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Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

Convergence Pharmaceuticals Limited, the company focused on the development of novel and high value analgesic medicines, today announces that the multiple ascending dose Phase I study of the novel, first in class calcium channel blocker CNV2197944, for the treatment of chronic pain has been initiated.

21 Nov 2011

Avidocin protein could prevent or treat E. coli O157:H7-induced diarrhea

A novel antibacterial protein targeted against E. coli O157:H7 may offer a way to prevent or treat serious food-borne bacterial infections, as demonstrated in a study published in the December issue of Antimicrobial Agents and Chemotherapy.

21 Nov 2011

Promising results from dexpramipexole phase 2 trial on ALS

Treatment with dexpramipexole - a novel drug believed to prevent dysfunction of mitochondria, the subcellular structures that provide most of a cell's energy - appears to slow symptom progression in the neurodegenerative disease amyotrophic lateral sclerosis (ALS). Promising results of a phase 2 trial of dexpramipexole are receiving advance online publication in Nature Medicine.

20 Nov 2011

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

"I know I need this medicine to help lower my chance of cancer recurrence, but it makes my joints ache and stiff. It makes me feel old and I am not sure I can take this medication much longer."

19 Nov 2011

Colo. Gov. dismisses GOP call for Medicaid waivers; Fla. sanctions Medicaid docs

Colorado Gov. John Hickenlooper on Thursday rejected a Republican suggestion that he seek a federal waiver to rules governing Medicaid to balance the state budget. The Democratic governor's reaction comes amid a standoff with Republicans over suspending a property-tax break for seniors that costs the state $100 million a year.

19 Nov 2011

Roundup: Fla. Medicare HMO closed; Tufts and BCBS resume talks

Quality Health Plans, a Medicare HMO with 10,000 Florida members, has been ordered into liquidation after failing to come up with the cash reserves the state says were needed. Its members will be moved to another -- still unnamed -- plan by Dec. 1.

19 Nov 2011

New class of malaria drugs could be used as both prevention, treatment, study shows

"A group of researchers led by Novartis AG have discovered novel malaria compounds that may prove to be more efficient than currently available treatments and could be used as a prophylactic," the Wall Street Journal reports.

19 Nov 2011

Avastin drug not safe and effective for breast cancer patients: FDA Commissioner

FDA Commissioner Margaret A. Hamburg, M.D., said today she is revoking the agency's approval of the breast cancer indication for Avastin (bevacizumab) after concluding that the drug has not been shown to be safe and effective for that use.

19 Nov 2011

FDA approves EUSA's orphan drug ERWINAZE for acute lymphoblastic leukemia

EUSA Pharma, a transatlantic specialty pharmaceutical company focused on oncology, oncology supportive care and critical care, today announced that the US Food and Drug Administration (FDA) has approved its orphan drug ERWINAZE (asparaginase Erwinia chrysanthemi) for the treatment of acute lymphoblastic leukemia (ALL) in patients with hypersensitivity to E. coli-derived asparaginase.

19 Nov 2011

CHCWM, Priority Health partner to explore oncology patient-centered medical home

In keeping with society's urgent need for more efficient and effective health care, Priority Health and Cancer and Hematology Centers of West Michigan (CHCWM) have joined forces to explore an innovative oncology patient-centered medical home.

19 Nov 2011

FDA approves EYLEA for treatment of wet Age-related Macular Degeneration

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has approved EYLEA (aflibercept) Injection, known in the scientific literature as VEGF Trap-Eye, for the treatment of patients with neovascular (wet) Age-related Macular Degeneration (AMD) at a recommended dose of 2 milligrams every four weeks for the first 12 weeks, followed by 2 mg every eight weeks.

19 Nov 2011

Scientists identify novel gene mutation that causes glioblastoma

Scientists at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center, in collaboration with colleagues in Boston and South Korea, say they have identified a novel gene mutation that causes at least one form of glioblastoma (GBM), the most common type of malignant brain tumor.

18 Nov 2011

Cancer Research UK embarks on new initiative to unravel genetic secrets behind cancers

Unravelling the genetic secrets behind a range of cancers - from understanding how certain genes control cancer to determining how the disease evades treatment - is the aim of a new initiative from Cancer Research UK.

18 Nov 2011

EUSA Pharma receives FDA approval for Erwinaze to treat ALL

The U.S. Food and Drug Administration today approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy (hypersensitivity) to E. coli derived asparaginase and pegaspargase chemotherapy drugs used to treat ALL.

18 Nov 2011

HVTN debunks top 10 myths about HIV vaccine research

Dec. 1 is World AIDS Day, and in commemoration of the occasion, the HIV Vaccine Trials Network, headquartered at Fred Hutchinson Cancer Research Center, debunks the top 10 myths about HIV vaccine research.

18 Nov 2011

Resistance of starved bacteria can be blocked

Many infections, even those caused by antibiotic-sensitive bacteria, resist treatment. This paradox has vexed physicians for decades, and makes some infections impossible to cure.

18 Nov 2011

Important clues to prevention and management of delirium are being ignored

Important clues to the prevention and management of delirium, a condition affecting an estimated 7 million hospitalized Americans, are being ignored, according to a study from the Regenstrief Institute and the Indiana University School of Medicine.

18 Nov 2011

Researchers discover new class of antimalarial compounds

Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream.

18 Nov 2011

Simple roundworm may serve as ideal skin wound healing lab model

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body's response to healing skin wounds, a serious problem in diabetics and the elderly.

18 Nov 2011

Examining funding in light of new evidence on HIV prevention, treatment strategies

In this Huffington Post opinion piece, Nancy Birdsall, president of the Center for Global Development, reports on a World Bank- and USAID-sponsored debate she moderated last week as part of a series on HIV/AIDS issues, the topic of which was "Countries should spend a majority of what is likely to be a flat or even declining HIV prevention budget on 'treatment as prevention.'"

18 Nov 2011

Drugs News and Research

Convergence commences CNV2197944 multiple ascending dose Phase I study for chronic pain

Avidocin protein could prevent or treat E. coli O157:H7-induced diarrhea

Promising results from dexpramipexole phase 2 trial on ALS

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

Colo. Gov. dismisses GOP call for Medicaid waivers; Fla. sanctions Medicaid docs

Roundup: Fla. Medicare HMO closed; Tufts and BCBS resume talks

New class of malaria drugs could be used as both prevention, treatment, study shows

Avastin drug not safe and effective for breast cancer patients: FDA Commissioner

FDA approves EUSA's orphan drug ERWINAZE for acute lymphoblastic leukemia

CHCWM, Priority Health partner to explore oncology patient-centered medical home

FDA approves EYLEA for treatment of wet Age-related Macular Degeneration

Scientists identify novel gene mutation that causes glioblastoma

Cancer Research UK embarks on new initiative to unravel genetic secrets behind cancers

EUSA Pharma receives FDA approval for Erwinaze to treat ALL

HVTN debunks top 10 myths about HIV vaccine research

Resistance of starved bacteria can be blocked

Important clues to prevention and management of delirium are being ignored

Researchers discover new class of antimalarial compounds

Simple roundworm may serve as ideal skin wound healing lab model

Examining funding in light of new evidence on HIV prevention, treatment strategies

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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