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Scientists discover c-Abl protein role in Parkinson's disease progression

Johns Hopkins scientists have discovered that the over-activation of a single protein may shut down the brain-protecting effects of a molecule and facilitate the most common form of Parkinson's disease.

4 Oct 2010

Researchers find new way to increase number of blood-forming stem cells when grown outside the body

One of the major challenges in stem cell transplants is how to obtain sufficient numbers of these remarkably rare cells to put into patients. To help overcome this issue, research from the Centenary Institute, Royal Prince Alfred Hospital and the University of Sydney has found a way to increase the number of blood-forming stem cells when growing them outside of the body.

4 Oct 2010

Advances in treatment and management of neurological disorders

The latest advances in treating neurologic disorders such as stroke, headache, Parkinson's disease, epilepsy and sleep disorders are detailed in a special issue of the journal Neurologic Clinics.

4 Oct 2010

Fred Hutchinson Center offers research-based tip sheets on breast cancer

Throughout October, National Breast Cancer Awareness Month, experts from Fred Hutchinson Cancer Research Center and its clinical care partner, the Seattle Cancer Care Alliance, are offering a series of weekly research-based tip sheets regarding a variety of topics related to breast cancer, including breast cancer prevention, screening and early detection, treatment, and survivorship.

4 Oct 2010

Researchers find gene variations in PDE11A enzyme can increase risk for prostate cancer

Researchers at the National Institutes of Health have found that variations in a gene for an enzyme involved in cell energy metabolism appear to increase the risk for prostate cancer.

4 Oct 2010

NIH announces it will share IP rights to some AIDS drugs in UNITAID Patent Pool

The NIH announced Thursday it will share intellectual property rights on some AIDS drugs in a patent pool designed to make treatments more widely available to the poor, Reuters reports.

4 Oct 2010

Study shows no difference between Bevacizumab and Ranibizumab efficacy in treating AMD

Researchers from Boston University School of Medicine (BUSM) and the VA Boston Healthcare System have conducted a study that failed to show a difference in efficacy between Bevacizumab (Avastin) and Ranibizumab (Lucentis) for the treatment of age-related macular degeneration (AMD).

4 Oct 2010

New American Therapeutics acquires U.S. rights to market Denavir drug

New American Therapeutics, Inc., announced today that it acquired all U.S. rights to manufacture, market and sell the antiviral topical drug Denavir owned by Novartis.

4 Oct 2010

Report says drugmakers failing to give Medicaid adequate price data

Drug manufacturers often flout a federal law that requires them to provide the government with pricing data needed to calculate discounts on medications prescribed for poor people under Medicaid, federal investigators say in a new report.

4 Oct 2010

Research Roundups: Racial Disparities at end of life; stopping medicine mistakes; Grand Junction, Colorado's Cost Lessons

Racial Disparities In The Outcomes Of Communication On Medical Care Received Near Death Black patients receive more life prolonging measures and less comfort-directed care at the end of life (EOL) than white patients, such as increased rates of resuscitation, intensive care unit hospitalization, and feeding tube use at the EOL, write the authors of this study that examined whether differences in patient-physician communication contribute to these differences.

4 Oct 2010

NIH awards Scripps Research grants to study the mechanisms of protein complex

For Immediate Release -Scripps Research Institute scientists have been awarded approximately $65 million in four five-year grants as part of the National Institutes of Health's (NIH) latest round of structural biology funding. The projects will focus on determining the shapes and functions of proteins and protein complexes that are important in biology and medicine.

4 Oct 2010

Study on immune system activation may help develop new drugs for infections

A new research report in the October 2010 print issue of the Journal of Leukocyte Biology sheds important light on how our immune systems detect invading organisms to be destroyed and removed from our bodies. The information from this research should ultimately help lead to the development of new drugs and treatments that allow health care providers to prevent runaway immune reactions that can have devastating consequences for people.

