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Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis, a fatal degenerative disease.

1 Apr 2013

Post-2015 development agenda must address global health

"A proliferation of complex challenges to development, such as political conflict, economic austerity, and environmental degradation, all demand attention, but should not deflect from recognizing that good health is central to advancing global prosperity," GAVI Alliance CEO Seth Berkley, WHO Director-General Margaret Chan, Global Fund to Fight AIDS, TB and Malaria Executive Director Mark Dybul, World Bank Sector Manager for Health in Latin America Keith Hansen, UNICEF Executive Director Anthony Lake, UNFPA Executive Director Babatunde Osotimehin, and UNAIDS Executive Director Michel Sidibé, write in a Lancet opinion piece examining the post-2015 development agenda.

30 Mar 2013

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Five University of California, San Diego scientists and professors are among the first class of the Fellows of the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer.

29 Mar 2013

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

For years, scientists have been concerned about chemicals in the environment that mimic the estrogens found in the body. In study after study, researchers have found links between these "xenoestrogens" and such problems as decreased sperm viability, ovarian dysfunction, neurodevelopmental deficits and obesity.

29 Mar 2013

New study associates commonly used diabetes drugs with pancreatic cancer risk

ndividuals who had taken a type of drug commonly used to treat Type 2 diabetes showed abnormalities in the pancreas, including cell proliferation, that may be associated with an increased risk of neuroendocrine tumors, according to a new study by researchers from UCLA and the University of Florida.

28 Mar 2013

Scientists discover novel compounds that can lead to new strategies for treating diseases

Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety of responses including a strong anti-inflammatory effect.

26 Mar 2013

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer.

26 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

arGEN-X advances ARGX-112 into formal preclinical development

arGEN-X, a clinical stage biopharmaceutical company specialized in the discovery and development of highly differentiated human monoclonal antibody therapeutics, announces that it has progressed ARGX-112, its fourth therapeutic candidate, into formal preclinical development.

25 Mar 2013

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib for patients with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia resulting from MDS and have failed treatment with azanucleosides.

21 Mar 2013

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

A team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.

20 Mar 2013

ADP-ribose plays key role in repairing cellular DNA damage

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs.

13 Mar 2013

Swine study shows that moderate exercise can affect ovarian cells

A short walk around the barn might improve the future fertility of Yorkshire gilts. According to research presented by Samantha Kaminski, a graduate student at North Dakota State University, swine fetuses showed significant ovarian development after their mothers exercised.

13 Mar 2013

Targeting Mer receptors sensitize AML and ALL to chemotherapies

Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells - without affecting surrounding, healthy cells.

12 Mar 2013

SRSF1 protein can prevent cancerous proliferation by stabilizing p53

Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in Molecular Cell that the oncogenic protein SRSF1 can also trigger a stop in cell growth and prevent cancerous proliferation by stabilizing p53, the powerful tumor-suppressor protein.

8 Mar 2013

Horizon forms 3 new Centers of Excellence for gene editing in Asia

Horizon Discovery (Horizon), a leading provider of research tools to support the development of personalized medicines, today announced it has established three new Centers of Excellence (CoE's) for gene editing in Asia.

4 Mar 2013

Aquasana to introduce two filtration products at International Home + Housewares Show

Aquasana will make a splash at the International Home + Housewares Show in Chicago March 2-5 with the introduction of two groundbreaking filtration products. Both represent industry leadership for chloramine contamination reduction.

4 Mar 2013

Study instructs how to design new, more powerful vaccine formulas for cancer

Cancer vaccines that attempt to stimulate an immune system assault fail because the killer T cells aimed at tumors instead find the vaccination site a more inviting target, scientists at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

4 Mar 2013

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

New research published today in the Biochemical Journal describes the discovery of a new cancer target.

28 Feb 2013

Researchers discover that tympanic border cells can enable hearing

Researchers at the Stanford University School of Medicine have identified a group of progenitor cells in the inner ear that can become the sensory hair cells and adjacent supporting cells that enable hearing.

27 Feb 2013

Proliferation News and Research

Johns Hopkins scientists identify role of central nervous system cell in development of ALS

Post-2015 development agenda must address global health

AACR recognizes scientists whose contributions to cancer field have extraordinary impact

Exposure to multiple estrogen-mimicking chemicals distorts hormone action

New study associates commonly used diabetes drugs with pancreatic cancer risk

Scientists discover novel compounds that can lead to new strategies for treating diseases

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Two studies shed light on molecular biology of three blood disorders

arGEN-X advances ARGX-112 into formal preclinical development

Researchers complete phase II clinical trial of dasatinib for patients with higher-risk MDS

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

ADP-ribose plays key role in repairing cellular DNA damage

Swine study shows that moderate exercise can affect ovarian cells

Targeting Mer receptors sensitize AML and ALL to chemotherapies

SRSF1 protein can prevent cancerous proliferation by stabilizing p53

Horizon forms 3 new Centers of Excellence for gene editing in Asia

Aquasana to introduce two filtration products at International Home + Housewares Show

Study instructs how to design new, more powerful vaccine formulas for cancer

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

Researchers discover that tympanic border cells can enable hearing

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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