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Physiology-guided complete revascularization reduces ischemic events in older MI patients

Physiology-guided complete revascularization reduces ischemic events compared with culprit-only revascularization in myocardial (MI) infarction patients aged 75 years or older with multivessel disease, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Dual-antiplatelet therapy should remain the standard strategy for PCI even in the drug-eluting stent era

Prasugrel monotherapy after percutaneous coronary intervention (PCI) with drug-eluting stents is not superior to dual-antiplatelet therapy (DAPT) for major bleeding but is non-inferior for cardiovascular events in patients with acute coronary syndrome (ACS) or high bleeding risk (HBR), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

CRT-D upgrade reduces morbidity and mortality in HFrEF patients with RV pacing

Upgrade to cardiac resynchronization therapy with a defibrillator (CRT-D) reduces morbidity and mortality and improves left ventricular (LV) reverse remodeling compared to an implantable cardioverter-defibrillator (ICD) in select patients with heart failure and reduced ejection fraction (HFrEF) and intermittent or permanent right ventricular (RV) pacing, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

Study shows benefit of traditional Chinese medicine for heart failure

The traditional Chinese medicine qiliqiangxin reduces hospitalization for heart failure and cardiovascular death in patients with heart failure and a reduced ejection fraction (HFrEF), according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

28 Aug 2023

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Researchers discuss the potential of probiotic- and prebiotic-based interventions for managing cardiovascular diseases.

28 Aug 2023

Subcutaneous anchors more effective than adhesives in securing catheters

The largest study of patients with peripherally inserted central catheters (PICC) utilizing a subcutaneous anchoring securement system (SASS) ever conducted shows that using subcutaneous anchors to secure catheters is more effective than using adhesive securement devices (ASD).

25 Aug 2023

Processing speed influences memory rehabilitation outcomes in TBI patients

Scientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment benefits of the Kessler Foundation modified Story Memory Technique (KF-mSMT) in individuals with moderate to severe traumatic brain injury (TBI).

25 Aug 2023

NIH and VentureWell select winners and honorable mentions of the DEBUT Challenge

The National Institutes of Health and the higher education non-profit VentureWell have selected 10 winners and five honorable mentions of the Design by Biomedical Undergraduate Teams (DEBUT) Challenge, who are set to receive prizes totaling $145,000.

25 Aug 2023

Study shows not all adrenal carcinoma patients need mitotane after surgery

After the complete tumor resection, not all patients with an adrenocortical carcinoma require the previous standard therapy Mitotane. Professors Martin Fassnacht and Massimo Terzolo show this in a clinical trial.

25 Aug 2023

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines is published online today in European Heart Journal following the results of major new trials that should change the management of patients with heart failure.

25 Aug 2023

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Blood thinners (anticoagulants) cause bleeding without preventing stroke in patients with atrial high rate episodes (AHRE), but without electrocardiogram (ECG)-diagnosed atrial fibrillation, according to late breaking research presented in a Hot Line session today at ESC Congress 2023 and simultaneously published in the New England Journal of Medicine.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Voluntary collective isolation ineffective in preventing COVID-19 spread among Indigenous populations

Indigenous Peoples have suffered disproportionally from the ongoing COVID-19 pandemic. Systemic factors including lack of sovereignty, limited infrastructure and discrimination in local health care systems make Indigenous populations vulnerable to infectious diseases.

24 Aug 2023

New research sheds light on role of KRAS mutations in pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have uncovered a functional role for KRAS mutations in pancreatic cancer and rapidly translated these findings into a novel therapeutic approach combining a KRAS G12D inhibitor with immune checkpoint inhibitors for early- and late-stage KRAS G12D-mutant pancreatic cancer.

24 Aug 2023

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

How does ophthalmology advice generated by a large language model chatbot compare with advice written by ophthalmologists?

A study claims that the quality of AI-generated responses to patient eye care questions is comparable to that of certified ophthalmologists.

24 Aug 2023

Efficacy News and Research

Physiology-guided complete revascularization reduces ischemic events in older MI patients

Dual-antiplatelet therapy should remain the standard strategy for PCI even in the drug-eluting stent era

CRT-D upgrade reduces morbidity and mortality in HFrEF patients with RV pacing

Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

Study shows benefit of traditional Chinese medicine for heart failure

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Subcutaneous anchors more effective than adhesives in securing catheters

Processing speed influences memory rehabilitation outcomes in TBI patients

NIH and VentureWell select winners and honorable mentions of the DEBUT Challenge

Study shows not all adrenal carcinoma patients need mitotane after surgery

Focused update of ESC Heart Failure Guidelines integrates latest evidence-based treatments

NOAH-AFNET 6 trial: Oral anticoagulation not recommended for patients with atrial high rate episodes

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Voluntary collective isolation ineffective in preventing COVID-19 spread among Indigenous populations

New research sheds light on role of KRAS mutations in pancreatic cancer

Stem cell patch for treating macular degeneration to enter phase 2b clinical trial

UTMB research potentially points to an effective treatment for Lassa fever

Ketogenic diets, gut microbiota, and health effects

Small molecule inhibitor of the NLRP3 inflammasome for treating autoinflammatory diseases

How does ophthalmology advice generated by a large language model chatbot compare with advice written by ophthalmologists?

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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