4 Oct 2010

Researchers discover new mechanism of DNA repair process

Tucked within its double-helix structure, DNA contains the chemical blueprint that guides all the processes that take place within the cell and are essential for life. Therefore, repairing damage and maintaining the integrity of its DNA is one of the cell's highest priorities.

4 Oct 2010

PDGFR gene rearrangements lead to aggressive form of glioblastoma: Study

4 Oct 2010

HHS consumer website adds new features; health law provisions affecting open season

HealthCare.Gov, the consumer health care insurance website run by the federal government, unveiled a slew of new features this morning. Consumers can find pricing information for 4,400 individual and family health plans offered by more than 225 insurance carriers, Plan information will be updated monthly, said Todd Park, HHS chief technology officer.

4 Oct 2010

Efforts against drug-resistant malaria along Thai-Cambodian border show progress, but more 'aggressive' approach needed, health officials say

Efforts to prevent the spread of drug-resistant malaria along the border between Cambodia and Thailand are showing signs of progress, but additional work is needed to contain the new strain, health officials said on Friday, Deutsche Presse-Agentur/M&C reports.

4 Oct 2010

Osteoporosis common but underestimated in old men: Study

According to the latest research osteoporosis a diseases common in women that makes bones brittle and easily breakable with age also affects men. The study suggests that this debilitating condition is often overlooked in elderly Australian men.

3 Oct 2010

Bloomberg analysis finds 'doughnut hole' deal to cost drugmakers less than 1% of profits

News outlets report how closing the Medicare 'Doughnut Hole' affects drugmakers and seniors.

1 Oct 2010

Merck to pay millions over Mass. allegations of inflated wholesale rate

Bloomberg Businessweek: A Massachusetts court ordered the drug maker Merck to pay $4.6 million in damages for inflating wholesale prices for generic asthma drugs. "Massachusetts claimed the companies reported inflated wholesale acquisition-cost prices for the generics, and that MassHealth, the state component of the Medicaid program, would rely on those prices for reimbursements" (McQuillen, 9/30).

1 Oct 2010

Activating rearrangements in receptor genes are more common than previously thought

A multi-institutional team led by investigators from Memorial Sloan-Kettering Cancer Center has published a study that provides new insight into genetic changes that make some forms of glioblastoma, the most common type of primary brain cancer, more aggressive than others and explains why they may not respond to certain therapies. The research was led by senior author Eric C. Holland, MD, PhD,--an MSKCC surgeon, researcher and the Director of the Brain Tumor Center--and was published in the October 1 issue of the journal Genes & Development.

1 Oct 2010

Drugs News and Research

Scientists discover c-Abl protein role in Parkinson's disease progression

Researchers find new way to increase number of blood-forming stem cells when grown outside the body

Advances in treatment and management of neurological disorders

Fred Hutchinson Center offers research-based tip sheets on breast cancer

Researchers find gene variations in PDE11A enzyme can increase risk for prostate cancer

NIH announces it will share IP rights to some AIDS drugs in UNITAID Patent Pool

Study shows no difference between Bevacizumab and Ranibizumab efficacy in treating AMD

New American Therapeutics acquires U.S. rights to market Denavir drug

Report says drugmakers failing to give Medicaid adequate price data

Research Roundups: Racial Disparities at end of life; stopping medicine mistakes; Grand Junction, Colorado's Cost Lessons

NIH awards Scripps Research grants to study the mechanisms of protein complex

Study on immune system activation may help develop new drugs for infections

Researchers discover new mechanism of DNA repair process

PDGFR gene rearrangements lead to aggressive form of glioblastoma: Study

HHS consumer website adds new features; health law provisions affecting open season

Efforts against drug-resistant malaria along Thai-Cambodian border show progress, but more 'aggressive' approach needed, health officials say

Osteoporosis common but underestimated in old men: Study

Bloomberg analysis finds 'doughnut hole' deal to cost drugmakers less than 1% of profits

Merck to pay millions over Mass. allegations of inflated wholesale rate

Activating rearrangements in receptor genes are more common than previously thought

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