibiotic-resistant strains of typhoid bacteria continue to spread out of South Asia

NUS researchers discover a new way to interpret unsolved Mendelian diseases

Study finds Omicron variant could break through vaccine protection more effectively than the Delta variant

Drug-resistant typhoid needs to be treated as a global problem

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

New machine learning method may improve the identification of genes that cause diseases

Antiretroviral drug used to treat HIV ameliorates cognitive deficits in mouse model of Down syndrome

Highly antibiotic-resistant strain of MRSA on pigs is capable of rapidly adapting to human hosts

New technique offers higher-precision scRNA-seq data than current technologies

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

Evolution of SARS-CoV-2 genomes based on continuing positive selection

A data commons to accelerate research in COVID and long-COVID

A cancer patient who had SARS-CoV-2 for over eight months

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

Researchers discover a molecular switch that promotes pancreatic cancer metastasis

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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