immunity News and Research

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Researchers create model to explore SARS-CoV-2 Omicron and Delta supremacy

In a new study, researchers have created a model to help identify the dynamics of Delta and Omicron infection in the US, as well as explore the effects of various factors on the overall COVID-19 pandemic.

28 Feb 2022

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Researchers conducted a national epidemiological survey to determine the seropositivity against SARS-CoV-2 before the emergence of the novel Omicron variant of concern.

28 Feb 2022

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

A recent study observed that peptide-based vaccination against SARS-CoV-2 failed to protect mice against COVID-19, albeit eliciting T cell responses.

28 Feb 2022

Parents should know their children's cholesterol levels, expert says

Today, the main focus is on lowering high cholesterol levels in adults in order to prevent atherosclerosis. Professor Kirsten Holvenat the Department of Nutrition at the University of Osloissues a clear warning: we start the process of prevention too late, when the narrowing of arteries is already too far advanced. She advocates that parents should know the level of their children's cholesterol.

28 Feb 2022

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Researchers emphasized the need to take on a holistic and unbiased approach to develop a universal vaccine for coronaviruses, including SARS-CoV-2, which is a biomedical priority during the ongoing COVID-19 pandemic.

28 Feb 2022

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A new study discusses the emergence of new variants of SARS-CoV-2 that can escape antibody-mediated neutralization, as opposed to other Sarbecoviruses.

27 Feb 2022

A promising new vaccine for SARS-CoV-2 and influenza

Researchers create a vaccine candidate that could protect against both SARS-CoV-2 and IAVs.

27 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers - and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Mosquito net use in early childhood increases chances of survival into adulthood

Children who sleep more often under insecticide-treated bed nets have more than 40 per cent higher likelihood of surviving into adulthood than their counterparts who use bed nets less often, a study suggests.

25 Feb 2022

Outcomes of SARS-Cov-2 infection in patients undergoing active anti-cancer treatment

Researchers demonstrated that irrespective of the type of ACT, SARS-CoV-2 infection rates in patients receiving ACT remained comparable to the general population.

25 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

mRNA vaccines found to be highly effective against COVID-19 infections before the emergence of SARS-CoV-2 Delta variant

Researchers evaluated the efficacy of SARS-CoV-2 vaccines made by Pfizer, Jansen, and Moderna against symptomatic and asymptomatic COVID-19 cases.

25 Feb 2022

Severe COVID-19 outcomes in breakthrough infections in patients being treated with B cell depleting therapy

Scientists evaluated the incidence and severity of breakthrough SARS-CoV-2 infections among individuals with immune-mediated inflammatory diseases undergoing B cell depleting therapy.

25 Feb 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Researchers characterized humoral and SARS-CoV-2 S-specific T cell responses in IBD patients who received two-dose mRNA-based COVID-19 vaccination series.

25 Feb 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

Researchers assess the serological response to a real-world COVID-19 vaccination strategy in older individuals who resided in long-term care facilities.

24 Feb 2022

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

Insilico Medicine, an end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that it has dosed multiple healthy volunteers in Phase I clinical trial evaluating ISM001-055, the first anti-fibrotic small molecule inhibitor generated by Insilico's AI-powered drug discovery platform for idiopathic pulmonary fibrosis (IPF).

24 Feb 2022

immunity News and Research

Researchers create model to explore SARS-CoV-2 Omicron and Delta supremacy

Immunity before and after the SARS-CoV-2 Omicron variant in South Africa

Peptide-based vaccine fails to protect mice against SARS-CoV-2 despite T cell response

Parents should know their children's cholesterol levels, expert says

The need for a holistic and unbiased approach to develop a more universal vaccine for coronaviruses

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

Emergence of SARS-CoV-2 Omicron likely due to immune selective pressure

A promising new vaccine for SARS-CoV-2 and influenza

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Mosquito net use in early childhood increases chances of survival into adulthood

Outcomes of SARS-Cov-2 infection in patients undergoing active anti-cancer treatment

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

mRNA vaccines found to be highly effective against COVID-19 infections before the emergence of SARS-CoV-2 Delta variant

Severe COVID-19 outcomes in breakthrough infections in patients being treated with B cell depleting therapy

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

T cell responses in inflammatory bowel disease patients on immune-modifying agents after mRNA COVID-19 vaccination

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Serological responses to heterologous COVID-19 mRNA vaccination in older individuals

Phase I clinical trial evaluates AI-discovered first anti-fibrotic small molecule inhibitor

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